DK3433618T3 - Osteomodulin og osteomoduline fragmenter som biomarkører for slidgigt og anvendelse deraf - Google Patents

Osteomodulin og osteomoduline fragmenter som biomarkører for slidgigt og anvendelse deraf Download PDF

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Publication number
DK3433618T3
DK3433618T3 DK16822621.5T DK16822621T DK3433618T3 DK 3433618 T3 DK3433618 T3 DK 3433618T3 DK 16822621 T DK16822621 T DK 16822621T DK 3433618 T3 DK3433618 T3 DK 3433618T3
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DK
Denmark
Prior art keywords
osteomodulin
biomarkers
osteoarthritis
fragments
osteomodulin fragments
Prior art date
Application number
DK16822621.5T
Other languages
English (en)
Inventor
Yves Henrotin
Christelle Sanchez
Pauw Edwin De
Gabriel Mazzucchelli
Original Assignee
Univ Liege
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Liege filed Critical Univ Liege
Application granted granted Critical
Publication of DK3433618T3 publication Critical patent/DK3433618T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/105Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK16822621.5T 2016-03-25 2016-12-08 Osteomodulin og osteomoduline fragmenter som biomarkører for slidgigt og anvendelse deraf DK3433618T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16162499.4A EP3223017A1 (en) 2016-03-25 2016-03-25 Osteomodulin and osteomodulin fragments as biomarkers for osteoarthritis and use thereof
PCT/EP2016/080348 WO2017162322A1 (en) 2016-03-25 2016-12-08 Osteomodulin and osteomodulin fragments as biomarkers for osteoarthritis and use thereof

Publications (1)

Publication Number Publication Date
DK3433618T3 true DK3433618T3 (da) 2020-11-16

Family

ID=55808937

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16822621.5T DK3433618T3 (da) 2016-03-25 2016-12-08 Osteomodulin og osteomoduline fragmenter som biomarkører for slidgigt og anvendelse deraf

Country Status (7)

Country Link
US (2) US11255862B2 (da)
EP (2) EP3223017A1 (da)
JP (1) JP6817315B2 (da)
DK (1) DK3433618T3 (da)
ES (1) ES2823280T3 (da)
PT (1) PT3433618T (da)
WO (1) WO2017162322A1 (da)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030004311A1 (en) * 1997-06-18 2003-01-02 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20110189694A1 (en) * 2008-10-22 2011-08-04 Biomarker Design Forschungs Gmbh Methods for detection and diagnosis of a bone or cartilage disorder

Also Published As

Publication number Publication date
EP3433618A1 (en) 2019-01-30
JP2019513223A (ja) 2019-05-23
US20220196680A1 (en) 2022-06-23
EP3223017A1 (en) 2017-09-27
US20190011459A1 (en) 2019-01-10
JP6817315B2 (ja) 2021-01-20
ES2823280T3 (es) 2021-05-06
WO2017162322A1 (en) 2017-09-28
US11255862B2 (en) 2022-02-22
PT3433618T (pt) 2020-11-13
EP3433618B1 (en) 2020-09-09

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