DK488287A - PHARMACEUTICAL PREPARATION - Google Patents

PHARMACEUTICAL PREPARATION

Info

Publication number
DK488287A
DK488287A DK488287A DK488287A DK488287A DK 488287 A DK488287 A DK 488287A DK 488287 A DK488287 A DK 488287A DK 488287 A DK488287 A DK 488287A DK 488287 A DK488287 A DK 488287A
Authority
DK
Denmark
Prior art keywords
units
density
dosage form
pharmaceutical preparation
pharmaceutical
Prior art date
Application number
DK488287A
Other languages
Danish (da)
Other versions
DK488287D0 (en
Inventor
John Michael Newton
Jane Elizabeth Devereux
Original Assignee
London Pharmacy Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868622482A external-priority patent/GB8622482D0/en
Priority claimed from GB878708011A external-priority patent/GB8708011D0/en
Application filed by London Pharmacy Innovation filed Critical London Pharmacy Innovation
Publication of DK488287D0 publication Critical patent/DK488287D0/en
Publication of DK488287A publication Critical patent/DK488287A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The residence time in the human stomach of pharmaceutical, gastric controlled release, solid units can be increased significantly if the units have a density that is much higher than normal. A preferred oral dosage form according to the invention comprises a capsule or other dosage form having a dimension above 2mm and that contains one or more of the said units. The density of each unit is preferably at least 2.5 and usually at least 2.7g/ml and can conveniently be achieved by including at least 50% by weight of a weighting agent such as barium sulphate.
DK488287A 1986-09-18 1987-09-17 PHARMACEUTICAL PREPARATION DK488287A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868622482A GB8622482D0 (en) 1986-09-18 1986-09-18 Pharmaceutical formulation
GB878708011A GB8708011D0 (en) 1987-04-03 1987-04-03 Pharmaceutical formulation

Publications (2)

Publication Number Publication Date
DK488287D0 DK488287D0 (en) 1987-09-17
DK488287A true DK488287A (en) 1988-03-19

Family

ID=26291305

Family Applications (1)

Application Number Title Priority Date Filing Date
DK488287A DK488287A (en) 1986-09-18 1987-09-17 PHARMACEUTICAL PREPARATION

Country Status (19)

Country Link
US (1) US4938967A (en)
EP (1) EP0265061B1 (en)
KR (1) KR890004686B1 (en)
AT (1) ATE71293T1 (en)
AU (1) AU606353B2 (en)
BE (1) BE1000616A5 (en)
CA (1) CA1302259C (en)
CH (1) CH674146A5 (en)
DE (1) DE3775880D1 (en)
DK (1) DK488287A (en)
ES (1) ES2038669T3 (en)
FR (1) FR2604090B1 (en)
GB (1) GB2196252B (en)
GR (1) GR3004268T3 (en)
HU (1) HU202101B (en)
IL (1) IL83897A (en)
IT (1) IT1211484B (en)
NZ (1) NZ221805A (en)
PT (1) PT85747B (en)

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US5374430A (en) * 1986-09-18 1994-12-20 London School Of Pharmacy Pharmaceutical formulation
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IE63986B1 (en) * 1989-12-30 1995-06-28 Akzo Nv Pharmaceutical preparation for oral administration in fluid form
DK165090D0 (en) * 1990-07-09 1990-07-09 Kem En Tec As CONLOMERATED PARTICLES
GB9018839D0 (en) * 1990-08-29 1990-10-10 Newton John M Slow release compositions
US5166145A (en) * 1990-09-10 1992-11-24 Alza Corporation Antiemetic therapy
SE9101149D0 (en) 1991-04-17 1991-04-17 Pharmacia Lkb Biotech BEADS FOR DOWN STREAM PROCESSING
US5198229A (en) * 1991-06-05 1993-03-30 Alza Corporation Self-retaining gastrointestinal delivery device
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5288505A (en) * 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
IT1251153B (en) * 1991-08-06 1995-05-04 Vectorpharma Int SOLID PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION HAVING PROHIBITED GASTRIC RESIDENCE
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
MX9304638A (en) * 1992-07-31 1994-05-31 Neose Pharm Inc COMPOSITION TO TREAT AND INHIBIT GASTRIC AND DUODENAL ULCERS.
WO1994003184A1 (en) * 1992-07-31 1994-02-17 Neose Pharmaceuticals, Inc. Compositions for treating and inhibiting gastric and duodenal ulcers
EP0654038B1 (en) * 1992-08-04 1999-11-10 James M. Dunn Controlled release pharmaceutical formulations of 3'-azido-3'-deoxythymidine and methods of use
FR2703908B1 (en) * 1993-04-13 1995-06-02 Asta Medica Ag Pharmaceutical form for rectal administration of pharmacologically active compounds.
US6706188B2 (en) 1993-05-03 2004-03-16 Amersham Biociences Ab Process and means for down stream processing
US8828432B2 (en) * 1996-10-28 2014-09-09 General Mills, Inc. Embedding and encapsulation of sensitive components into a matrix to obtain discrete controlled release particles
US7179486B1 (en) 1997-04-01 2007-02-20 Nostrum Pharmaceuticals, Inc. Process for preparing sustained release tablets
DK1065936T3 (en) * 1998-03-23 2009-11-02 Gen Mills Inc Encapsulation of constituents in edible products
US8636648B2 (en) 1999-03-01 2014-01-28 West View Research, Llc Endoscopic smart probe
US10973397B2 (en) 1999-03-01 2021-04-13 West View Research, Llc Computerized information collection and processing apparatus
US20040101540A1 (en) * 1999-09-01 2004-05-27 John Cooker Oral delivery system and method for making same
US20050079214A1 (en) * 1999-09-01 2005-04-14 John Cooker Oral delivery system and method for making same
JP2003508420A (en) 1999-09-02 2003-03-04 ノストラム・ファーマスーティカルズ・インコーポレイテッド Controlled release oral dose suitable for oral administration
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
AU2001257359A1 (en) 2000-04-27 2001-11-07 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
DE10031043A1 (en) 2000-06-26 2002-02-14 Bayer Ag Retarded preparations of quinolone antibiotics and process for their preparation
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
FI121528B (en) * 2000-10-30 2010-12-31 Biohit Oyj Pharmaceutical composition to reduce the risk of sunk in cancer by binding acetaldehyde in saliva, stomach and colon
US20110171296A1 (en) * 2000-10-30 2011-07-14 Biohit Oyj Method and preparation for binding acetaldehyde in saliva, the stomach and the large intestine
US6569808B2 (en) * 2001-07-30 2003-05-27 Lee F. Klinger Methods and compositions useful for bryophyte remediation to improve forest health and growth
AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
US7094369B2 (en) 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7131997B2 (en) 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
GB0214013D0 (en) * 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
US20040076582A1 (en) * 2002-08-30 2004-04-22 Dimatteo Kristian Agent delivery particle
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US20070102672A1 (en) * 2004-12-06 2007-05-10 Hamilton Judd D Ceramic radiation shielding material and method of preparation
JPWO2006080481A1 (en) * 2005-01-31 2008-06-19 杏林製薬株式会社 Multiple unit type oral sustained-release preparation and method for producing the same
US20070087056A1 (en) * 2005-08-09 2007-04-19 Claudia Guthmann Pharmaceutical form with sustained pH-independent active ingredient release for active ingredients having strong pH-dependent solubility
US7803413B2 (en) 2005-10-31 2010-09-28 General Mills Ip Holdings Ii, Llc. Encapsulation of readily oxidizable components
US8512761B2 (en) 2006-01-27 2013-08-20 Yale University Fast acting inhibitor of gastric acid secretion
US11510894B2 (en) 2006-01-27 2022-11-29 John P. Geibel Fast acting inhibitor of gastric acid secretion
US20090104243A1 (en) * 2007-09-07 2009-04-23 Qlt Plug Delivery, Inc. - Qpdi Drug cores for sustained release of therapeutic agents
US20100021607A1 (en) * 2008-07-22 2010-01-28 Van Lengerich Bernhard H Fruit products containing omega-3 fatty acids
BRPI1009121A2 (en) * 2009-03-04 2018-06-19 Orexo Ab abuse resistant formulations
CN102421419B (en) 2009-05-08 2016-05-04 奥瑞克索股份公司 For continuing the composition that comprises geopolymer adhesive of drug delivery
US20100310728A1 (en) * 2009-06-05 2010-12-09 General Mills, Inc. Encapsulated omega-3 fatty acids for baked goods production
WO2012032337A2 (en) 2010-09-07 2012-03-15 Orexo Ab A transdermal drug administration device
US20170172946A1 (en) * 2015-12-21 2017-06-22 Stephan Hau Micro-solid phase extraction

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CA614091A (en) * 1956-11-05 1961-02-07 Commonwealth Scientific And Industrial Research Organization Time delay pill for ruminant
GB936386A (en) * 1959-01-16 1963-09-11 Wellcome Found Pellets for supplying biologically active substances to ruminants
CH582002A5 (en) * 1972-06-09 1976-11-30 Purdue Research Foundation
GB1590573A (en) * 1976-08-06 1981-06-03 Atomic Energy Authority Uk Biologically active gels
GB1590574A (en) * 1976-08-06 1981-06-03 Atomic Energy Authority Uk Biologically active gels
GB1576376A (en) * 1977-03-30 1980-10-08 Benzon As Alfred Multiple-unit drug dose
GB2015875B (en) * 1978-02-24 1982-10-20 Novex Foreign Trade Co Ltd Solid oral pharaceutical product with increased efficacy and predetermined steady state of solubility
JPS6024767B2 (en) * 1979-08-24 1985-06-14 塩野義製薬株式会社 enteric-coated hard capsules
PL124267B1 (en) * 1979-09-12 1983-01-31 Lilly Co Eli Device for use in the masseter/galea part of a ruminant's gaster
GB2100602B (en) * 1981-06-24 1984-11-14 May & Baker Ltd Device for delivering biologically active substances to the digestive tract.
ZA825384B (en) * 1981-07-31 1983-05-25 Tillott J B Ltd Orally administrable pharmaceutical compositions
GB2123690A (en) * 1982-07-20 1984-02-08 Nat Res Dev Sustained release device
GB2123693B (en) * 1982-07-20 1987-05-13 Nat Res Dev Sustained release device
DE3306250A1 (en) * 1983-02-23 1984-08-23 Basf Ag, 6700 Ludwigshafen SPHERICAL SINGLE CRYSTALS FOR PHARMACEUTICAL PURPOSES
FR2560768A1 (en) * 1984-03-07 1985-09-13 Crb Virbac Sa PROGRAMMED RELEASE DEVICE
DE3431861A1 (en) * 1984-08-30 1986-03-13 Troponwerke GmbH & Co KG, 5000 Köln PELLET PREPARATION
US4609374A (en) * 1985-04-22 1986-09-02 Alza Corporation Osmotic device comprising means for governing initial time of agent release therefrom

Also Published As

Publication number Publication date
CA1302259C (en) 1992-06-02
ATE71293T1 (en) 1992-01-15
GB2196252A (en) 1988-04-27
HU202101B (en) 1991-02-28
KR890004686B1 (en) 1989-11-25
AU7848187A (en) 1988-03-24
GR3004268T3 (en) 1993-03-31
DK488287D0 (en) 1987-09-17
HUT45194A (en) 1988-06-28
AU606353B2 (en) 1991-02-07
EP0265061A1 (en) 1988-04-27
GB8721186D0 (en) 1987-10-14
KR880003617A (en) 1988-05-28
BE1000616A5 (en) 1989-02-21
DE3775880D1 (en) 1992-02-20
IL83897A0 (en) 1988-02-29
FR2604090A1 (en) 1988-03-25
PT85747A (en) 1987-10-01
PT85747B (en) 1991-02-08
EP0265061B1 (en) 1992-01-08
ES2038669T3 (en) 1993-08-01
FR2604090B1 (en) 1990-06-15
IT8767796A0 (en) 1987-09-17
US4938967A (en) 1990-07-03
CH674146A5 (en) 1990-05-15
NZ221805A (en) 1991-02-26
IL83897A (en) 1991-06-10
GB2196252B (en) 1990-10-17
IT1211484B (en) 1989-11-03

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Legal Events

Date Code Title Description
A0 Application filed
AHB Application shelved due to non-payment