DK337489A - Spiro-azabicyclisk forbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse samt fremgangsmaade til fremstilling af en saadan forbindelse - Google Patents
Spiro-azabicyclisk forbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse samt fremgangsmaade til fremstilling af en saadan forbindelse Download PDFInfo
- Publication number
- DK337489A DK337489A DK337489A DK337489A DK337489A DK 337489 A DK337489 A DK 337489A DK 337489 A DK337489 A DK 337489A DK 337489 A DK337489 A DK 337489A DK 337489 A DK337489 A DK 337489A
- Authority
- DK
- Denmark
- Prior art keywords
- relationship
- azabicyclic
- spiro
- procedure
- making
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D497/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888816299A GB8816299D0 (en) | 1988-07-08 | 1988-07-08 | Therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK337489D0 DK337489D0 (da) | 1989-07-07 |
| DK337489A true DK337489A (da) | 1990-01-09 |
Family
ID=10640121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK337489A DK337489A (da) | 1988-07-08 | 1989-07-07 | Spiro-azabicyclisk forbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse samt fremgangsmaade til fremstilling af en saadan forbindelse |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4992436A (da) |
| EP (1) | EP0350118A3 (da) |
| JP (1) | JPH0272179A (da) |
| DK (1) | DK337489A (da) |
| GB (1) | GB8816299D0 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0445974A3 (en) * | 1990-03-05 | 1992-04-29 | Merck Sharp & Dohme Ltd. | Spirocyclic antipsychotic agents |
| IL97726A (en) * | 1990-04-10 | 1994-12-29 | Israel Inst Biolog Res | Pharmaceutical preparations containing compounds with bridged and unbridged heterocyclic groups connected via spiro-atop with oxazoline and thiazoline groups, and sharp compounds |
| US5407938A (en) * | 1990-04-10 | 1995-04-18 | Israel Institute For Biological Research | Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines) |
| US5817679A (en) * | 1993-04-01 | 1998-10-06 | University Of Virginia | 7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands |
| US6060473A (en) * | 1993-04-01 | 2000-05-09 | Ucb S.A. - Dtb | 7-azabicyclo[2.2.1]-heptane and -heptene derivatives as cholinergic receptor ligands |
| JPH11501282A (ja) * | 1993-09-10 | 1999-02-02 | サイトメッド、インコーポレイテッド | コリン受容体作用薬及び拮抗薬としてのエピバチジン及びその誘導体 |
| US6117889A (en) * | 1994-04-01 | 2000-09-12 | University Of Virginia | 7-Azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents |
| DK0777671T3 (da) * | 1994-08-24 | 2000-07-24 | Astrazeneca Ab | Spiro-azabicykliske forbindelser |
| CA2289578A1 (en) * | 1997-05-30 | 1998-12-03 | Neurosearch A/S | Spiro-quinuclidine derivatives, their preparation and use |
| US8673931B2 (en) * | 2009-01-26 | 2014-03-18 | Abraham Fisher | Bicyclic heterocyclic spiro compounds |
| US9034891B2 (en) | 2009-01-26 | 2015-05-19 | Israel Institute For Biological Research | Bicyclic heterocyclic spiro compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL48452A (en) * | 1975-11-11 | 1979-07-25 | Purdue Frederick Co | Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them |
| EP0189370A3 (de) * | 1985-01-16 | 1988-01-27 | Sandoz Ag | Spiro-dioxolane, -dithiolane und -oxothiolane |
| US4855290A (en) * | 1985-05-10 | 1989-08-08 | State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research | Derivatives of quinuclidine |
| NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
| EP0261763B1 (en) * | 1986-06-27 | 1994-02-09 | Beecham Group Plc | Novel bridged bicyclic N-heterocycles |
-
1988
- 1988-07-08 GB GB888816299A patent/GB8816299D0/en active Pending
-
1989
- 1989-06-29 US US07/373,001 patent/US4992436A/en not_active Expired - Fee Related
- 1989-06-30 EP EP89201750A patent/EP0350118A3/en not_active Ceased
- 1989-07-07 DK DK337489A patent/DK337489A/da not_active Application Discontinuation
- 1989-07-07 JP JP1174365A patent/JPH0272179A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0272179A (ja) | 1990-03-12 |
| GB8816299D0 (en) | 1988-08-10 |
| DK337489D0 (da) | 1989-07-07 |
| EP0350118A3 (en) | 1990-05-30 |
| EP0350118A2 (en) | 1990-01-10 |
| US4992436A (en) | 1991-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |