DK287085D0 - Triazolobenzodiazepin og farmaceutisk praeparat indeholdende en saadanforbindelse - Google Patents

Triazolobenzodiazepin og farmaceutisk praeparat indeholdende en saadanforbindelse

Info

Publication number
DK287085D0
DK287085D0 DK287085A DK287085A DK287085D0 DK 287085 D0 DK287085 D0 DK 287085D0 DK 287085 A DK287085 A DK 287085A DK 287085 A DK287085 A DK 287085A DK 287085 D0 DK287085 D0 DK 287085D0
Authority
DK
Denmark
Prior art keywords
triazolobenzodiazepine
pharmaceutical preparation
preparation containing
seed connection
seed
Prior art date
Application number
DK287085A
Other languages
English (en)
Other versions
DK287085A (da
Inventor
Ben E Evans
Roger M Freidinger
Mark G Bock
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK287085D0 publication Critical patent/DK287085D0/da
Publication of DK287085A publication Critical patent/DK287085A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/22Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK287085A 1984-06-26 1985-06-25 Triazolobenzodiazepin og farmaceutisk praeparat indeholdende en saadanforbindelse DK287085A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62485084A 1984-06-26 1984-06-26
US06/741,971 US4663321A (en) 1984-06-26 1985-06-10 Triazolobenzodiazepines and pharmaceutical use

Publications (2)

Publication Number Publication Date
DK287085D0 true DK287085D0 (da) 1985-06-25
DK287085A DK287085A (da) 1986-03-05

Family

ID=27089769

Family Applications (1)

Application Number Title Priority Date Filing Date
DK287085A DK287085A (da) 1984-06-26 1985-06-25 Triazolobenzodiazepin og farmaceutisk praeparat indeholdende en saadanforbindelse

Country Status (4)

Country Link
US (1) US4663321A (da)
EP (1) EP0169392A3 (da)
DK (1) DK287085A (da)
ES (2) ES8704946A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU136287A (en) * 1986-07-25 1990-06-30 Boehringer Kg Process for preparing new 1,4 benzodiazepines
EP0272866A1 (en) * 1986-12-23 1988-06-29 Merck & Co. Inc. 1,4-Benzodiazepines with 5-membered heterocyclic rings
US4735941A (en) * 1986-12-23 1988-04-05 Merck & Co., Inc. 1,4-benzodiazepines with 5- and 6-membered heterocyclic rings, useful as gastrointestinal and CNS agents
EP0272868A1 (en) * 1986-12-23 1988-06-29 Merck & Co. Inc. 1,4-Benzodiazepines with 6-membered heterocyclic rings
EP0273697A3 (en) * 1986-12-30 1989-11-29 Merck & Co. Inc. 2-benzazepines with 5- and 6- membered heterocyclic rings
US5185331A (en) * 1991-05-14 1993-02-09 Merck & Co., Inc. Triazolobenzodiazepines
EP0523846A3 (en) * 1991-06-14 1993-03-17 Merck & Co. Inc. 1,4-benzodiazepines with 5-membered heterocyclic rings
US5679672A (en) * 1993-11-22 1997-10-21 Merck & Co., Inc. Benzodiazepines
WO1998000406A1 (en) * 1996-07-02 1998-01-08 Merck & Co., Inc. Method for the treatment of preterm labor
US5929071A (en) * 1996-07-02 1999-07-27 Merck & Co., Inc. Method for the treatment of preterm labor
US7119088B2 (en) * 2003-02-19 2006-10-10 Pfizer Inc. Triazole compounds useful in therapy
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
WO2012075456A1 (en) 2010-12-02 2012-06-07 Constellation Pharmaceuticals Bromodomain inhibitors and uses thereof
EP2705039B1 (en) 2011-05-04 2017-07-26 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2721031B1 (en) 2011-06-17 2016-01-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
WO2013184878A1 (en) 2012-06-06 2013-12-12 Constellation Pharmaceuticals, Inc. Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof
US9969747B2 (en) 2014-06-20 2018-05-15 Constellation Pharmaceuticals, Inc. Crystalline forms of 2-((4S)-6-(4-chlorophenyl)-1-methyl-4H-benzo[C]isoxazolo[4,5-e]azepin-4-yl)acetamide
US20160243139A1 (en) * 2014-10-29 2016-08-25 Glycom A/S Composition comprising HMSs/HMOs and use thereof
US11040049B2 (en) 2014-10-29 2021-06-22 Glycom A/S Composition comprising HMSs/HMOs and use thereof
EP3212197A4 (en) 2014-10-29 2018-07-11 Glycom A/S Synthetic composition and method for treating irritable bowel syndrome
US11040050B2 (en) 2014-10-29 2021-06-22 Glycom A/S Composition comprising HMSs/HMOs and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880877A (en) * 1972-11-03 1975-04-29 American Home Prod Process for the preparation of 6-aryl-4H-s-triazolo(4,3-a)(1,4)benzodiazepines
JPS5747914B2 (da) * 1974-04-12 1982-10-13
US3910944A (en) * 1974-11-20 1975-10-07 Upjohn Co Spiro(cyclopropane-1,4{40 -(4H)-s-triazolo-(4,3-a)(1,4)benzodiazepines)
US4180668A (en) * 1977-06-08 1979-12-25 The Upjohn Company Piperidino-4H-s-triazolo[4,3-a][1,4]benzodiazepines

Also Published As

Publication number Publication date
ES557126A0 (es) 1987-08-16
EP0169392A3 (en) 1986-11-05
EP0169392A2 (en) 1986-01-29
ES544521A0 (es) 1987-04-16
ES8704946A1 (es) 1987-04-16
US4663321A (en) 1987-05-05
DK287085A (da) 1986-03-05
ES8707733A1 (es) 1987-08-16

Similar Documents

Publication Publication Date Title
DK284485D0 (da) Indol-2-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse
DK287085A (da) Triazolobenzodiazepin og farmaceutisk praeparat indeholdende en saadanforbindelse
DK314789A (da) Quinolinetheralkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse
DK85985D0 (da) Carbamoyl- eller acyl-4-aza-5alfa-androst-1-en-3-on og farmaceutisk praeparat indeholdende en saadan forbindelse
DK404588A (da) Tetrahydrocabazol-1-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse
DK481585A (da) Farmaceutisk praeparat indeholdende anthracyclinglycosider
DK181586D0 (da) 2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdende en saadanforbindelse og fremgangsmaade til fremstilling af en saadan forbindelse
DK655288D0 (da) Diarylstyrylquinolindisyre og farmaceutisk praeparat indeholdende en saadan forbindelse
DK497685A (da) Ketongruppeholdige oxindol-3-carboxamid-derivater og laegemiddel indeholdende saadanne derivater
DK224589D0 (da) Polymalonsyreforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK537288D0 (da) Tetrahydrocarbazolester og farmaceutisk praeparat indeholdende en saadan forbindelse
DK375584D0 (da) Piperidinoquinazolinforbindelser og farmaceutisk praeparat indeholdene en saadan forbindelse
DK48790A (da) Steroidforbindelse og farmaceutisk praeparat indeholden en saadan forbindelse
DK316287A (da) Leukotrienantagonist og farmaceutisk praeparat indeholdende en saadan
DK191787D0 (da) Carbapenemforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK23088D0 (da) Piperazinylpyrimidinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK287185D0 (da) Benzodiazepinderivat og farmaceutisk praeparat indeholdende et saadantderivat
DK258086A (da) Substitueret hexahydroarylquinolin og farmaceutisk praeparat indeholdende en saadan forbindelse
DK318385D0 (da) Farmaceutiske og kosmetiske praeparater indeholdende et phenylanthronderivat
DK52484A (da) Mitomycin-analoger og farmaceutisk praeparat indeholdende en saadan forbindelse
DK151785A (da) 3-aminoalkylthio-1-phenylindolforbindelser og farmaceutiske praeparater
DK36385D0 (da) Goedningsoploesninger og disses fremstilling
DK153842C (da) Dihydrodibenzotiepinderivat og farmaceutisk praeparat indeholdende det
DK330389D0 (da) Tetrahydropyranonforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK553285D0 (da) Fenoxypropanolaminsalte og farmaceutiske praeparater deraf

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment