DK367189D0 - T-pa-derivat og dets fremstilling - Google Patents

T-pa-derivat og dets fremstilling

Info

Publication number
DK367189D0
DK367189D0 DK367189A DK367189A DK367189D0 DK 367189 D0 DK367189 D0 DK 367189D0 DK 367189 A DK367189 A DK 367189A DK 367189 A DK367189 A DK 367189A DK 367189 D0 DK367189 D0 DK 367189D0
Authority
DK
Denmark
Prior art keywords
derivatives
manufacturing
Prior art date
Application number
DK367189A
Other languages
English (en)
Other versions
DK367189A (da
Inventor
Ulrich Weidle
Ralf Mattes
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK367189D0 publication Critical patent/DK367189D0/da
Publication of DK367189A publication Critical patent/DK367189A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK367189A 1988-07-25 1989-07-25 T-pa-derivat og dets fremstilling DK367189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3825253A DE3825253A1 (de) 1988-07-25 1988-07-25 T-pa-derivat und seine herstellung

Publications (2)

Publication Number Publication Date
DK367189D0 true DK367189D0 (da) 1989-07-25
DK367189A DK367189A (da) 1990-01-26

Family

ID=6359511

Family Applications (1)

Application Number Title Priority Date Filing Date
DK367189A DK367189A (da) 1988-07-25 1989-07-25 T-pa-derivat og dets fremstilling

Country Status (4)

Country Link
EP (1) EP0352710A3 (da)
JP (1) JPH02107187A (da)
DE (1) DE3825253A1 (da)
DK (1) DK367189A (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3126381B2 (ja) * 1990-07-31 2001-01-22 ジェネンテク，インコーポレイテッド 減少されたクリアランスを有する組織プラスミノーゲンアクチベーター変異体
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
DE10342518A1 (de) * 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880700856A (ko) * 1985-12-20 1988-04-12 로버어트 에이 아미테이지 조직 플라스미노겐 활성화인자(tpa)상사체
DE3643158A1 (de) * 1986-04-21 1987-11-19 Boehringer Mannheim Gmbh Gewebs-plasminogen-aktivator(tpa) - derivat und seine herstellung

Also Published As

Publication number Publication date
EP0352710A2 (de) 1990-01-31
EP0352710A3 (de) 1990-05-02
JPH02107187A (ja) 1990-04-19
DE3825253A1 (de) 1990-02-01
DK367189A (da) 1990-01-26

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment