DK3909584T3 - Pyrimidinforbindelse eller salt deraf - Google Patents

Pyrimidinforbindelse eller salt deraf Download PDF

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Publication number
DK3909584T3
DK3909584T3 DK20737875.3T DK20737875T DK3909584T3 DK 3909584 T3 DK3909584 T3 DK 3909584T3 DK 20737875 T DK20737875 T DK 20737875T DK 3909584 T3 DK3909584 T3 DK 3909584T3
Authority
DK
Denmark
Prior art keywords
pyrimide
salt
compound
pyrimide compound
Prior art date
Application number
DK20737875.3T
Other languages
English (en)
Other versions
DK3909584T5 (da
Inventor
Masayuki Nakamura
Takahiro Asai
Satoru Iguchi
Kei Oguchi
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of DK3909584T3 publication Critical patent/DK3909584T3/da
Application granted granted Critical
Publication of DK3909584T5 publication Critical patent/DK3909584T5/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK20737875.3T 2019-01-11 2020-01-10 Pyrimidinforbindelse eller salt deraf DK3909584T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019003403 2019-01-11
PCT/JP2020/000592 WO2020145374A1 (ja) 2019-01-11 2020-01-10 ピリミジン化合物又はその塩

Publications (2)

Publication Number Publication Date
DK3909584T3 true DK3909584T3 (da) 2024-01-15
DK3909584T5 DK3909584T5 (da) 2024-08-05

Family

ID=71520288

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20737875.3T DK3909584T5 (da) 2019-01-11 2020-01-10 Pyrimidinforbindelse eller salt deraf

Country Status (19)

Country Link
US (1) US11078207B2 (da)
EP (1) EP3909584B1 (da)
JP (1) JP6783974B1 (da)
KR (1) KR102640463B1 (da)
CN (1) CN113271950B (da)
AU (1) AU2020206640B2 (da)
BR (1) BR112021013460A2 (da)
CA (1) CA3121722C (da)
DK (1) DK3909584T5 (da)
ES (1) ES2969151T3 (da)
FI (1) FI3909584T3 (da)
HU (1) HUE065967T2 (da)
MA (1) MA54702A (da)
MX (1) MX2021008252A (da)
PL (1) PL3909584T3 (da)
PT (1) PT3909584T (da)
SG (1) SG11202107528PA (da)
TW (1) TWI783204B (da)
WO (1) WO2020145374A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3189460A1 (en) 2020-07-15 2022-01-20 Taiho Pharmaceutical Co., Ltd. Egfr inhibitor
MX2023000692A (es) * 2020-07-15 2023-02-13 Taiho Pharmaceutical Co Ltd Cristal de compuesto de pirimidina.
EP4183395A4 (en) * 2020-07-15 2024-07-24 Taiho Pharmaceutical Co Ltd PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT
EP4248974A1 (en) * 2020-11-20 2023-09-27 Taiho Pharmaceutical Co., Ltd. Brain-migrating tumor therapeutic agent containing fused pyrimidine compound as active ingredient
KR20240012522A (ko) * 2021-05-24 2024-01-29 다이호야쿠힌고교 가부시키가이샤 Egfr 및/또는 her2의 이상을 갖는 암이 있는 대상체의 치료 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8426428B2 (en) * 2008-12-05 2013-04-23 Principia Biopharma, Inc. EGFR kinase knockdown via electrophilically enhanced inhibitors
TW201336847A (zh) * 2012-02-07 2013-09-16 Taiho Pharmaceutical Co Ltd 喹啉基吡咯并嘧啶化合物或其鹽
JP6035423B2 (ja) * 2013-08-12 2016-11-30 大鵬薬品工業株式会社 新規な縮合ピリミジン化合物又はその塩
JP6141568B1 (ja) * 2015-09-01 2017-06-07 大鵬薬品工業株式会社 新規なピラゾロ[3,4−d]ピリミジン化合物又はその塩
TWI623316B (zh) * 2015-12-22 2018-05-11 Taiho Pharmaceutical Co Ltd Antitumor effect enhancer derived from pyrrolopyrimidine compound
PT3269370T (pt) 2016-02-23 2020-03-05 Taiho Pharmaceutical Co Ltd Novo composto de pirimidina condensada ou sal do mesmo
CN109952306A (zh) * 2016-04-19 2019-06-28 加利福尼亚大学董事会 ErbB抑制剂及其用途
JP6779835B2 (ja) 2017-06-15 2020-11-04 株式会社日立製作所 監視制御システム、監視制御装置及び監視制御方法

Also Published As

Publication number Publication date
ES2969151T3 (es) 2024-05-16
WO2020145374A1 (ja) 2020-07-16
EP3909584A1 (en) 2021-11-17
KR102640463B1 (ko) 2024-02-23
FI3909584T3 (fi) 2024-01-09
HUE065967T2 (hu) 2024-07-28
CN113271950A (zh) 2021-08-17
TW202043230A (zh) 2020-12-01
PT3909584T (pt) 2024-01-12
CN113271950B (zh) 2024-04-30
MX2021008252A (es) 2021-08-16
CA3121722A1 (en) 2020-07-16
PL3909584T3 (pl) 2024-03-25
BR112021013460A2 (pt) 2021-09-21
MA54702A (fr) 2021-11-17
EP3909584A4 (en) 2022-09-28
CA3121722C (en) 2024-01-16
US20210024530A1 (en) 2021-01-28
US11078207B2 (en) 2021-08-03
DK3909584T5 (da) 2024-08-05
KR20210102373A (ko) 2021-08-19
AU2020206640B2 (en) 2022-09-08
TWI783204B (zh) 2022-11-11
EP3909584B1 (en) 2023-12-13
JP6783974B1 (ja) 2020-11-11
SG11202107528PA (en) 2021-08-30
AU2020206640A1 (en) 2021-08-12
JPWO2020145374A1 (ja) 2021-02-18

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