DK523476A - Fremgangsmade til fremstilling af n-acyl og carboxyl-derivater af thienamycin - Google Patents
Fremgangsmade til fremstilling af n-acyl og carboxyl-derivater af thienamycinInfo
- Publication number
- DK523476A DK523476A DK523476A DK523476A DK523476A DK 523476 A DK523476 A DK 523476A DK 523476 A DK523476 A DK 523476A DK 523476 A DK523476 A DK 523476A DK 523476 A DK523476 A DK 523476A
- Authority
- DK
- Denmark
- Prior art keywords
- thienamycin
- acyl
- procedure
- preparation
- carboxyl derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63429575A | 1975-11-21 | 1975-11-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK523476A true DK523476A (da) | 1977-05-22 |
Family
ID=24543215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK523476A DK523476A (da) | 1975-11-21 | 1976-11-19 | Fremgangsmade til fremstilling af n-acyl og carboxyl-derivater af thienamycin |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4397861A (nl) |
| JP (1) | JPS5277084A (nl) |
| CH (1) | CH632508A5 (nl) |
| DE (1) | DE2652674A1 (nl) |
| DK (1) | DK523476A (nl) |
| FR (1) | FR2332013A1 (nl) |
| GB (1) | GB1570989A (nl) |
| NL (1) | NL7612941A (nl) |
| SE (1) | SE7612962L (nl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4839352A (en) * | 1975-11-21 | 1989-06-13 | Merck & Co., Inc. | N-acyl derivatives of thienamycin |
| US4235917A (en) * | 1977-05-05 | 1980-11-25 | Merck & Co., Inc. | N-Alkyl-N-acyl derivatives of thienamycin |
| EP0004132A1 (en) * | 1978-03-04 | 1979-09-19 | Beecham Group Plc | Esters of beta-lactam antibiotics, a process for their preparation pharmaceutical compositions containing them and the compounds for use as antibacterial agents |
| JPS565457A (en) * | 1979-06-27 | 1981-01-20 | Dai Ichi Seiyaku Co Ltd | Thienamycin intermediate |
| AU6377980A (en) * | 1979-10-29 | 1981-05-07 | Beecham Group Limited | 1-azabicyclo(3,2,0)hept-2-ene derivatives |
| US4426390A (en) * | 1980-10-01 | 1984-01-17 | Sanraku-Ocean Co., Ltd. | Novel β-lactam compounds, process for producing thereof, and use thereof as medicines |
| DE3277622D1 (en) * | 1981-07-01 | 1987-12-17 | Sanraku Inc | Novel antibiotics and process for production thereof |
| JPS5857392A (ja) * | 1981-10-02 | 1983-04-05 | Sanraku Inc | 新規な抗生物質ｏａ−６１２９のリン酸エステル |
| US4992542A (en) * | 1984-01-24 | 1991-02-12 | Merck & Co., Inc. | 2-substituted-6-carbadethiapen-2-em-3-carboxylic acids |
| US5496816A (en) * | 1994-03-14 | 1996-03-05 | Merck & Co., Inc. | Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1004670A (en) * | 1963-04-23 | 1965-09-15 | Beecham Res Lab | Penicillins |
| GB1348984A (en) * | 1970-06-16 | 1974-03-27 | Merck & Co Inc | Antibiotics and processes for their production |
| US4162324A (en) * | 1975-11-21 | 1979-07-24 | Merck & Co., Inc. | Antibiotics 890A1 and 890A3 |
| US4165379A (en) * | 1975-11-21 | 1979-08-21 | Merck & Co., Inc. | N-acetyl thienamycin |
-
1976
- 1976-11-18 CH CH1455476A patent/CH632508A5/de not_active IP Right Cessation
- 1976-11-19 NL NL7612941A patent/NL7612941A/nl unknown
- 1976-11-19 DE DE19762652674 patent/DE2652674A1/de not_active Ceased
- 1976-11-19 DK DK523476A patent/DK523476A/da unknown
- 1976-11-19 FR FR7634883A patent/FR2332013A1/fr active Granted
- 1976-11-19 GB GB48239/76A patent/GB1570989A/en not_active Expired
- 1976-11-19 SE SE7612962A patent/SE7612962L/xx not_active Application Discontinuation
- 1976-11-22 JP JP51139651A patent/JPS5277084A/ja active Granted
-
1981
- 1981-11-16 US US06/321,497 patent/US4397861A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2332013B1 (nl) | 1978-12-29 |
| US4397861A (en) | 1983-08-09 |
| JPS5277084A (en) | 1977-06-29 |
| DE2652674A1 (de) | 1977-06-02 |
| FR2332013A1 (fr) | 1977-06-17 |
| CH632508A5 (de) | 1982-10-15 |
| SE7612962L (sv) | 1977-05-22 |
| GB1570989A (en) | 1980-07-09 |
| NL7612941A (nl) | 1977-05-24 |
| JPS6259107B2 (nl) | 1987-12-09 |
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