DK336685A - 2-benzyl-4-(4-pyridyl)thiazolforbindelse, farmaceutisk praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling af forbindelserne - Google Patents

2-benzyl-4-(4-pyridyl)thiazolforbindelse, farmaceutisk praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling af forbindelserne Download PDF

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Publication number
DK336685A
DK336685A DK336685A DK336685A DK336685A DK 336685 A DK336685 A DK 336685A DK 336685 A DK336685 A DK 336685A DK 336685 A DK336685 A DK 336685A DK 336685 A DK336685 A DK 336685A
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Prior art keywords
pyridyl
benzyl
compounds
procedure
connection
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DK336685A
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Danish (da)
English (en)
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DK336685D0 (da
Inventor
David A Boulton
Ihor E Kopka
Vernon L Moore
Arsenio A Pessolano
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Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK336685D0 publication Critical patent/DK336685D0/da
Publication of DK336685A publication Critical patent/DK336685A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK336685A 1984-07-25 1985-07-24 2-benzyl-4-(4-pyridyl)thiazolforbindelse, farmaceutisk praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling af forbindelserne DK336685A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/634,094 US4697012A (en) 1984-07-25 1984-07-25 Morpholino pyridyl thiazole compound

Publications (2)

Publication Number Publication Date
DK336685D0 DK336685D0 (da) 1985-07-24
DK336685A true DK336685A (da) 1986-01-26

Family

ID=24542414

Family Applications (1)

Application Number Title Priority Date Filing Date
DK336685A DK336685A (da) 1984-07-25 1985-07-24 2-benzyl-4-(4-pyridyl)thiazolforbindelse, farmaceutisk praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling af forbindelserne

Country Status (12)

Country Link
US (1) US4697012A (US20100223739A1-20100909-C00005.png)
EP (1) EP0169502B1 (US20100223739A1-20100909-C00005.png)
JP (1) JPS6137784A (US20100223739A1-20100909-C00005.png)
KR (1) KR860001105A (US20100223739A1-20100909-C00005.png)
AU (1) AU575666B2 (US20100223739A1-20100909-C00005.png)
DE (1) DE3580317D1 (US20100223739A1-20100909-C00005.png)
DK (1) DK336685A (US20100223739A1-20100909-C00005.png)
ES (1) ES8700255A1 (US20100223739A1-20100909-C00005.png)
GR (1) GR851809B (US20100223739A1-20100909-C00005.png)
IL (1) IL75823A0 (US20100223739A1-20100909-C00005.png)
PT (1) PT80833B (US20100223739A1-20100909-C00005.png)
ZA (1) ZA855581B (US20100223739A1-20100909-C00005.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0149884B1 (en) * 1983-09-09 1992-12-16 Takeda Chemical Industries, Ltd. 5-pyridyl-1,3-thiazole derivatives, their production and use
GB9201692D0 (en) * 1992-01-27 1992-03-11 Smithkline Beecham Intercredit Compounds
HUP9801057A3 (en) * 1995-05-26 2000-06-28 Bayer Ag Pyridyl-thiazoles and their use to protect plants against infections by micro-organisms
JP4662764B2 (ja) 2002-06-14 2011-03-30 メルク セローノ ソシエテ アノニム アゾールメチリデンシアニド誘導体およびそれらのタンパク質キナーゼモジュレーターとしての使用
SA04250288B1 (ar) * 2003-09-19 2008-07-19 سولفاي فارماسوتيكالز بي . في مشتقات ثيازول thiazole كمعدلات لمستقبل المكونات الكيميائية للقنب cannabinoid
US7294640B2 (en) 2004-02-06 2007-11-13 Merck & Co., Inc. Mitotic kinesin inhibitors
EP2616441B1 (en) * 2010-09-17 2019-08-07 Purdue Pharma L.P. Pyridine compounds and the uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1112128A (en) * 1965-12-22 1968-05-01 Bellon Labor Sa Roger New thiazolyl-diphenylmethane derivatives
IL28803A (en) * 1966-11-18 1974-05-16 Wyeth John & Brother Ltd Oxazole and thiazole compounds,their preparation and pharmaceutical compositions containing them
CA962269A (en) * 1971-05-05 1975-02-04 Robert E. Grahame (Jr.) Thiazoles, and their use as insecticides
US4153703A (en) * 1977-06-30 1979-05-08 Uniroyal, Inc. Method of controlling insects and acarids with certain aryl-substituted thiazoles
EP0149884B1 (en) * 1983-09-09 1992-12-16 Takeda Chemical Industries, Ltd. 5-pyridyl-1,3-thiazole derivatives, their production and use

Also Published As

Publication number Publication date
EP0169502B1 (en) 1990-10-31
DE3580317D1 (en) 1990-12-13
ZA855581B (en) 1986-03-26
IL75823A0 (en) 1985-11-29
EP0169502A3 (en) 1987-02-25
ES545439A0 (es) 1986-10-01
US4697012A (en) 1987-09-29
JPS6137784A (ja) 1986-02-22
AU575666B2 (en) 1988-08-04
PT80833B (en) 1987-05-27
DK336685D0 (da) 1985-07-24
AU4532085A (en) 1986-01-30
KR860001105A (ko) 1986-02-22
ES8700255A1 (es) 1986-10-01
EP0169502A2 (en) 1986-01-29
GR851809B (US20100223739A1-20100909-C00005.png) 1985-11-26
PT80833A (en) 1985-08-01

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