DK370380A - BETA-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE SAME - Google Patents

BETA-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE SAME

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Publication number
DK370380A
DK370380A DK370380A DK370380A DK370380A DK 370380 A DK370380 A DK 370380A DK 370380 A DK370380 A DK 370380A DK 370380 A DK370380 A DK 370380A DK 370380 A DK370380 A DK 370380A
Authority
DK
Denmark
Prior art keywords
group
hydrogen atom
denote
atom
denotes
Prior art date
Application number
DK370380A
Other languages
Danish (da)
Other versions
DK168292B1 (en
Inventor
U Eder
G Neef
A Huth
D Rahtz
C T Braestrup
M C Nielsen
J A Christensen
M Engelstof
H Schou
R Schmiechen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK88980A external-priority patent/DK88980A/en
Priority claimed from DE19803015816 external-priority patent/DE3015816A1/en
Priority claimed from DE19803023567 external-priority patent/DE3023567A1/en
Application filed by Schering Ag filed Critical Schering Ag
Priority to DK370380A priority Critical patent/DK168292B1/en
Publication of DK370380A publication Critical patent/DK370380A/en
Application granted granted Critical
Publication of DK168292B1 publication Critical patent/DK168292B1/en

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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

β-Carboline-3-carboxylic acid derivatives of the general formula I <IMAGE> where:- X is an oxygen or sulphur atom, NR10, where R10 denotes a hydrogen atom, or a lower alkyl or cycloalkyl group; R3 is an alkoxy, araloxy or aralkoxy group which is optionally substituted by one or more hydroxyl groups; or NR11R12, where R11 and R12 are identical or different and each denote a hydrogen atom, a hydroxyl group, or an alkyl, aryl, aralkyl or cycloalkyl group which is optionally substituted by a hydroxyl, carboxamide, alkoxycarbonyl or monocyclic group or a heterocyclic group; or an amino group which is optionally substituted by an alkyl, aralkyl, aralkyl or cycloalkyl group; or where R11 and R12, together with the adjacent nitrogen atom, form a 5-, 6- or 7-membered heterocyclic ring; with the proviso, however, that R11 and R12 cannot both be a hydroxyl group; or where X and R3 denote a nitrogen atom; R4 is a hydrogen atom, an alkyl group, a cycloalkyl group, an aralkyl group, or a phenyl or alkoxyphenyl group containing up to 10 carbon atoms, RA is H, F, Cl, Br, I, NO2, NR13R14, NHCOR13, CN, COO R13 or OR13, where R13 and R14 are each a hydrogen atom or an alkyl group which contains up to 6 carbon atoms and is optionally substituted by a hydroxyl group or a halogen atom; SCH3 or SO2NR11R12, where R11 and R12 have the abovementioned meaning, and where each molecule can contain two or more identical or different RA groups; R9 is a hydrogen atom, an alkyl group containing up to 8 carbon atoms, or an alkoxycarbonyl group; with the provisos, however:- that R11 and R12 cannot both denote a hydrogen atom when X denotes an oxygen atom and when R4, RA and R9 each denote a hydrogen atom, that one of the substituents R11 and R12 cannot denote a hydrogen atom when the other substituent denotes an amino group and when X denotes an oxygen atom and R4, RA and R9 each denote a hydrogen atom, and that R4, RA and R9 cannot each denote a hydrogen atom when X denotes an oxygen atom and R3 denotes OCH3.
DK370380A 1979-08-29 1980-08-29 Analogy process for preparing beta-carboline-3-carboxylic acid derivatives DK168292B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK370380A DK168292B1 (en) 1979-08-29 1980-08-29 Analogy process for preparing beta-carboline-3-carboxylic acid derivatives

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
DK362279 1979-08-29
DK362279 1979-08-29
DK88980A DK88980A (en) 1980-02-29 1980-02-29 BETA-CARBONLINE-3-CARBOXYLIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THE SAME
DK88980 1980-02-29
DE19803015816 DE3015816A1 (en) 1980-04-22 1980-04-22 Beta-carboline-3-carboxylic acid derivs. - useful as psychotherapeutic agents, esp. tranquillisers and anticonvulsant (PT 10.2.81)
DE3015816 1980-04-22
DE19803023567 DE3023567A1 (en) 1980-06-20 1980-06-20 Beta-carboline-3-carboxylic acid derivs. - useful as psychotherapeutic agents, esp. tranquillisers and anticonvulsant (PT 10.2.81)
DE3023567 1980-06-20
DK370380 1980-08-29
DK370380A DK168292B1 (en) 1979-08-29 1980-08-29 Analogy process for preparing beta-carboline-3-carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
DK370380A true DK370380A (en) 1981-03-01
DK168292B1 DK168292B1 (en) 1994-03-07

Family

ID=27510604

Family Applications (1)

Application Number Title Priority Date Filing Date
DK370380A DK168292B1 (en) 1979-08-29 1980-08-29 Analogy process for preparing beta-carboline-3-carboxylic acid derivatives

Country Status (1)

Country Link
DK (1) DK168292B1 (en)

Also Published As

Publication number Publication date
DK168292B1 (en) 1994-03-07

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed