DK3500668T3 - Identificering af mål for lægemiddel ved hurtig udvælgelse af lægemiddelresistente mutationer - Google Patents
Identificering af mål for lægemiddel ved hurtig udvælgelse af lægemiddelresistente mutationer Download PDFInfo
- Publication number
- DK3500668T3 DK3500668T3 DK17790663.3T DK17790663T DK3500668T3 DK 3500668 T3 DK3500668 T3 DK 3500668T3 DK 17790663 T DK17790663 T DK 17790663T DK 3500668 T3 DK3500668 T3 DK 3500668T3
- Authority
- DK
- Denmark
- Prior art keywords
- targets
- medicine
- identification
- medicinal products
- quick selection
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1614078.2A GB201614078D0 (en) | 2016-08-17 | 2016-08-17 | Drug-target identification by rapid selection of drug resistance mutations |
| GBGB1711520.5A GB201711520D0 (en) | 2017-07-18 | 2017-07-18 | Drug-target identification by rapid selection of drug resistance mutations |
| PCT/BE2017/000037 WO2018032063A1 (en) | 2016-08-17 | 2017-08-16 | Drug-target identification by rapid selection of drug resistance mutations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3500668T3 true DK3500668T3 (da) | 2020-08-17 |
Family
ID=60182301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17790663.3T DK3500668T3 (da) | 2016-08-17 | 2017-08-16 | Identificering af mål for lægemiddel ved hurtig udvælgelse af lægemiddelresistente mutationer |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20200216837A1 (da) |
| EP (1) | EP3500668B1 (da) |
| CA (1) | CA3034110A1 (da) |
| DK (1) | DK3500668T3 (da) |
| WO (1) | WO2018032063A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110938658B (zh) * | 2018-09-21 | 2023-02-07 | 中国科学院分子细胞科学卓越创新中心 | 一种抗体进化方法及其应用 |
| CN110343700A (zh) * | 2019-07-05 | 2019-10-18 | 中山大学孙逸仙纪念医院 | 一种xpo1基因敲除的胰腺癌细胞系及其构建方法 |
| CN111534577A (zh) * | 2020-05-07 | 2020-08-14 | 西南大学 | 一种高通量筛选真核生物必需基因和生长抑制基因的方法 |
| CN111534578A (zh) * | 2020-05-07 | 2020-08-14 | 西南大学 | 一种高通量筛选真核生物细胞与农药互作的靶点基因的方法 |
| EP4237568A1 (en) * | 2020-10-27 | 2023-09-06 | KWS SAAT SE & Co. KGaA | Use of enhanced pol theta activity for eukaryotic genome engineering |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017223538A1 (en) * | 2016-06-24 | 2017-12-28 | The Regents Of The University Of Colorado, A Body Corporate | Methods for generating barcoded combinatorial libraries |
-
2017
- 2017-08-16 EP EP17790663.3A patent/EP3500668B1/en active Active
- 2017-08-16 US US16/325,949 patent/US20200216837A1/en active Pending
- 2017-08-16 WO PCT/BE2017/000037 patent/WO2018032063A1/en active Search and Examination
- 2017-08-16 CA CA3034110A patent/CA3034110A1/en active Pending
- 2017-08-16 DK DK17790663.3T patent/DK3500668T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3034110A1 (en) | 2018-02-22 |
| EP3500668A1 (en) | 2019-06-26 |
| US20200216837A1 (en) | 2020-07-09 |
| WO2018032063A1 (en) | 2018-02-22 |
| EP3500668B1 (en) | 2020-06-17 |
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