DK464275A - Fremgangsmade til fremstilling af carboxylsyrer og estere afledt af vinblastin, vincristin og leurosidin - Google Patents
Fremgangsmade til fremstilling af carboxylsyrer og estere afledt af vinblastin, vincristin og leurosidinInfo
- Publication number
- DK464275A DK464275A DK464275A DK464275A DK464275A DK 464275 A DK464275 A DK 464275A DK 464275 A DK464275 A DK 464275A DK 464275 A DK464275 A DK 464275A DK 464275 A DK464275 A DK 464275A
- Authority
- DK
- Denmark
- Prior art keywords
- leurosidin
- vincristin
- vinblastin
- procedure
- preparation
- Prior art date
Links
- 150000001735 carboxylic acids Chemical class 0.000 title 1
- JXLYSJRDGCGARV-CFWMRBGOSA-N vinblastine Chemical compound C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-CFWMRBGOSA-N 0.000 title 1
- 229960003048 vinblastine Drugs 0.000 title 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 title 1
- 229960004528 vincristine Drugs 0.000 title 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/515,134 US4012390A (en) | 1974-10-16 | 1974-10-16 | Vinblastinoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK464275A true DK464275A (da) | 1976-04-17 |
Family
ID=24050111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK464275A DK464275A (da) | 1974-10-16 | 1975-10-15 | Fremgangsmade til fremstilling af carboxylsyrer og estere afledt af vinblastin, vincristin og leurosidin |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4012390A ( ) |
| JP (1) | JPS5186500A ( ) |
| AR (1) | AR208330A1 ( ) |
| AU (1) | AU8556275A ( ) |
| BE (1) | BE834364A ( ) |
| CA (1) | CA1061785A ( ) |
| CH (1) | CH618983A5 ( ) |
| DD (1) | DD122538A5 ( ) |
| DE (1) | DE2544843A1 ( ) |
| DK (1) | DK464275A ( ) |
| ES (1) | ES441860A1 ( ) |
| FR (1) | FR2287905A1 ( ) |
| GB (1) | GB1521053A ( ) |
| HU (1) | HU174569B ( ) |
| IE (1) | IE42132B1 ( ) |
| IL (1) | IL48257A ( ) |
| NL (1) | NL7512120A ( ) |
| SE (1) | SE7511570L ( ) |
| ZA (1) | ZA756424B ( ) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4096148A (en) * | 1976-12-06 | 1978-06-20 | Eli Lilly And Company | Oxazolidinedione derivatives of Vinca alkaloids |
| US4558053A (en) * | 1983-12-21 | 1985-12-10 | Eli Lilly And Company | Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids |
| EP1235598A2 (en) * | 1999-11-12 | 2002-09-04 | Angiotech Pharmaceuticals, Inc. | Compositions of a combination of radioactive therapy and cell-cycle inhibitors |
| WO2004060346A2 (en) | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3392173A (en) * | 1964-03-09 | 1968-07-09 | Lilly Co Eli | Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation |
| US3352868A (en) * | 1964-04-01 | 1967-11-14 | Lilly Co Eli | Dihydrovinblastine |
| US3387001A (en) * | 1964-10-19 | 1968-06-04 | Lilly Co Eli | Novel aminoacyl esters of desacetyl vincaleukoblastine |
-
1974
- 1974-10-16 US US05/515,134 patent/US4012390A/en not_active Expired - Lifetime
-
1975
- 1975-01-01 AR AR260695A patent/AR208330A1/es active
- 1975-10-06 CA CA237,066A patent/CA1061785A/en not_active Expired
- 1975-10-07 IL IL48257A patent/IL48257A/xx unknown
- 1975-10-07 DE DE19752544843 patent/DE2544843A1/de not_active Withdrawn
- 1975-10-08 AU AU85562/75A patent/AU8556275A/en not_active Expired
- 1975-10-10 IE IE2215/75A patent/IE42132B1/en unknown
- 1975-10-10 FR FR7531159A patent/FR2287905A1/fr active Granted
- 1975-10-10 BE BE1006943A patent/BE834364A/xx unknown
- 1975-10-13 JP JP50123730A patent/JPS5186500A/ja active Pending
- 1975-10-13 ZA ZA756424A patent/ZA756424B/xx unknown
- 1975-10-13 GB GB41775/75A patent/GB1521053A/en not_active Expired
- 1975-10-15 DD DD188873A patent/DD122538A5/xx unknown
- 1975-10-15 HU HU75EI652A patent/HU174569B/hu unknown
- 1975-10-15 DK DK464275A patent/DK464275A/da unknown
- 1975-10-15 CH CH1338075A patent/CH618983A5/de not_active IP Right Cessation
- 1975-10-15 NL NL7512120A patent/NL7512120A/xx not_active Application Discontinuation
- 1975-10-15 SE SE7511570A patent/SE7511570L/xx unknown
- 1975-10-16 ES ES441860A patent/ES441860A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5186500A (en) | 1976-07-29 |
| AU8556275A (en) | 1977-04-21 |
| US4012390A (en) | 1977-03-15 |
| NL7512120A (nl) | 1976-04-21 |
| IL48257A0 (en) | 1975-12-31 |
| SE7511570L (sv) | 1976-04-20 |
| CH618983A5 ( ) | 1980-08-29 |
| FR2287905A1 (fr) | 1976-05-14 |
| ES441860A1 (es) | 1977-08-16 |
| AR208330A1 (es) | 1976-12-20 |
| ZA756424B (en) | 1977-05-25 |
| CA1061785A (en) | 1979-09-04 |
| BE834364A (fr) | 1976-04-12 |
| IL48257A (en) | 1979-01-31 |
| GB1521053A (en) | 1978-08-09 |
| DE2544843A1 (de) | 1976-04-29 |
| DD122538A5 ( ) | 1976-10-12 |
| IE42132B1 (en) | 1980-06-04 |
| FR2287905B1 ( ) | 1978-11-10 |
| HU174569B (hu) | 1980-02-28 |
| IE42132L (en) | 1976-04-16 |
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