DK3294288T3 - Inhibitorer af replikation af humant papillomavirus - Google Patents

Inhibitorer af replikation af humant papillomavirus Download PDF

Info

Publication number
DK3294288T3
DK3294288T3 DK16722201.7T DK16722201T DK3294288T3 DK 3294288 T3 DK3294288 T3 DK 3294288T3 DK 16722201 T DK16722201 T DK 16722201T DK 3294288 T3 DK3294288 T3 DK 3294288T3
Authority
DK
Denmark
Prior art keywords
inhibitors
human papillomavirus
papillomavirus replication
replication
human
Prior art date
Application number
DK16722201.7T
Other languages
English (en)
Inventor
Andres Mannik
Mart Toots
Andres Tover
Ene Ustav
Mart Ustav Sr
Original Assignee
Icosagen Cell Factory Oue
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icosagen Cell Factory Oue filed Critical Icosagen Cell Factory Oue
Application granted granted Critical
Publication of DK3294288T3 publication Critical patent/DK3294288T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK16722201.7T 2015-05-11 2016-05-11 Inhibitorer af replikation af humant papillomavirus DK3294288T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562159572P 2015-05-11 2015-05-11
PCT/EP2016/060584 WO2016180892A1 (en) 2015-05-11 2016-05-11 Human papilloma virus replication inhibitors

Publications (1)

Publication Number Publication Date
DK3294288T3 true DK3294288T3 (da) 2022-01-03

Family

ID=57247862

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16722201.7T DK3294288T3 (da) 2015-05-11 2016-05-11 Inhibitorer af replikation af humant papillomavirus

Country Status (6)

Country Link
US (2) US10543218B2 (da)
EP (1) EP3294288B1 (da)
CA (1) CA2985682A1 (da)
DK (1) DK3294288T3 (da)
ES (1) ES2901978T3 (da)
WO (1) WO2016180892A1 (da)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20041248A1 (it) 2004-06-22 2004-09-22 Need Pharma S R L Impiego di composti eterociclici azotati e relative composizioni come microbicidi
WO2008062662A1 (fr) 2006-11-21 2008-05-29 Konica Minolta Opto, Inc. Procédé pour produire un substrat en verre pour un support d'enregistrement d'informations, substrat en verre pour un support d'enregistrement d'informations et support d'enregistrement d'informations
WO2008063662A2 (en) * 2006-11-21 2008-05-29 Black Lion Pharmaceuticals Gold (iii) chloride compositions for cancer
US8940740B2 (en) * 2010-10-28 2015-01-27 Southern Research Institute Small molecule inhibitors of bacterial motility and a high throughput screening assay for their identification
EP3280816A1 (en) 2015-04-09 2018-02-14 Icosagen Cell Factory OÜ Assay system to identify hpv replication inhibitors in ht-screen

Also Published As

Publication number Publication date
CA2985682A1 (en) 2016-11-17
ES2901978T3 (es) 2022-03-24
US11000529B2 (en) 2021-05-11
US20200046730A1 (en) 2020-02-13
US10543218B2 (en) 2020-01-28
EP3294288B1 (en) 2021-09-29
US20180133228A1 (en) 2018-05-17
WO2016180892A1 (en) 2016-11-17
EP3294288A1 (en) 2018-03-21

Similar Documents

Publication Publication Date Title
DK3102576T3 (da) Dihydropyrrolopyridininhibitorer af ror-gamma
DK3160956T3 (da) Inhibitorer af lysin-specifik demethylase-1
PT3286166T (pt) Inibidores de replicação do vírus da imunodeficiência humana
DK3851537T5 (da) Behandling af hyperbilirubinæmi
DK3137169T3 (da) Hæmmere af lysin-specifik demethylase-1
DK3511319T3 (da) Hæmmere af lysinspecifik demethylase-1
DK3202086T3 (da) Tilstandsreplikation af virtuelle netværksfunktionsinstanser
BR112017002231A2 (pt) novas formulações de um inibidor de tirosina cinase de bruton
DK3160470T3 (da) Analoger af pridopidin, fremstilling og anvendelse heraf
DK3116533T3 (da) Deletion af dystrophingenexon under anvendelse af genmanipulerede nukleaser
IL245213A0 (en) Inhibitors of human immunodeficiency virus replication
DK3244948T3 (da) Bestemmelse af medikamentdosis
DK3068776T3 (da) Inhibitorer af replikation af influenzavira
DK3144001T3 (da) Sammensætninger af selenoorganiske forbindelser og fremgangsmåder til anvendelse deraf
DK3227310T3 (da) Heterobifunktionelle inhibitorer af e-selektiner og cxcr4-kemokin-receptorer
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
DK3204398T3 (da) Fremgangsmåder til fraseparering af gemcitabin-phosphat diastereoisomerer
DK3307267T3 (da) Behandling af multipel sklerose
DK3164394T3 (da) Gls1-inhibitorer til behandling af sygdomme
DK3283210T3 (da) Fremgangsmåde
DK3166628T3 (da) Terapeutisk anvendelse af knoglemorfogenetiske proteiner
DK3094322T3 (da) Administration af tasimelteon i fastende tilstand
DK3390422T3 (da) Krystalformer af lnt
DK3237621T3 (da) Varianter af human alpha-galactosidase
DK3204352T3 (da) Hæmmere af lysin-gingipain