DK3370727T3 - Non-biokonvertible C3-substituerede pregnenolon-derivater til anvendelse ved behandling af stofmisbrugslidelser - Google Patents

Non-biokonvertible C3-substituerede pregnenolon-derivater til anvendelse ved behandling af stofmisbrugslidelser Download PDF

Info

Publication number
DK3370727T3
DK3370727T3 DK16791589.1T DK16791589T DK3370727T3 DK 3370727 T3 DK3370727 T3 DK 3370727T3 DK 16791589 T DK16791589 T DK 16791589T DK 3370727 T3 DK3370727 T3 DK 3370727T3
Authority
DK
Denmark
Prior art keywords
bioconvertible
treatment
substance abuse
abuse disorders
pregnenolone derivatives
Prior art date
Application number
DK16791589.1T
Other languages
English (en)
Inventor
George F Koob
Mason Barbara Jean
Olivier George
Etienne Baulieu
Isabelle Villey
Original Assignee
Mapreg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mapreg filed Critical Mapreg
Application granted granted Critical
Publication of DK3370727T3 publication Critical patent/DK3370727T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Addiction (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK16791589.1T 2015-11-06 2016-11-04 Non-biokonvertible C3-substituerede pregnenolon-derivater til anvendelse ved behandling af stofmisbrugslidelser DK3370727T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15306765.7A EP3165225A1 (en) 2015-11-06 2015-11-06 Non-bioconvertible c3-substituted pregnenolone derivatives for use in the treatment of substance use disorders
PCT/EP2016/076741 WO2017077082A1 (en) 2015-11-06 2016-11-04 Non-bioconvertible c3-substituted pregnenolone derivatives for use in the treatment of substance use disorders

Publications (1)

Publication Number Publication Date
DK3370727T3 true DK3370727T3 (da) 2022-04-11

Family

ID=54539995

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16791589.1T DK3370727T3 (da) 2015-11-06 2016-11-04 Non-biokonvertible C3-substituerede pregnenolon-derivater til anvendelse ved behandling af stofmisbrugslidelser

Country Status (10)

Country Link
US (2) US11077122B2 (da)
EP (2) EP3165225A1 (da)
AU (1) AU2016349439B2 (da)
CA (1) CA3004366C (da)
DK (1) DK3370727T3 (da)
ES (1) ES2911348T3 (da)
HU (1) HUE058845T2 (da)
PL (1) PL3370727T3 (da)
PT (1) PT3370727T (da)
WO (1) WO2017077082A1 (da)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2850023B1 (fr) 2003-01-17 2007-04-06 Mapreg Medicaments pour le systeme nerveux
US9339508B2 (en) 2003-01-17 2016-05-17 Mapreg Use of 3-methoxy-pregnenolone for the preparation of a drug for treating a traumatic brain injury
SI2709631T1 (sl) 2011-05-20 2017-07-31 INSERM -Institut National de la Sante et de la Recherche Medicale Antagonisti receptorja cb1

Also Published As

Publication number Publication date
EP3165225A1 (en) 2017-05-10
EP3370727A1 (en) 2018-09-12
CA3004366A1 (en) 2017-05-11
PT3370727T (pt) 2022-04-18
EP3370727B1 (en) 2022-01-19
US20180318317A1 (en) 2018-11-08
US11077122B2 (en) 2021-08-03
PL3370727T3 (pl) 2022-05-16
WO2017077082A1 (en) 2017-05-11
ES2911348T3 (es) 2022-05-18
HUE058845T2 (hu) 2022-09-28
CA3004366C (en) 2023-10-31
AU2016349439B2 (en) 2022-06-09
AU2016349439A8 (en) 2018-06-28
US20210322443A1 (en) 2021-10-21
AU2016349439A1 (en) 2018-05-24

Similar Documents

Publication Publication Date Title
DK3307262T3 (da) Forbindelser til anvendelse ved behandling af neuromuskulære lidelser
DK3119397T3 (da) Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser
DK3185957T3 (da) Patisiran til anvendelse ved behandlingen af transthyretin-medieret amyloidosis
DK3882250T3 (da) Tetrahydropyranyl-amino-pyrrolopyrimidinon til anvendelse i behandling af btk-medierede forstyrrelser
DK3149019T3 (da) Cholan-derivater til anvendelse ved behandling og/eller forebyggelse af FXR- og TGR5/GPBAR1-formidlede sygdomme
DK3481846T3 (da) 11-substituerede 24-hydroxysteroler til anvendelse til behandling af nmda-relaterede tilstande
DK3096798T3 (da) Plasmakallikreinbindende proteiner og anvendelser deraf til behandling af hereditært angioødem
DK3362066T3 (da) Kombinationsterapi til behandling af maligniteter
DK3811943T3 (da) Forbindelse til anvendelse til behandling af øjenlidelser
DK3307296T3 (da) Timp2 til anvendelse til behandling af aldringsassocierede tilstande
DK3390390T3 (da) Bipyrazolylderivater egnede til behandling af autoimmunsygdomme
DK3054976T3 (da) Anvendelse af semaphorin-4d-bindende molekyler til behandling af aterosklerose
DK3456330T3 (da) Cortexolon-17alpha-valerat til anvendelse ved behandling af tumorer
DK3242947T3 (da) Genterapi og elektroporese til behandling af maligniteter
DK3556383T5 (da) Plasminogen til anvendelse ved behandling af diabetes
DK3302519T3 (da) Ornithodoros-moubata-komplement-inhibitor til anvendelse i behandlingen af akut graft-versus-host-sygdom
DK3532067T3 (da) Liposomal formulering til anvendelse til behandling af cancer
DK3391902T3 (da) Plasminogen til anvendelse i behandlingen af diabetisk angiokardiopati
DK3374497T3 (da) Modificerede makrofager til anvendelse i behandlingen af kræft
DK3328864T3 (da) Terapeutiske forbindelser og sammensætninger til behandling af sociale forstyrrelser og stofmisbrugsforstyrrelser
DK3154543T3 (da) PPAR-Forbindelser til anvendelse ved behandlingen af fibrotiske lidelser
DK3522904T3 (da) Flydende sammensætning til anvendelse i behandlingen af gastroesophageal reflux
DK3253208T3 (da) Kombinationsterapier til anvendelse i behandlingen af brystcancer
DK3164123T3 (da) Hidtil ukendte anvendelser af benzylidenguanidinderivater til behandling af proteopatier
DK3242888T3 (da) Opløselige fgfr3-atrapper til behandling af skeletvækstforstyrrelser