ES2130114T3 - 5,11-DIHIDRO-6H-DIPIRIDO (3,2-B: 2 ', 3'-E) (1,4) DIAZEPINES AND ITS USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION. - Google Patents

5,11-DIHIDRO-6H-DIPIRIDO (3,2-B: 2 ', 3'-E) (1,4) DIAZEPINES AND ITS USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION.

Info

Publication number
ES2130114T3
ES2130114T3 ES90121954T ES90121954T ES2130114T3 ES 2130114 T3 ES2130114 T3 ES 2130114T3 ES 90121954 T ES90121954 T ES 90121954T ES 90121954 T ES90121954 T ES 90121954T ES 2130114 T3 ES2130114 T3 ES 2130114T3
Authority
ES
Spain
Prior art keywords
dipirido
prevention
treatment
hiv infection
dihidro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90121954T
Other languages
Spanish (es)
Inventor
Karl D Dr Hargrave
Gunther Dr Schmidt
Wolfhard Dr Engel
Gunther Dr Trummlitz
Wolfgang Dr Eberlein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
BOEHRINGER INGELHEIM PHARMA
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27412005&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2130114(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BOEHRINGER INGELHEIM PHARMA, Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical BOEHRINGER INGELHEIM PHARMA
Application granted granted Critical
Publication of ES2130114T3 publication Critical patent/ES2130114T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Abstract

SE EXPONEN LAS NUEVAS 5,11-DIHIDRO-6H-DIPIRIDO[3, 2-B; 2'', 3''-E] [1,4]DIACEPINAS. SE UTILIZAN EN LA PREVENCION O TRATAMIENTO DE LA INFECCION HIV.THE NEW 5,11-DIHYDRO-6H-DIPIRIDO ARE EXPOSED [3, 2-B; 2``, 3 '' - E] [1,4] DIACEPINES. THEY ARE USED IN THE PREVENTION OR TREATMENT OF HIV INFECTION.

ES90121954T 1989-11-17 1990-11-16 5,11-DIHIDRO-6H-DIPIRIDO (3,2-B: 2 ', 3'-E) (1,4) DIAZEPINES AND ITS USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION. Expired - Lifetime ES2130114T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43892389A 1989-11-17 1989-11-17
US57900190A 1990-09-06 1990-09-06
US60039090A 1990-10-19 1990-10-19

Publications (1)

Publication Number Publication Date
ES2130114T3 true ES2130114T3 (en) 1999-07-01

Family

ID=27412005

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90121954T Expired - Lifetime ES2130114T3 (en) 1989-11-17 1990-11-16 5,11-DIHIDRO-6H-DIPIRIDO (3,2-B: 2 ', 3'-E) (1,4) DIAZEPINES AND ITS USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION.

Country Status (21)

Country Link
EP (1) EP0429987B1 (en)
AP (1) AP179A (en)
AT (1) ATE177744T1 (en)
AU (1) AU630251B2 (en)
CA (1) CA2030056C (en)
DE (2) DE69033003T2 (en)
DK (1) DK0429987T3 (en)
ES (1) ES2130114T3 (en)
FI (1) FI94529C (en)
GR (1) GR3030100T3 (en)
HK (1) HK1011025A1 (en)
IE (1) IE904141A1 (en)
IL (1) IL96367A (en)
LU (1) LU90393I2 (en)
NL (1) NL990022I2 (en)
NO (2) NO175478C (en)
NZ (1) NZ236105A (en)
OA (1) OA09852A (en)
PT (1) PT95919B (en)
RU (1) RU2040527C1 (en)
UA (1) UA34420C2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
US5200522A (en) * 1991-06-11 1993-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for preparing 3-amino-2-chloro-4-alkylpyridines
CA2082801C (en) * 1991-06-11 2003-07-08 Karl G. Grozinger Method for the preparation of 3-amino-2-chloro-4-alkylpyridines
DE4138908A1 (en) * 1991-11-27 1993-06-03 Bayer Ag 6-thiono-dibenz (B, E) azepines
DE4138853A1 (en) * 1991-11-27 1993-06-03 Bayer Ag 5,6-DIHYDRO-DIBENZ (B, E) AZEPINE-6,11-DION-11-OXIME
EP0598396B1 (en) * 1992-11-18 1998-09-02 Boehringer Ingelheim Pharmaceuticals Inc. Improved method for the preparation of 3-Amino-2-chloro-4-alkylpyridines
AU5883794A (en) * 1993-01-20 1994-08-15 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Diazepin derivatives and antiviral compositions
DE4333697A1 (en) * 1993-10-02 1995-04-06 Merck Patent Gmbh Process for the preparation of 3-aminopyridines from 3-nitropyridines
DE4403311C1 (en) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Process for the preparation of nevirapine (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-d iazepin]-6-one)
EP0745083B1 (en) * 1994-02-18 1998-05-20 Boehringer Ingelheim Pharmaceuticals Inc. 2-HETEROARYL-5,11-DIHYDRO-6H-DIPYRIDO [3,2-b:2',3'-e][1,4]DIAZEPINES AND THEIR USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION
US5917033A (en) * 1995-10-31 1999-06-29 University Of Medicine & Dentistry Of New Jersey Structure based design of inhibitors of HIV-1 reverse transcriptase
US5747488A (en) * 1996-01-30 1998-05-05 Boehringer Ingelheim Pharmaceuticals, Inc. 2-aryl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-E! 1, 4!diazepines and their use in the treatment of HIV infection
UA44370C2 (en) * 1997-08-25 2002-02-15 Берінгер Інгельхейм Фармасьютікалз, Інк. PHARMACEUTICAL COMPOSITION THAT INHIBITS HIV-1 REVERSE TRANSCRIPTASE
DE10023492A1 (en) * 2000-05-09 2001-11-22 Schering Ag New 2-(((hetero)aryl-alkyl)-amino)-aza-benzamide derivatives, are VEGF receptor, KDR kinase and FLT kinase inhibitors useful e.g. for treating tumors, psoriasis, arthritis or renal or ophthalmological diseases
US7102009B2 (en) 2001-01-12 2006-09-05 Amgen Inc. Substituted amine derivatives and methods of use
US7105682B2 (en) 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US6878714B2 (en) 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
US7307088B2 (en) 2002-07-09 2007-12-11 Amgen Inc. Substituted anthranilic amide derivatives and methods of use
EP1781300A1 (en) 2004-07-16 2007-05-09 ProteoSys AG Muscarinic antagonists with parp and sir modulatng activity as agents for inflammatory diseases
US8247556B2 (en) 2005-10-21 2012-08-21 Amgen Inc. Method for preparing 6-substituted-7-aza-indoles
AU2008262031B2 (en) 2007-06-08 2011-08-25 Boehringer Ingelheim International Gmbh Extended release formulation of nevirapine
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment
JP2017535573A (en) 2014-11-25 2017-11-30 バイエル ファーマ アクチエンゲゼルシャフト Substituted pyridobenzodiazepinone derivatives and uses thereof
EP3153157A1 (en) 2015-10-09 2017-04-12 Teva Pharmaceutical Works Private Limited Company Pharmaceutical composition for prolonged release of nevirapine
CN107382848A (en) * 2017-07-15 2017-11-24 河北蓝泰化工科技有限公司 A kind of nicotinamide compounds and its preparation method and application

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA783570A (en) * 1968-04-23 Schmidt Gunther 5,6-dihydro-6-oxo-11h-pyrido (2,3-b) (1,4)-benzodiazepines
CA554134A (en) * 1958-03-11 Hoffmann Karl Thia-aza-cycloheptadiene compounds and process for their manufacture
CA658624A (en) * 1963-02-26 Schmutz Jean Diazepine derivatives
DE3643666A1 (en) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K NEW CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF, AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3726908A1 (en) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS
DE3735895A1 (en) * 1987-10-23 1989-05-03 Thomae Gmbh Dr K CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING THESE COMPOUNDS
DE69031845T2 (en) * 1989-04-20 1998-05-07 Boehringer Ingelheim Pharma 6,11-Dihydro-5H-pyrido (2,3-b) (1,5) benzodiazepin-5-one and thione and their use for the prevention or treatment of AIDS
EP0393529B1 (en) * 1989-04-20 1993-06-30 Boehringer Ingelheim Pharmaceuticals Inc. 5,11-dihydro-6H-dipyrido [3,2-b:2',3'-e][1,4]diazepin-6-ones and their use in the prevention or treatment of AIDS
EP0410148B1 (en) * 1989-06-28 1994-04-06 Boehringer Ingelheim Pharmaceuticals Inc. Novel 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-ones and thiones and their use in the prevention or treatment of AIDS

Also Published As

Publication number Publication date
AP179A (en) 1992-04-30
LU90393I2 (en) 1999-06-30
FI905674A (en) 1991-05-18
DK0429987T3 (en) 1999-10-11
ATE177744T1 (en) 1999-04-15
PT95919B (en) 1998-01-30
RU2040527C1 (en) 1995-07-25
UA34420C2 (en) 2001-03-15
CA2030056C (en) 1995-10-17
NZ236105A (en) 1994-04-27
DE19975051I2 (en) 2004-05-06
AP9000224A0 (en) 1991-01-31
NO175478C (en) 1994-10-19
GR3030100T3 (en) 1999-07-30
OA09852A (en) 1994-08-15
IL96367A (en) 1997-02-18
IE904141A1 (en) 1991-05-22
NL990022I2 (en) 2007-11-01
PT95919A (en) 1991-09-13
NL990022I1 (en) 1999-10-01
DE69033003T2 (en) 1999-09-16
AU6673290A (en) 1991-05-23
HK1011025A1 (en) 1999-07-02
EP0429987A3 (en) 1992-01-22
FI94529B (en) 1995-06-15
NO904986D0 (en) 1990-11-16
NO1999013I1 (en) 1999-06-29
DE69033003D1 (en) 1999-04-22
NO175478B (en) 1994-07-11
AU630251B2 (en) 1992-10-22
EP0429987A2 (en) 1991-06-05
NO904986L (en) 1991-05-21
CA2030056A1 (en) 1991-05-18
EP0429987B1 (en) 1999-03-17
FI94529C (en) 1995-09-25
FI905674A0 (en) 1990-11-16

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