DK536083A - Dna-sekvenser indeholdende modificeret proinsulin-precursorer og fremstilling og anvendelse heraf - Google Patents

Dna-sekvenser indeholdende modificeret proinsulin-precursorer og fremstilling og anvendelse heraf Download PDF

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Publication number
DK536083A
DK536083A DK536083A DK536083A DK536083A DK 536083 A DK536083 A DK 536083A DK 536083 A DK536083 A DK 536083A DK 536083 A DK536083 A DK 536083A DK 536083 A DK536083 A DK 536083A
Authority
DK
Denmark
Prior art keywords
preparation
dna sequences
containing modified
sequences containing
modified proinsulin
Prior art date
Application number
DK536083A
Other languages
English (en)
Other versions
DK536083D0 (da
Inventor
Brian S Seed
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of DK536083D0 publication Critical patent/DK536083D0/da
Publication of DK536083A publication Critical patent/DK536083A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK536083A 1982-03-31 1983-11-23 Dna-sekvenser indeholdende modificeret proinsulin-precursorer og fremstilling og anvendelse heraf DK536083A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36365782A 1982-03-31 1982-03-31
PCT/US1983/000482 WO1983003413A1 (en) 1982-03-31 1983-03-31 Creation of dna sequences encoding modified proinsulin precursors

Publications (2)

Publication Number Publication Date
DK536083D0 DK536083D0 (da) 1983-11-23
DK536083A true DK536083A (da) 1983-11-23

Family

ID=23431133

Family Applications (1)

Application Number Title Priority Date Filing Date
DK536083A DK536083A (da) 1982-03-31 1983-11-23 Dna-sekvenser indeholdende modificeret proinsulin-precursorer og fremstilling og anvendelse heraf

Country Status (6)

Country Link
EP (1) EP0090433A1 (da)
JP (1) JPS58183659A (da)
DK (1) DK536083A (da)
FI (1) FI834213A0 (da)
NO (1) NO834392L (da)
WO (1) WO1983003413A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663285A (en) * 1981-01-06 1987-05-05 The Public Health Laboratory Service Board Chimeric plasmids
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US4569792A (en) * 1984-06-14 1986-02-11 Eli Lilly And Company Anti-diabetic compounds
WO1986001540A1 (en) * 1984-08-31 1986-03-13 Genetics Institute, Inc. Modified insulin precursors products and processes
US6040166A (en) 1985-03-28 2000-03-21 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences, including a probe
US6197563B1 (en) 1985-03-28 2001-03-06 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences
FR2592060A1 (fr) * 1985-12-20 1987-06-26 Nautilus Molecule de synthese de nature caseinique, riche en methionine et procede d'obtention a l'echelle de la production industrielle

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
SK278170B6 (en) * 1977-11-08 1996-03-06 Keiichi Itakura Recombinant plasmid, method of its preparation and bacteria transformed by them
US4293652A (en) * 1979-05-25 1981-10-06 Cetus Corporation Method for synthesizing DNA sequentially
GR70279B (da) * 1979-09-12 1982-09-03 Univ California
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
US4351901A (en) * 1980-03-24 1982-09-28 Cetus Corporation Method for single nucleotide alteration
CA1154435A (en) * 1980-03-27 1983-09-27 Bruce H. Frank Process for producing an insulin precursor
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
IL62553A (en) * 1980-06-06 1984-12-31 Biogen Nv Vectors comprising dna sequences comprising at least one promoter and operator derived from bacteriophage ypsilon and methods for producing such recombinant dna molecules and cloning vectors
DD154547A1 (de) * 1980-08-04 1982-03-31 Liebscher Dirck Hartmut Verfahren zur klonierung des vollstaendigen gens von karpfen-prae-proinsulin
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
CA1204682A (en) * 1981-06-19 1986-05-20 Saran A. Narang Adaptors, and synthesis and cloning of proinsulin genes
ZA824218B (en) * 1981-06-29 1983-04-27 Cetus Corp Plasmid for producing human insulin

Also Published As

Publication number Publication date
WO1983003413A1 (en) 1983-10-13
JPS58183659A (ja) 1983-10-26
NO834392L (no) 1983-11-29
FI834213A (fi) 1983-11-17
FI834213A0 (fi) 1983-11-17
DK536083D0 (da) 1983-11-23
EP0090433A1 (en) 1983-10-05

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment