DK524788A - APPLICATION OF MORPHINE ANTAGONISTS FOR THE PREPARATION OF IMMUNO MODULATING AND ANTIVIRAL EFFECTS, IN PARTICULAR FOR TREATMENT OF ACQUIRED IMMUNDEFECT CONDITIONS - Google Patents

APPLICATION OF MORPHINE ANTAGONISTS FOR THE PREPARATION OF IMMUNO MODULATING AND ANTIVIRAL EFFECTS, IN PARTICULAR FOR TREATMENT OF ACQUIRED IMMUNDEFECT CONDITIONS

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Publication number
DK524788A
DK524788A DK524788A DK524788A DK524788A DK 524788 A DK524788 A DK 524788A DK 524788 A DK524788 A DK 524788A DK 524788 A DK524788 A DK 524788A DK 524788 A DK524788 A DK 524788A
Authority
DK
Denmark
Prior art keywords
preparation
treatment
acquired
immundefect
conditions
Prior art date
Application number
DK524788A
Other languages
Danish (da)
Other versions
DK524788D0 (en
Inventor
Marc Yves Franck Clemen Shelly
Original Assignee
Marc Yves Franck Clemen Shelly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marc Yves Franck Clemen Shelly filed Critical Marc Yves Franck Clemen Shelly
Publication of DK524788D0 publication Critical patent/DK524788D0/en
Publication of DK524788A publication Critical patent/DK524788A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/34Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/35Corticotropin [ACTH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Abstract

Utilization of morphine antagonists, such as Naltrexone, beta-endorphine 1-27, or their derivatives or analogs, in the preparation of an immunomodulator and/or antiviral drug for the treatment of acquired immunodeficiency states, particularly the infection by HIV.
DK524788A 1987-01-21 1988-09-21 APPLICATION OF MORPHINE ANTAGONISTS FOR THE PREPARATION OF IMMUNO MODULATING AND ANTIVIRAL EFFECTS, IN PARTICULAR FOR TREATMENT OF ACQUIRED IMMUNDEFECT CONDITIONS DK524788A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8700670A FR2609632B1 (en) 1987-01-21 1987-01-21 NOVEL THERAPEUTIC APPLICATION OF 17- (CYCLOPROPYLMETHYL) -4,5-EPOXY-3,14-DIHYDROXYMORPHINON-6-ONE AND PHARMACEUTICAL COMPOSITIONS FOR THIS USE
PCT/FR1988/000032 WO1988005297A1 (en) 1987-01-21 1988-01-21 Utilization of morphine antagonists in the preparation of drugs having an immunomodulator and antiviral effect, particularly for treating acquired immunodeficiency states

Publications (2)

Publication Number Publication Date
DK524788D0 DK524788D0 (en) 1988-09-21
DK524788A true DK524788A (en) 1988-11-18

Family

ID=9347124

Family Applications (1)

Application Number Title Priority Date Filing Date
DK524788A DK524788A (en) 1987-01-21 1988-09-21 APPLICATION OF MORPHINE ANTAGONISTS FOR THE PREPARATION OF IMMUNO MODULATING AND ANTIVIRAL EFFECTS, IN PARTICULAR FOR TREATMENT OF ACQUIRED IMMUNDEFECT CONDITIONS

Country Status (9)

Country Link
EP (1) EP0278821B1 (en)
JP (1) JPH02502278A (en)
AT (1) ATE112488T1 (en)
AU (1) AU610561B2 (en)
DE (1) DE3851711D1 (en)
DK (1) DK524788A (en)
FR (1) FR2609632B1 (en)
OA (1) OA09124A (en)
WO (1) WO1988005297A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5095035A (en) * 1981-07-31 1992-03-10 Eby Iii George A Flavor stable zinc acetate compositions for oral absorption
US4877791A (en) * 1988-11-01 1989-10-31 Baker Cummins Pharmaceuticals, Inc. Method of treatment for interestitial cystitis
US4857533A (en) * 1988-12-15 1989-08-15 Baker Cummins Pharmaceuticals, Inc. Method of treatment for autoimmune diseases
US4863928A (en) * 1989-01-04 1989-09-05 Baker Cummins Pharmaceuticals, Inc. Method of treatment for arthritic and inflammatory diseases
RU2058553C1 (en) * 1994-03-18 1996-04-20 Иван Николаевич Головистиков Method of estimation of human immune status suppressive link
RU2056852C1 (en) * 1994-03-18 1996-03-27 Иван Николаевич Головистиков Agent for treatment of autoimmune diseases with suppressor immunodeficiency and a method of autoimmune diseases treatment
US6274591B1 (en) 1997-11-03 2001-08-14 Joseph F. Foss Use of methylnaltrexone and related compounds
US20030229111A1 (en) * 2002-03-14 2003-12-11 Benjamin Oshlack Naltrexone hydrochloride compositions
DK1615646T4 (en) 2003-04-08 2022-10-10 Progenics Pharm Inc PHARMACEUTICAL FORMULATIONS CONTAINING METHYLNALTREXONE
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
ES2714198T3 (en) 2005-03-07 2019-05-27 Univ Chicago Use of opioid antagonists to attenuate the proliferation and migration of endothelial cells
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
AR057325A1 (en) 2005-05-25 2007-11-28 Progenics Pharm Inc SYNTHESIS OF (S) -N-METHYLNTREXONE, PHARMACEUTICAL COMPOSITIONS AND USES
AR057035A1 (en) 2005-05-25 2007-11-14 Progenics Pharm Inc SYNTHESIS OF (R) -N-METHYLNTREXONE, PHARMACEUTICAL COMPOSITIONS AND USES
TWI466671B (en) 2007-03-29 2015-01-01 Progenics Pharm Inc Peripheral opioid receptor antagonists and uses thereof
CA2865389A1 (en) 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Crystal forms and uses thereof
SI2565195T1 (en) 2007-03-29 2015-09-30 Wyeth Llc Peripheral opioid receptor and antagonists and uses thereof
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
AU2009225434B2 (en) 2008-03-21 2014-05-22 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
WO2017141104A2 (en) * 2016-02-18 2017-08-24 Immune Therapeutics, Inc. Method for inducing a sustained immune response
US11285192B2 (en) 2019-03-13 2022-03-29 Adamis Pharmaceuticals Corporation Formulation including a combination of beta-endorphin and adrenocorticotropic hormone
MX2021010989A (en) * 2019-03-13 2021-10-01 Adamis Pharmaceuticals Corp Formulation including a combination of î²-endorphin and adrenocorticotropic hormone.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives

Also Published As

Publication number Publication date
WO1988005297A1 (en) 1988-07-28
FR2609632A1 (en) 1988-07-22
EP0278821B1 (en) 1994-10-05
AU1189688A (en) 1988-08-10
AU610561B2 (en) 1991-05-23
OA09124A (en) 1991-10-31
JPH02502278A (en) 1990-07-26
FR2609632B1 (en) 1991-03-29
EP0278821A1 (en) 1988-08-17
DE3851711D1 (en) 1994-11-10
DK524788D0 (en) 1988-09-21
ATE112488T1 (en) 1994-10-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment