DK446483A - Fremgangsmaade til fremstilling af 6-substituerede quinolin-5,8-quinoner - Google Patents

Fremgangsmaade til fremstilling af 6-substituerede quinolin-5,8-quinoner Download PDF

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Publication number
DK446483A
DK446483A DK446483A DK446483A DK446483A DK 446483 A DK446483 A DK 446483A DK 446483 A DK446483 A DK 446483A DK 446483 A DK446483 A DK 446483A DK 446483 A DK446483 A DK 446483A
Authority
DK
Denmark
Prior art keywords
quinon
preparing
procedure
substituted quinolin
quinolin
Prior art date
Application number
DK446483A
Other languages
Danish (da)
English (en)
Other versions
DK446483D0 (da
Inventor
Jerome Herbert Fleisch
Winston Stanley Marshall
George Joseph Cullinan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK446483D0 publication Critical patent/DK446483D0/da
Publication of DK446483A publication Critical patent/DK446483A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK446483A 1982-09-30 1983-09-29 Fremgangsmaade til fremstilling af 6-substituerede quinolin-5,8-quinoner DK446483A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/430,895 US4492704A (en) 1982-09-30 1982-09-30 Quinoline quinones and anti-asthmatic use thereof

Publications (2)

Publication Number Publication Date
DK446483D0 DK446483D0 (da) 1983-09-29
DK446483A true DK446483A (da) 1984-03-31

Family

ID=23709535

Family Applications (1)

Application Number Title Priority Date Filing Date
DK446483A DK446483A (da) 1982-09-30 1983-09-29 Fremgangsmaade til fremstilling af 6-substituerede quinolin-5,8-quinoner

Country Status (10)

Country Link
US (1) US4492704A (de)
EP (1) EP0107367B1 (de)
JP (1) JPS5982367A (de)
KR (1) KR840006207A (de)
CA (1) CA1211110A (de)
DE (1) DE3380304D1 (de)
DK (1) DK446483A (de)
GB (1) GB2127814A (de)
GR (1) GR78721B (de)
IL (1) IL69818A0 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576949A (en) * 1984-05-07 1986-03-18 The Upjohn Company Use of 5,6,7,8-tetrahydroquinolines and 5,6-dihydropyrindines as leukotriene and lipoxygenase inhibitors and the novel 3-substituted compounds therein
CA1285951C (en) * 1985-10-28 1991-07-09 Raj N. Misra Naphthalenyl- and quinolinyl-amino substituted phenols
US4692449A (en) * 1986-06-20 1987-09-08 American Cyanamid Company Substituted quinolinediones
US4963565A (en) * 1986-07-30 1990-10-16 National Jewish Center For Immunology And Respiratory Medicine In vivo treatment of mycobacterial infections with 6-cyclo octylamino-5,8-quinoline quinone
US5120843A (en) * 1987-04-27 1992-06-09 Upjohn Pharmaceutically active amines
KR20030038282A (ko) * 2001-11-06 2003-05-16 주식회사 켐온 6-아닐리노퀴놀린-5,8-퀴논을 유효성분으로 함유하는혈관생성 억제제
EP1398031A1 (de) * 2002-09-06 2004-03-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verwendung von 6-Amino-Chinolin-5,8-chinonen und Seneszent-assoziierten Nukleinsäuren zur Behandlung von Tumoren
WO2004098601A1 (en) * 2003-05-06 2004-11-18 Chemon Inc. As a pkc inhibitor, inhibitor for angiogenesis containing 6-anilinoquinoline-5,8-quinone as an effective ingredient
US20120022070A1 (en) * 2008-10-06 2012-01-26 Emory University Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use
WO2017155991A1 (en) * 2016-03-08 2017-09-14 The Regents Of The University Of Michigan Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity
US10550135B2 (en) 2016-03-30 2020-02-04 Council Of Scientific & Industrial Research Silicon incorporated quinolines with anti-malarial and anti-toxoplasmosis activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002310B1 (de) * 1977-11-10 1981-06-24 Beecham Group Plc 4,9-Dihydro-4,9-dioxo-1H-naphtho(2,3-d) triazole, ihre Herstellung und sie enthaltende antiallergische Zusammensetzungen

Also Published As

Publication number Publication date
GR78721B (de) 1984-10-02
GB2127814A (en) 1984-04-18
IL69818A0 (en) 1983-12-30
GB8325678D0 (en) 1983-10-26
DK446483D0 (da) 1983-09-29
EP0107367A3 (en) 1985-05-15
KR840006207A (ko) 1984-11-22
DE3380304D1 (en) 1989-09-07
EP0107367A2 (de) 1984-05-02
CA1211110A (en) 1986-09-09
JPS5982367A (ja) 1984-05-12
US4492704A (en) 1985-01-08
EP0107367B1 (de) 1989-08-02

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment