DK341181A - Fremgangsmaade til fremstilling af benzodiazepin-derivater eller farmaceutisk acceptable syreadditionssalte deraf samt ved fremgangsmaaden som mellemprodukter anvendelige forbindelser - Google Patents
Fremgangsmaade til fremstilling af benzodiazepin-derivater eller farmaceutisk acceptable syreadditionssalte deraf samt ved fremgangsmaaden som mellemprodukter anvendelige forbindelserInfo
- Publication number
- DK341181A DK341181A DK341181A DK341181A DK341181A DK 341181 A DK341181 A DK 341181A DK 341181 A DK341181 A DK 341181A DK 341181 A DK341181 A DK 341181A DK 341181 A DK341181 A DK 341181A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- intermediates
- preparation
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH584180 | 1980-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK341181A true DK341181A (da) | 1982-02-01 |
Family
ID=4300189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK341181A DK341181A (da) | 1980-07-31 | 1981-07-30 | Fremgangsmaade til fremstilling af benzodiazepin-derivater eller farmaceutisk acceptable syreadditionssalte deraf samt ved fremgangsmaaden som mellemprodukter anvendelige forbindelser |
Country Status (9)
Country | Link |
---|---|
US (1) | US4327026A (da) |
EP (1) | EP0045452A3 (da) |
JP (1) | JPS5758674A (da) |
AU (1) | AU7339781A (da) |
CA (1) | CA1157855A (da) |
DK (1) | DK341181A (da) |
IL (1) | IL63406A0 (da) |
PH (1) | PH17045A (da) |
ZA (1) | ZA815115B (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3431195A1 (de) * | 1984-08-24 | 1986-03-06 | Troponwerke GmbH & Co KG, 5000 Köln | Neue benzodiazepine, verfahren zu ihrer herstellung sowie ihre verwendung |
US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
ES2190428T3 (es) * | 1991-06-28 | 2003-08-01 | Smithkline Beecham Corp | Antagonistas biciclicos de fibrinogeno. |
US6403578B1 (en) | 1993-12-21 | 2002-06-11 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
US6100254A (en) * | 1997-10-10 | 2000-08-08 | Board Of Regents, The University Of Texas System | Inhibitors of protein tyrosine kinases |
AR084070A1 (es) | 2010-12-02 | 2013-04-17 | Constellation Pharmaceuticals Inc | Inhibidores del bromodominio y usos de los mismos |
WO2012075456A1 (en) | 2010-12-02 | 2012-06-07 | Constellation Pharmaceuticals | Bromodomain inhibitors and uses thereof |
EP2705039B1 (en) | 2011-05-04 | 2017-07-26 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
EP2721031B1 (en) | 2011-06-17 | 2016-01-20 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
WO2013184878A1 (en) | 2012-06-06 | 2013-12-12 | Constellation Pharmaceuticals, Inc. | Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof |
TWI602820B (zh) | 2012-06-06 | 2017-10-21 | 星宿藥物公司 | 溴域抑制劑及其用途 |
ES2725928T3 (es) | 2014-06-20 | 2019-09-30 | Constellation Pharmaceuticals Inc | Formas cristalinas de 2-((4S)-6-(4-clorofenil)-1-metil-4H-benzo[c]isoxazolo[4,5-e]azepin-4-il)acetamida |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL23270A (en) * | 1964-04-10 | 1969-02-27 | Hoffmann La Roche | Quinazoline derivatives and process for the manufacture and conversion thereof |
DE2163622A1 (de) * | 1971-12-21 | 1973-06-28 | Standard Elektrik Lorenz Ag | Steuerung von wechselspannungsgeraeten |
CA1114373A (en) * | 1978-08-11 | 1981-12-15 | Albert E. Fischli | Benzodiazepine derivatives |
-
1981
- 1981-06-25 CA CA000380555A patent/CA1157855A/en not_active Expired
- 1981-07-16 US US06/283,711 patent/US4327026A/en not_active Expired - Fee Related
- 1981-07-23 EP EP81105835A patent/EP0045452A3/de not_active Ceased
- 1981-07-24 PH PH25962A patent/PH17045A/en unknown
- 1981-07-24 IL IL63406A patent/IL63406A0/xx unknown
- 1981-07-24 AU AU73397/81A patent/AU7339781A/en not_active Abandoned
- 1981-07-24 ZA ZA815115A patent/ZA815115B/xx unknown
- 1981-07-30 DK DK341181A patent/DK341181A/da not_active Application Discontinuation
- 1981-07-30 JP JP56118570A patent/JPS5758674A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA1157855A (en) | 1983-11-29 |
US4327026A (en) | 1982-04-27 |
JPS5758674A (en) | 1982-04-08 |
ZA815115B (en) | 1982-08-25 |
PH17045A (en) | 1984-05-17 |
EP0045452A2 (de) | 1982-02-10 |
IL63406A0 (en) | 1981-10-30 |
EP0045452A3 (de) | 1982-03-31 |
AU7339781A (en) | 1982-02-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |