DK3923973T3 - Langtidsvirkende g-csf til forebyggelse af neutropeni eller reduktion af varigheden af neutropeni - Google Patents
Langtidsvirkende g-csf til forebyggelse af neutropeni eller reduktion af varigheden af neutropeni Download PDFInfo
- Publication number
- DK3923973T3 DK3923973T3 DK20702699.8T DK20702699T DK3923973T3 DK 3923973 T3 DK3923973 T3 DK 3923973T3 DK 20702699 T DK20702699 T DK 20702699T DK 3923973 T3 DK3923973 T3 DK 3923973T3
- Authority
- DK
- Denmark
- Prior art keywords
- neutropenai
- neutropeania
- csf
- prevention
- duration
- Prior art date
Links
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 title 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962804988P | 2019-02-13 | 2019-02-13 | |
PCT/IB2020/050447 WO2020165664A1 (en) | 2019-02-13 | 2020-01-21 | A long-acting g-csf for preventing neutropenia or reducing duration of neutropenia |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3923973T3 true DK3923973T3 (da) | 2023-04-24 |
Family
ID=69375655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK20702699.8T DK3923973T3 (da) | 2019-02-13 | 2020-01-21 | Langtidsvirkende g-csf til forebyggelse af neutropeni eller reduktion af varigheden af neutropeni |
Country Status (10)
Country | Link |
---|---|
US (1) | US11813310B2 (da) |
EP (1) | EP3923973B1 (da) |
KR (1) | KR20210127215A (da) |
AU (1) | AU2020220651A1 (da) |
BR (1) | BR112021015428A2 (da) |
CA (1) | CA3130032C (da) |
DK (1) | DK3923973T3 (da) |
EA (1) | EA202192241A1 (da) |
ES (1) | ES2943312T3 (da) |
WO (1) | WO2020165664A1 (da) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012044921A1 (en) | 2010-10-01 | 2012-04-05 | St. Jude Children's Research Hospital | Methods and compositions for typing molecular subgroups of medulloblastoma |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8504099D0 (en) | 1985-02-18 | 1985-03-20 | Wellcome Found | Physiologically active substances |
US5214132A (en) | 1986-12-23 | 1993-05-25 | Kyowa Hakko Kogyo Co., Ltd. | Polypeptide derivatives of human granulocyte colony stimulating factor |
US6797493B2 (en) * | 2001-10-01 | 2004-09-28 | Lee-Hwei K. Sun | Fc fusion proteins of human granulocyte colony-stimulating factor with increased biological activities |
KR101380732B1 (ko) | 2007-05-30 | 2014-04-10 | 포항공과대학교 산학협력단 | 면역글로불린 융합 단백질 |
RU2519031C1 (ru) * | 2010-01-19 | 2014-06-10 | Ханми Сайенс Ко., Лтд. | Жидкие препаративные формы для длительно действующего конъюгата g-csf |
CN102380090A (zh) * | 2010-08-31 | 2012-03-21 | 健能隆医药技术(上海)有限公司 | G-csf二聚体在治疗嗜中性粒细胞减少症中的应用 |
US20160362473A1 (en) * | 2015-06-12 | 2016-12-15 | Ubi Pharma Inc | Immunoglobulin fusion proteins and uses thereof |
EP3773468A2 (en) | 2018-05-04 | 2021-02-17 | Ilkogen Ilaç Sanayi ve Ticaret A.S. | Stable hybrid fc fusion g-csf formulation |
-
2020
- 2020-01-21 ES ES20702699T patent/ES2943312T3/es active Active
- 2020-01-21 KR KR1020217029489A patent/KR20210127215A/ko active Search and Examination
- 2020-01-21 US US16/748,057 patent/US11813310B2/en active Active
- 2020-01-21 CA CA3130032A patent/CA3130032C/en active Active
- 2020-01-21 AU AU2020220651A patent/AU2020220651A1/en active Pending
- 2020-01-21 EP EP20702699.8A patent/EP3923973B1/en active Active
- 2020-01-21 EA EA202192241A patent/EA202192241A1/ru unknown
- 2020-01-21 WO PCT/IB2020/050447 patent/WO2020165664A1/en unknown
- 2020-01-21 DK DK20702699.8T patent/DK3923973T3/da active
- 2020-01-21 BR BR112021015428A patent/BR112021015428A2/pt unknown
Also Published As
Publication number | Publication date |
---|---|
US11813310B2 (en) | 2023-11-14 |
US20200255842A1 (en) | 2020-08-13 |
ES2943312T3 (es) | 2023-06-12 |
CA3130032C (en) | 2024-01-16 |
CA3130032A1 (en) | 2020-08-20 |
EP3923973B1 (en) | 2023-02-01 |
KR20210127215A (ko) | 2021-10-21 |
EP3923973A1 (en) | 2021-12-22 |
EA202192241A1 (ru) | 2022-03-11 |
BR112021015428A2 (pt) | 2022-02-15 |
AU2020220651A1 (en) | 2021-09-09 |
WO2020165664A1 (en) | 2020-08-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3521282T3 (da) | Quinazolinderivater anvendt til behandling af hiv | |
DK3393655T3 (da) | Fenfluramin-sammensætninger og fremgangsmåder til fremstilling af samme | |
DK3307299T3 (da) | Kombinationssammensætninger til behandling af lidelser krævende fjernelse eller ødelæggelse af uønskede celleformeringer | |
DK3524255T3 (da) | Sammensætning til behandling af acne | |
DK3081263T3 (da) | Sammensætninger og redskaber til behandling af glaukom | |
DK3606929T3 (da) | Beta-nicotinat-ester-nukleotider og fremgangsmåder til fremstilling af samme | |
DK3280408T3 (da) | Fremgangsmåde til fremstilling af dicycloplatin | |
DK3261661T3 (da) | Menotropin til behandling af infertilitet | |
DK3459543T3 (da) | Carbamatforbindelse til forebyggelse eller behandling af fibromyalgi | |
GB201808617D0 (en) | Scaffold modification | |
DK3573620T3 (da) | Sammensætninger til behandling af hypertension | |
DK3478713T3 (da) | Sammensætninger til behandling af amyloidose | |
DK3302573T3 (da) | Sammensætning til behandlingen af hjernelæsioner | |
DK3355699T3 (da) | Bicyklisk forbindelse og anvendelse deraf til inhibering af suv39h2 | |
DK3638293T3 (da) | Sammensætninger til behandling af cancer | |
DK3459542T3 (da) | Anvendelse af carbamatforbindelse til forebyggelse eller behandling af trigeminusneuralgi | |
DK3923973T3 (da) | Langtidsvirkende g-csf til forebyggelse af neutropeni eller reduktion af varigheden af neutropeni | |
DK3620452T3 (da) | Fremgangsmåde til fremstilling af lenvatinib | |
DK3709996T3 (da) | Coumarin-derivat til behandling eller forebyggelse af en celleproliferativ lidelse | |
GB201804366D0 (en) | Scaffold | |
DK3490970T3 (da) | Sammensætninger til behandling af lungefibrose | |
DK3236961T3 (da) | Farmaceutisk sammensætning til forebyggelse eller behandling af cancer | |
DK3886799T3 (da) | Sammensætninger til behandlingen af hårtab | |
DK3763212T3 (da) | Artropoda-afvisende sammensætning | |
GB201819609D0 (en) | Scaffold |