DK412789D0 - PROCEDURE AND DEVICE FOR FULLY AUTOMATIC SIMULTAN SYNTHESIS OF MULTIPLE POLYPEPTIDES - Google Patents

PROCEDURE AND DEVICE FOR FULLY AUTOMATIC SIMULTAN SYNTHESIS OF MULTIPLE POLYPEPTIDES

Info

Publication number
DK412789D0
DK412789D0 DK412789A DK412789A DK412789D0 DK 412789 D0 DK412789 D0 DK 412789D0 DK 412789 A DK412789 A DK 412789A DK 412789 A DK412789 A DK 412789A DK 412789 D0 DK412789 D0 DK 412789D0
Authority
DK
Denmark
Prior art keywords
synthesis
simultan
procedure
fully automatic
multiple polypeptides
Prior art date
Application number
DK412789A
Other languages
Danish (da)
Other versions
DK412789A (en
DK173633B1 (en
Inventor
Gerd Schnorrenberg
Wilhelm Knapp
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK412789D0 publication Critical patent/DK412789D0/en
Publication of DK412789A publication Critical patent/DK412789A/en
Application granted granted Critical
Publication of DK173633B1 publication Critical patent/DK173633B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00423—Means for dispensing and evacuation of reagents using filtration, e.g. through porous frits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/0059—Sequential processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Abstract

Process and apparatus for the completely automatic simultaneous synthesis of several polypeptides, where up to 96 different polypeptides are synthesised by the solid-phase synthetic method in a robot pipetter.
DK198904127A 1988-08-23 1989-08-22 Method and cannula for pipetting robot for fully automatic simultaneous synthesis of multiple polypeptides DK173633B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3828576 1988-08-23
DE3828576A DE3828576A1 (en) 1988-08-23 1988-08-23 METHOD AND DEVICE FOR THE FULLY AUTOMATIC SIMULTANEOUS SYNTHESIS OF SEVERAL POLYPEPTIDES

Publications (3)

Publication Number Publication Date
DK412789D0 true DK412789D0 (en) 1989-08-22
DK412789A DK412789A (en) 1990-02-24
DK173633B1 DK173633B1 (en) 2001-05-14

Family

ID=6361418

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198904127A DK173633B1 (en) 1988-08-23 1989-08-22 Method and cannula for pipetting robot for fully automatic simultaneous synthesis of multiple polypeptides

Country Status (8)

Country Link
EP (1) EP0355582B1 (en)
JP (1) JPH02167297A (en)
AT (1) ATE82983T1 (en)
AU (1) AU626315B2 (en)
DE (3) DE8816749U1 (en)
DK (1) DK173633B1 (en)
ES (1) ES2036309T3 (en)
GR (1) GR3006611T3 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4005518A1 (en) * 1990-02-22 1991-08-29 Boehringer Ingelheim Kg METHOD AND DEVICE FOR SIMULTANEOUS SYNTHESIS OF SEVERAL POLYPEPTIDES
JPH0720546B2 (en) * 1991-08-26 1995-03-08 株式会社島津製作所 Multi-item simultaneous chemical reactor
US5714127A (en) * 1992-10-08 1998-02-03 Warner-Lambert Company System for multiple simultaneous synthesis
US5324483B1 (en) * 1992-10-08 1996-09-24 Warner Lambert Co Apparatus for multiple simultaneous synthesis
US5567391A (en) * 1992-10-08 1996-10-22 Warner-Lambert Company Apparatus for multiple simultaneous synthesis
US5702672A (en) * 1992-10-08 1997-12-30 Warner-Lambert Company Apparatus and method for multiple simultaneous synthesis
JPH06220084A (en) * 1993-01-23 1994-08-09 Shimadzu Corp Peptide synthesizer
WO1996030393A1 (en) * 1995-03-27 1996-10-03 Warner-Lambert Company A method for the synthesis of mixtures of compounds
DE19844988A1 (en) * 1998-09-30 2000-04-13 Stefan Seeger Parallel solid phase synthesis
WO2000055182A1 (en) * 1999-03-15 2000-09-21 Sankyo Company, Limited Method for synthesizing peptide
US7272175B2 (en) * 2001-08-16 2007-09-18 Dsp Group Inc. Digital phase locked loop

