DK3384045T3 - Fremgangsmåde til bestemmelse af celleklonalitet - Google Patents

Fremgangsmåde til bestemmelse af celleklonalitet Download PDF

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Publication number
DK3384045T3
DK3384045T3 DK16809319.3T DK16809319T DK3384045T3 DK 3384045 T3 DK3384045 T3 DK 3384045T3 DK 16809319 T DK16809319 T DK 16809319T DK 3384045 T3 DK3384045 T3 DK 3384045T3
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DK
Denmark
Prior art keywords
determining cell
cell clonality
clonality
determining
cell
Prior art date
Application number
DK16809319.3T
Other languages
English (en)
Inventor
Neve Fabio La
Georg Feger
Emiliano Toso
Original Assignee
Ares Trading Sa
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Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK3384045T3 publication Critical patent/DK3384045T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/10Design of libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Library & Information Science (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK16809319.3T 2015-12-03 2016-12-01 Fremgangsmåde til bestemmelse af celleklonalitet DK3384045T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15197894 2015-12-03
PCT/EP2016/079427 WO2017093400A1 (en) 2015-12-03 2016-12-01 Method for determining cell clonality

Publications (1)

Publication Number Publication Date
DK3384045T3 true DK3384045T3 (da) 2021-04-06

Family

ID=54843664

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16809319.3T DK3384045T3 (da) 2015-12-03 2016-12-01 Fremgangsmåde til bestemmelse af celleklonalitet

Country Status (14)

Country Link
US (2) US20180327830A1 (da)
EP (1) EP3384045B1 (da)
JP (1) JP6904953B2 (da)
KR (1) KR20180088867A (da)
CN (1) CN108368549B (da)
AU (3) AU2016363746A1 (da)
CA (1) CA3005386A1 (da)
DK (1) DK3384045T3 (da)
ES (1) ES2861477T3 (da)
HK (1) HK1253370A1 (da)
HU (1) HUE054222T2 (da)
IL (1) IL259750B (da)
PL (1) PL3384045T3 (da)
WO (1) WO2017093400A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020011759A1 (en) * 2018-07-09 2020-01-16 Ichnos Sciences S.A. Methods to determine the monoclonality of a cell population
EP3822366A1 (en) * 2019-11-13 2021-05-19 Ichnos Sciences SA Methods to determine the monoclonality of a cell population
CN111733262A (zh) * 2020-08-17 2020-10-02 江苏集萃药康生物科技有限公司 一种用于检测外源基因整合状况的核酸组合物及其方法
GB202104715D0 (en) * 2021-04-01 2021-05-19 Achilles Therapeutics Uk Ltd Identification of clonal neoantigens and uses thereof
CN113223619B (zh) * 2021-06-17 2024-07-09 南京诺因生物科技有限公司 比对不同全基因组测序方法的测序结果覆盖率的方法
EP4239638A1 (en) * 2022-03-03 2023-09-06 Ares Trading S.A. Method for determining viral contamination
CA3223241A1 (en) * 2021-07-02 2023-01-05 Simone OLGIATI Method for determining viral contamination

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0149547A2 (en) * 1984-01-18 1985-07-24 The Board Of Trustees Of The Leland Stanford Junior University Neoplastic diagnosis by detection of gene rearrangements
CN101023101A (zh) * 2004-07-20 2007-08-22 西福根有限公司 抗-恒河猴d重组多克隆抗体和生产方法
US20130130311A1 (en) * 2010-07-27 2013-05-23 Yeda Research And Development Co., Ltd. Methods and systems for assessing clonality of cell cultures
WO2012083069A2 (en) * 2010-12-15 2012-06-21 The Board Of Trustees Of The Leland Stanford Junior University Measurement and monitoring of cell clonality
CN103620405B (zh) * 2010-12-31 2016-05-25 生物蛋白有限公司 全面单克隆抗体产生
IL217216A0 (en) * 2011-12-27 2012-07-31 Merck Serono Sa Low fucose cell lins and uses thereof
WO2014058987A1 (en) * 2012-10-09 2014-04-17 Five3 Genomics, Llc Systems and methods for tumor clonality analysis
WO2015017496A1 (en) * 2013-08-01 2015-02-05 Abbvie Inc. Methods of selecting biologic-producing cell lines by next generation sequencing

Also Published As

Publication number Publication date
JP6904953B2 (ja) 2021-07-21
AU2023204140A1 (en) 2023-07-20
HK1253370A1 (zh) 2019-06-14
IL259750A (en) 2018-08-30
US20180327830A1 (en) 2018-11-15
HUE054222T2 (hu) 2021-08-30
JP2018537097A (ja) 2018-12-20
AU2026200380A1 (en) 2026-02-05
IL259750B (en) 2021-03-25
CA3005386A1 (en) 2017-06-08
US20230151421A1 (en) 2023-05-18
KR20180088867A (ko) 2018-08-07
PL3384045T3 (pl) 2021-07-12
CN108368549A (zh) 2018-08-03
ES2861477T3 (es) 2021-10-06
WO2017093400A1 (en) 2017-06-08
EP3384045B1 (en) 2021-01-20
AU2016363746A1 (en) 2018-05-31
EP3384045A1 (en) 2018-10-10
CN108368549B (zh) 2022-02-22

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