DK489378A - 6-oxygenerede-3,20-dioxopregnanderivater samt fremgangsmaade til fremstilling der af og farmaceutiske kompositioner indeholdende disse - Google Patents
6-oxygenerede-3,20-dioxopregnanderivater samt fremgangsmaade til fremstilling der af og farmaceutiske kompositioner indeholdende disseInfo
- Publication number
- DK489378A DK489378A DK489378A DK489378A DK489378A DK 489378 A DK489378 A DK 489378A DK 489378 A DK489378 A DK 489378A DK 489378 A DK489378 A DK 489378A DK 489378 A DK489378 A DK 489378A
- Authority
- DK
- Denmark
- Prior art keywords
- dioxopregnan
- oxygenated
- procedures
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
- C07J71/0068—Nitrogen and oxygen at position 16(17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0073—Sulfur-containing hetero ring
- C07J71/0089—Sulfur-containing hetero ring containing sulfur and oxygen
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/849,563 US4201778A (en) | 1977-11-08 | 1977-11-08 | 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates |
Publications (1)
Publication Number | Publication Date |
---|---|
DK489378A true DK489378A (da) | 1979-05-09 |
Family
ID=25306004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK489378A DK489378A (da) | 1977-11-08 | 1978-11-02 | 6-oxygenerede-3,20-dioxopregnanderivater samt fremgangsmaade til fremstilling der af og farmaceutiske kompositioner indeholdende disse |
Country Status (9)
Country | Link |
---|---|
US (1) | US4201778A (da) |
EP (1) | EP0001864A1 (da) |
JP (1) | JPS5473765A (da) |
AU (1) | AU4127478A (da) |
DK (1) | DK489378A (da) |
FI (1) | FI783340A (da) |
IL (1) | IL55862A0 (da) |
IT (1) | IT1099828B (da) |
ZA (1) | ZA786054B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU572589B2 (en) | 1983-12-14 | 1988-05-12 | Upjohn Company, The | 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids |
US4808610A (en) * | 1986-10-02 | 1989-02-28 | Schering Corporation | Mometasone furoate anti-inflammatory cream composition using hexylene glycol |
US5502076A (en) * | 1994-03-08 | 1996-03-26 | Hoffmann-La Roche Inc. | Dispersing agents for use with hydrofluoroalkane propellants |
US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
US20030129186A1 (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
SI1889198T1 (sl) | 2005-04-28 | 2015-02-27 | Proteus Digital Health, Inc. | Farma-informacijski sistem |
EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
US10231979B2 (en) * | 2015-08-07 | 2019-03-19 | Indiana University Research And Technology Corporation | Modulation of inflammation using progesterone metabolites |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1184505A (fr) * | 1955-06-07 | 1959-07-22 | Scherico Ltd | Procédé de préparation de composés stéroïdes de la série du prégnane |
US3079301A (en) * | 1956-04-25 | 1963-02-26 | Schering Corp | 9alpha-halo-1, 4, 6-pregnatrienes and therapeutic compositions containing same |
US2816902A (en) * | 1957-01-14 | 1957-12-17 | Schering Corp | Hydroxylated steroids |
US2937975A (en) * | 1958-08-18 | 1960-05-24 | Pfizer & Co C | Steroid halohydrins and process therefor |
US2887499A (en) * | 1958-11-13 | 1959-05-19 | Schering Corp | Hydroxylated steroid intermediates and methods for their manufacture |
US3032565A (en) * | 1960-08-24 | 1962-05-01 | Searle & Co | Process for the manufacture of 6-alkoxy-and 6-keto steroids and compounds obtained thereby |
US3071580A (en) * | 1961-04-28 | 1963-01-01 | American Cyanamid Co | 6beta-hydroxy-16alpha, 17alpha-alkylidendioxy-11-oxygenated pregnenes |
US3131181A (en) * | 1961-05-29 | 1964-04-28 | American Cyanamid Co | Method of preparing 6-hydroxy pregnenes and pregnadienes and products resulting therefrom |
US3629303A (en) * | 1969-06-09 | 1971-12-21 | Schering Corp | 6-alkoxy - 16 - alkylidene - 17alpha - lower alkanoyloxy-21-desoxy - 4 6 - pregnadienes methods for their manufacture and intermediates produced thereby |
DE2512915A1 (de) * | 1974-03-27 | 1975-10-09 | Plurichemie Anstalt | 16-methyl-9 alpha-halogen-steroide ester, aether und verfahren zu ihrer herstellung |
US4076708A (en) * | 1976-12-22 | 1978-02-28 | Schering Corporation | Process for the preparation of 7α-halogeno-3-oxo-4-dehydro steroids and novel 7α-halogeno derivatives produced thereby |
-
1977
- 1977-11-08 US US05/849,563 patent/US4201778A/en not_active Expired - Lifetime
-
1978
- 1978-10-26 ZA ZA00786054A patent/ZA786054B/xx unknown
- 1978-10-26 IT IT29133/78A patent/IT1099828B/it active
- 1978-10-31 EP EP78200275A patent/EP0001864A1/en not_active Withdrawn
- 1978-11-02 AU AU41274/78A patent/AU4127478A/en active Pending
- 1978-11-02 JP JP13570378A patent/JPS5473765A/ja active Pending
- 1978-11-02 FI FI783340A patent/FI783340A/fi unknown
- 1978-11-02 DK DK489378A patent/DK489378A/da unknown
- 1978-11-03 IL IL55862A patent/IL55862A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FI783340A (fi) | 1979-05-09 |
JPS5473765A (en) | 1979-06-13 |
IL55862A0 (en) | 1979-01-31 |
ZA786054B (en) | 1979-10-31 |
IT1099828B (it) | 1985-09-28 |
IT7829133A0 (it) | 1978-10-26 |
AU4127478A (en) | 1979-05-17 |
EP0001864A1 (en) | 1979-05-16 |
US4201778A (en) | 1980-05-06 |
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