DK3810157T3 - Supernatant fra samkultur af makrofager og bestrålede leukocytter til anvendelse til kontrol af tumorprogression eller til genoprettelse af antitumorimmunitet - Google Patents
Supernatant fra samkultur af makrofager og bestrålede leukocytter til anvendelse til kontrol af tumorprogression eller til genoprettelse af antitumorimmunitet Download PDFInfo
- Publication number
- DK3810157T3 DK3810157T3 DK19734724.8T DK19734724T DK3810157T3 DK 3810157 T3 DK3810157 T3 DK 3810157T3 DK 19734724 T DK19734724 T DK 19734724T DK 3810157 T3 DK3810157 T3 DK 3810157T3
- Authority
- DK
- Denmark
- Prior art keywords
- macrophages
- restoring
- supernatant
- culture
- tumor progression
- Prior art date
Links
- 206010061309 Neoplasm progression Diseases 0.000 title 1
- 230000005809 anti-tumor immunity Effects 0.000 title 1
- 238000003501 co-culture Methods 0.000 title 1
- 210000000265 leukocyte Anatomy 0.000 title 1
- 210000002540 macrophage Anatomy 0.000 title 1
- 239000006228 supernatant Substances 0.000 title 1
- 230000005751 tumor progression Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4614—Monocytes; Macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1157—Monocytes, macrophages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/30—Coculture with; Conditioned medium produced by tumour cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1800636A FR3082730B1 (fr) | 2018-06-21 | 2018-06-21 | Methode de resolution de l'inflammation pro-tumorale a l'aide d'une preparation pharmaceutique |
| PCT/EP2019/066406 WO2019243544A1 (fr) | 2018-06-21 | 2019-06-20 | Surnageant de coculture entre macrophages et leucocytes irradiés utilisé pour controler une progression tumorale ou pour restaurer une immunite anti-tumorale |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3810157T3 true DK3810157T3 (da) | 2023-02-06 |
Family
ID=63896221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19734724.8T DK3810157T3 (da) | 2018-06-21 | 2019-06-20 | Supernatant fra samkultur af makrofager og bestrålede leukocytter til anvendelse til kontrol af tumorprogression eller til genoprettelse af antitumorimmunitet |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210145874A1 (da) |
| EP (1) | EP3810157B1 (da) |
| JP (1) | JP7483699B2 (da) |
| KR (1) | KR20210022577A (da) |
| CN (1) | CN112334143A (da) |
| CA (1) | CA3101508A1 (da) |
| DK (1) | DK3810157T3 (da) |
| ES (1) | ES2935969T3 (da) |
| FI (1) | FI3810157T3 (da) |
| FR (1) | FR3082730B1 (da) |
| PL (1) | PL3810157T3 (da) |
| WO (1) | WO2019243544A1 (da) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000049096A (ko) * | 1996-10-11 | 2000-07-25 | 린다 에스. 스티븐슨 | 혼합 림프구와 조합된 종양세포를 사용하는 암 면역요법 |
| EP1005531A2 (en) * | 1997-07-21 | 2000-06-07 | Cerus Corporation | Method of treating leukocytes, leukocyte compositions and methods of use thereof |
| AU2616201A (en) * | 1999-10-21 | 2001-04-30 | Center for the Improvement of Human Functioning International, Inc., The | Cancer treatment method |
| US20080089875A1 (en) * | 2006-10-13 | 2008-04-17 | Zheng Cui | Methods and compositions for the treatment of cancer |
| EP2723381A4 (en) * | 2011-06-21 | 2015-03-18 | Univ Johns Hopkins | FOCUSED RADIATION FOR THE REINFORCEMENT OF IMMUNE TREATMENTS AGAINST NEOPLASMS |
| ES2657675T3 (es) * | 2013-01-07 | 2018-03-06 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Terapia de enfermedad mediante el uso de una preparación farmacéutica tolerogénica |
| IL284985B2 (en) | 2015-02-18 | 2023-03-01 | Enlivex Therapeutics R& D Ltd | Combined immunotherapy and cytokine control therapy for cancer treatment |
-
2018
- 2018-06-21 FR FR1800636A patent/FR3082730B1/fr active Active
-
2019
- 2019-06-20 DK DK19734724.8T patent/DK3810157T3/da active
- 2019-06-20 EP EP19734724.8A patent/EP3810157B1/fr active Active
- 2019-06-20 WO PCT/EP2019/066406 patent/WO2019243544A1/fr active Application Filing
- 2019-06-20 KR KR1020207036661A patent/KR20210022577A/ko not_active Application Discontinuation
- 2019-06-20 CN CN201980041571.0A patent/CN112334143A/zh active Pending
- 2019-06-20 FI FIEP19734724.8T patent/FI3810157T3/fi active
- 2019-06-20 JP JP2021520460A patent/JP7483699B2/ja active Active
- 2019-06-20 US US17/252,818 patent/US20210145874A1/en active Pending
- 2019-06-20 ES ES19734724T patent/ES2935969T3/es active Active
- 2019-06-20 CA CA3101508A patent/CA3101508A1/fr active Pending
- 2019-06-20 PL PL19734724.8T patent/PL3810157T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR3082730B1 (fr) | 2022-04-22 |
| JP2021528494A (ja) | 2021-10-21 |
| US20210145874A1 (en) | 2021-05-20 |
| EP3810157A1 (fr) | 2021-04-28 |
| JP7483699B2 (ja) | 2024-05-15 |
| CA3101508A1 (fr) | 2019-12-26 |
| FI3810157T3 (fi) | 2023-02-28 |
| CN112334143A (zh) | 2021-02-05 |
| PL3810157T3 (pl) | 2023-03-13 |
| WO2019243544A1 (fr) | 2019-12-26 |
| FR3082730A1 (fr) | 2019-12-27 |
| KR20210022577A (ko) | 2021-03-03 |
| ES2935969T3 (es) | 2023-03-13 |
| EP3810157B1 (fr) | 2022-11-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB201919389D0 (en) | Methods and systems of assertional simulation | |
| IL266655A (en) | Lymphocytes infiltrating residual tumor and methods for their preparation and use | |
| IL265739A (en) | Surface modeling systems and methods | |
| DK3474996T3 (da) | Tågeapparat og anvendelsesmåde | |
| IL273284A (en) | Preferred promoters in tissue and methods of use | |
| IL262802A (en) | Glucagon receptor selective polypeptides and methods of using them | |
| DK3402888T3 (da) | Middel og fremgangsmåder til behandling af hbv | |
| DK3405037T3 (da) | Fremgangsmåde og system til inddeling af størrelsestilpassede fødevareartikler | |
| DK3102547T3 (da) | Fritter til brug i vakuumisolerende enheder af glas (vig) og/eller associerede fremgangsmåder | |
| IL260717B (en) | Intermediates in the synthesis of eribulin and related methods of synthesis | |
| PT3582839T (pt) | Inalador | |
| PT3582838T (pt) | Inaladores e métodos relacionados | |
| GB201818309D0 (en) | Waterjet systems and methods | |
| DK3220973T3 (da) | Kunstigt lungesystem og fremgangsmåder til anvendelse deraf | |
| GB201819110D0 (en) | Systems and methods of product sortation | |
| DK3177566T3 (da) | Udfældet aluminiumoxid og fremgangsmåde til fremstilling | |
| EP3448876C0 (en) | STREPTAVIDIN MUTUINS AND METHODS OF USE THEREOF | |
| IL267365A (en) | Systems and methods for creating personal genetic profile products | |
| DK3325618T3 (da) | Hidtil ukendte trypsin-isoformer og anvendelse deraf | |
| IL270772B1 (en) | Transplanted cytokine antibody proteins and methods of use for disorders related to the immune system | |
| DK3174559T3 (da) | Radiomærkede antistoffragmenter til anvendelse inden for forebyggelsen og/eller behandlingen af cancer | |
| PT3582837T (pt) | Inaladores | |
| DK3463303T3 (da) | Saposinlipoproteinpartikler og biblioteker fra rå membraner | |
| DK3407949T3 (da) | Systemer til inhalation af terapeutisk og diagnostisk gas og metoder til brug heraf | |
| IL262863A (en) | Dihydrotestosterone and the history and promoters of dihydrotestosterone for cancer treatment |