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985032A (en) * 1975-11-13 1976-10-12 Centaur Chemical Co. Micropipette filter tips
US4059020A (en) * 1976-09-09 1977-11-22 Centaur Chemical Co. Filter for micropipettes
FR2485003A1 (en) * 1980-06-23 1981-12-24 Clin Midy AUTOMATED APPARATUS FOR USE IN THE SYNTHESIS OF SOLID-STATE PEPTIDES
FR2582655B1 (en) * 1985-06-03 1988-12-23 Centre Nat Rech Scient SOLID PHASE SEMI-AUTOMATIC PEPTIDE MULTI-SYNTHESIZER
DE3631662A1 (en) * 1986-09-17 1988-03-24 Biotechnolog Forschung Gmbh METHOD FOR SIMULTANEOUS SYNTHESIS OF SEVERAL PEPTIDES ON A SOLID PHASE

Also Published As

Publication number Publication date
DE8816749U1 (en) 1990-05-10
AU626315B2 (en) 1992-07-30
EP0355582B1 (en) 1992-12-02
EP0355582A2 (en) 1990-02-28
JPH02167297A (en) 1990-06-27
ATE82983T1 (en) 1992-12-15
DE3828576C2 (en) 1990-11-22
GR3006611T3 (en) 1993-06-30
AU4013089A (en) 1990-03-01
EP0355582A3 (en) 1990-11-22
DE3828576A1 (en) 1990-03-08
ES2036309T3 (en) 1993-05-16
DK412789A (en) 1990-02-24
DE58902869D1 (en) 1993-01-14
DK173633B1 (en) 2001-05-14

Similar Documents

Publication Publication Date Title
DE3851640D1 (en) Apparatus for gripping plant bales.
DK0489158T3 (en) Method and apparatus for producing organic fertilizers
DK0401844T3 (en) Resorbable moldings and processes for making them
DK23684D0 (en) PROCEDURE FOR SIMILAR SYNTHESIS OF MULTIPLE PHASE OIGONUCLEOTIDES AND APPARATUS FOR EXERCISING THE PROCEDURE
DE3786777T2 (en) Device for producing instruction leaflets.
DK412789D0 (en) PROCEDURE AND DEVICE FOR FULLY AUTOMATIC SIMULTAN SYNTHESIS OF MULTIPLE POLYPEPTIDES
DE3854094D1 (en) Apparatus for operating a semiconductor laser device.
DE3869434D1 (en) APPARATUS FOR UNCORNING A BOTTLE.
DE3481412D1 (en) APPARATUS FOR PRODUCING LABELS.
ZA894478B (en) Centering apparatus for a gemstone
GB8921940D0 (en) Apparatus for culturing plants
DE3878768T2 (en) APPARATUS FOR SETTING A FILM TAPE UNDER TENSION.
DK165289C (en) PROCEDURE AND APPARATUS FOR TEMPORARY SELECTION OF AN OBJECTS FROM A RANGE OF A TRANSPORTER
DK580089D0 (en) APPARATUS FOR MATERIAL SUPPLY TO A PLANT
DE3861515D1 (en) MOLDING PLANT WITH SEVERAL CHILLERS FOR MOLDING STRINGS WITH DIFFERENT DIAMETERS.
GB8823533D0 (en) Method & apparatus for effecting bioreaction
DE3869863D1 (en) DEVICE FOR LABELING BLOW-MOLDED OBJECTS.
DE68911783D1 (en) Process for growing citrus.
DE69131983T2 (en) METHOD AND DEVICE FOR PRODUCING SINGLE-CRYSTAL SEMICONDUCTORS WITH A HIGH SPLIT DISSOR PART
GB8807068D0 (en) Apparatus & method for heating sample
DE69021573D1 (en) METHOD FOR CONCENTRATING OXYGEN 18 WITH A LASER.
DK382085D0 (en) METHOD AND APPARATUS FOR PREPARING A TEMPERATURE COAGULATE
DD259062B1 (en) PROCESS FOR AETZING A (III) B (V) SEMICONDUCTORS
GB8814797D0 (en) Apparatus & method for temperature cycling
NO940887D0 (en) Method and apparatus for sealing a gable top container

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired