DK3463303T3 - Saposinlipoproteinpartikler og biblioteker fra rå membraner - Google Patents

Saposinlipoproteinpartikler og biblioteker fra rå membraner Download PDF

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Publication number
DK3463303T3
DK3463303T3 DK17755497.9T DK17755497T DK3463303T3 DK 3463303 T3 DK3463303 T3 DK 3463303T3 DK 17755497 T DK17755497 T DK 17755497T DK 3463303 T3 DK3463303 T3 DK 3463303T3
Authority
DK
Denmark
Prior art keywords
libraries
lipoprotein particles
saposin lipoprotein
membranes
raw
Prior art date
Application number
DK17755497.9T
Other languages
Danish (da)
English (en)
Inventor
Jens Frauenfeld
Robin Löving
Original Assignee
Salipro Biotech AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salipro Biotech AB filed Critical Salipro Biotech AB
Application granted granted Critical
Publication of DK3463303T3 publication Critical patent/DK3463303T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0012—Lipids; Lipoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
DK17755497.9T 2016-08-19 2017-08-21 Saposinlipoproteinpartikler og biblioteker fra rå membraner DK3463303T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16184843.7A EP3284460A1 (en) 2016-08-19 2016-08-19 Saposin lipoprotein particles and libraries from crude membranes
PCT/EP2017/071043 WO2018033647A1 (en) 2016-08-19 2017-08-21 Saposin lipoprotein particles and libraries from crude membranes

Publications (1)

Publication Number Publication Date
DK3463303T3 true DK3463303T3 (da) 2020-06-15

Family

ID=56740926

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17755497.9T DK3463303T3 (da) 2016-08-19 2017-08-21 Saposinlipoproteinpartikler og biblioteker fra rå membraner

Country Status (9)

Country Link
US (1) US11346843B2 (enExample)
EP (2) EP3284460A1 (enExample)
JP (3) JP7149929B2 (enExample)
CN (1) CN109640960B (enExample)
CA (1) CA3034136A1 (enExample)
DK (1) DK3463303T3 (enExample)
ES (1) ES2797257T3 (enExample)
PT (1) PT3463303T (enExample)
WO (1) WO2018033647A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3725304A1 (en) * 2019-04-15 2020-10-21 Salipro Biotech AB Production of salipro particles
CN110483618B (zh) * 2019-09-11 2022-09-09 青岛科技大学 杂[4]芳烃衍生物及其制备和应用
CN111040019B (zh) * 2019-12-25 2022-06-07 上海交通大学 一种用于与TfR蛋白特异性结合的配体多肽及其应用
CA3197426A1 (en) 2020-12-23 2022-06-30 Regeneron Pharmaceuticals, Inc. Methods for obtaining antibodies that bind transmembrane proteins and cells that produce the same
US20220268785A1 (en) * 2021-02-19 2022-08-25 Northwestern University Facile sample preparation for quantitative single-cell proteomics
JP7808617B2 (ja) * 2021-03-31 2026-01-29 ユニヴェルシテ・グルノーブル・アルプ ナノ構造生体模倣ニューロモルフィックシステム
EP4123307A1 (en) 2021-07-22 2023-01-25 Salipro Biotech AB Methods for structure determination and drug design using salipro particles
WO2023001912A1 (en) 2021-07-22 2023-01-26 Salipro Biotech AB Methods for structure determination and drug design using salipro particles

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872406B2 (en) * 2000-02-11 2005-03-29 Children's Hospital Research Foundation Fusogenic properties of saposin C and related proteins and polypeptides for application to transmembrane drug delivery systems
CN1474831A (zh) 2000-11-20 2004-02-11 ����ŵ˹������ѧ�йܻ� 膜支架蛋白
WO2004073684A2 (en) 2003-02-14 2004-09-02 Children's Hospital & Research Center At Oakland Lipophilic drug delivery vehicle and methods of use thereof
CN103585105A (zh) * 2008-11-07 2014-02-19 儿童医院医疗中心 用于跨膜药物递送系统的鞘脂激活蛋白c以及相关蛋白和肽促融合性质
GB0913823D0 (en) 2009-08-07 2009-09-16 Isis Innovation Bilayers
ES2608857T3 (es) * 2012-12-18 2017-04-17 Salipro Biotech Ag Partículas Salipro
LT3043814T (lt) 2013-09-13 2021-02-25 Salipro Biotech AB Antigenas ir jo gamybos būdas

Also Published As

Publication number Publication date
JP7702167B2 (ja) 2025-07-03
US20190204337A1 (en) 2019-07-04
CA3034136A1 (en) 2018-02-22
US11346843B2 (en) 2022-05-31
EP3463303B1 (en) 2020-03-11
WO2018033647A1 (en) 2018-02-22
EP3463303A1 (en) 2019-04-10
JP7149929B2 (ja) 2022-10-07
ES2797257T3 (es) 2020-12-01
PT3463303T (pt) 2020-06-18
JP7460700B2 (ja) 2024-04-02
JP2024096708A (ja) 2024-07-17
CN109640960A (zh) 2019-04-16
CN109640960B (zh) 2022-08-12
EP3284460A1 (en) 2018-02-21
JP2019529360A (ja) 2019-10-17
JP2022163077A (ja) 2022-10-25

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