DK489384A - 6alfa-(1-hydroxyethyl)-2-(dioxacycloalkyl)alkylthio-2-penem-3-carboxylsyre-forbindelser og farmaceutisk praeparat - Google Patents

6alfa-(1-hydroxyethyl)-2-(dioxacycloalkyl)alkylthio-2-penem-3-carboxylsyre-forbindelser og farmaceutisk praeparat Download PDF

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Publication number
DK489384A
DK489384A DK489384A DK489384A DK489384A DK 489384 A DK489384 A DK 489384A DK 489384 A DK489384 A DK 489384A DK 489384 A DK489384 A DK 489384A DK 489384 A DK489384 A DK 489384A
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DK
Denmark
Prior art keywords
6alfa
dioxacycloalkyl
penem
alkylthio
hydroxyethyl
Prior art date
Application number
DK489384A
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English (en)
Other versions
DK489384D0 (da
DK166824B1 (da
Inventor
Ernest Seiichi Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK489384D0 publication Critical patent/DK489384D0/da
Publication of DK489384A publication Critical patent/DK489384A/da
Application granted granted Critical
Publication of DK166824B1 publication Critical patent/DK166824B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK489384A 1983-10-14 1984-10-12 2-substituerede 6alfa-(1-hydroxyethyl)-2-penem-3-carboxylsyre-forbindelser og farmaceutisk praeparat indeholdende disse DK166824B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54185483A 1983-10-14 1983-10-14
US54185483 1983-10-14
US06/649,517 US4614737A (en) 1983-10-14 1984-09-13 2-dioxacycloalkylthiopenem derivatives
US64951784 1984-09-13

Publications (3)

Publication Number Publication Date
DK489384D0 DK489384D0 (da) 1984-10-12
DK489384A true DK489384A (da) 1985-04-15
DK166824B1 DK166824B1 (da) 1993-07-19

Family

ID=27066822

Family Applications (1)

Application Number Title Priority Date Filing Date
DK489384A DK166824B1 (da) 1983-10-14 1984-10-12 2-substituerede 6alfa-(1-hydroxyethyl)-2-penem-3-carboxylsyre-forbindelser og farmaceutisk praeparat indeholdende disse

Country Status (10)

Country Link
US (1) US4614737A (da)
EP (1) EP0138538B1 (da)
AU (1) AU552157B2 (da)
CA (1) CA1235117A (da)
DE (1) DE3475621D1 (da)
DK (1) DK166824B1 (da)
GR (1) GR80618B (da)
IE (1) IE57574B1 (da)
IL (1) IL73224A (da)
NZ (1) NZ209867A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772597A (en) * 1983-10-14 1988-09-20 Pfizer Inc. 2-azacycloalkylthiopenem derivatives
JPH075463B2 (ja) * 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
JP2526046B2 (ja) * 1986-12-26 1996-08-21 サントリー株式会社 ペネム誘導体、その製造法およびその用途
US4992543A (en) * 1988-10-19 1991-02-12 Pfizer Inc. Penem derivatives
US4895940A (en) * 1988-10-19 1990-01-23 Pfizer Inc. Process for the preparation of penems
US5191075A (en) * 1988-10-19 1993-03-02 Pfizer Inc Process for the preparation of penems
RU2070555C1 (ru) * 1992-09-09 1996-12-20 Санкио Компани Лимитед Способ получения соединения пенема или карбапенема и соединение карбапенема
JPH09202789A (ja) * 1995-11-20 1997-08-05 Suntory Ltd ペネム誘導体およびこれを含有する抗菌剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid

Also Published As

Publication number Publication date
EP0138538B1 (en) 1988-12-14
DK489384D0 (da) 1984-10-12
EP0138538A1 (en) 1985-04-24
IE842602L (en) 1985-04-14
CA1235117A (en) 1988-04-12
IE57574B1 (en) 1992-12-16
AU3419184A (en) 1985-04-18
NZ209867A (en) 1987-04-30
IL73224A0 (en) 1985-01-31
IL73224A (en) 1988-09-30
GR80618B (en) 1985-02-12
US4614737A (en) 1986-09-30
DE3475621D1 (en) 1989-01-19
AU552157B2 (en) 1986-05-22
DK166824B1 (da) 1993-07-19

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed