DK3269731T5 - Molekylært design af rekombinant proteinlægemiddel - Google Patents
Molekylært design af rekombinant proteinlægemiddel Download PDFInfo
- Publication number
- DK3269731T5 DK3269731T5 DK16748749.5T DK16748749T DK3269731T5 DK 3269731 T5 DK3269731 T5 DK 3269731T5 DK 16748749 T DK16748749 T DK 16748749T DK 3269731 T5 DK3269731 T5 DK 3269731T5
- Authority
- DK
- Denmark
- Prior art keywords
- recombinant protein
- protein drug
- molecular design
- molecular
- design
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1891—Angiogenesic factors; Angiogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510079486 | 2015-02-13 | ||
| CN201510736184 | 2015-11-02 | ||
| PCT/CN2016/073773 WO2016127948A1 (zh) | 2015-02-13 | 2016-02-14 | 一种重组蛋白质药物的分子设计 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3269731T3 DK3269731T3 (da) | 2023-10-30 |
| DK3269731T5 true DK3269731T5 (da) | 2024-10-14 |
Family
ID=56614147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16748749.5T DK3269731T5 (da) | 2015-02-13 | 2016-02-14 | Molekylært design af rekombinant proteinlægemiddel |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10869910B2 (enExample) |
| EP (1) | EP3269731B1 (enExample) |
| JP (1) | JP6896636B2 (enExample) |
| CN (2) | CN114249816B (enExample) |
| AU (2) | AU2016218635B2 (enExample) |
| CA (1) | CA3014538A1 (enExample) |
| DK (1) | DK3269731T5 (enExample) |
| WO (1) | WO2016127948A1 (enExample) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101890155B (zh) * | 2010-05-25 | 2012-07-25 | 江苏先声药物研究有限公司 | 一种药物组合物及其应用 |
| WO2013034116A1 (zh) * | 2011-09-09 | 2013-03-14 | 清华大学 | 对atp结合位点进行突变的血管内皮抑制素突变体 |
| CN107148277B (zh) * | 2014-11-03 | 2022-03-22 | 清华大学 | 一种抑制脂肪细胞分化和胰岛素耐受的药物 |
-
2016
- 2016-02-14 CN CN202111201002.3A patent/CN114249816B/zh active Active
- 2016-02-14 EP EP16748749.5A patent/EP3269731B1/en active Active
- 2016-02-14 US US15/550,751 patent/US10869910B2/en active Active
- 2016-02-14 CN CN201680010044.XA patent/CN107428809B/zh active Active
- 2016-02-14 DK DK16748749.5T patent/DK3269731T5/da active
- 2016-02-14 CA CA3014538A patent/CA3014538A1/en active Pending
- 2016-02-14 AU AU2016218635A patent/AU2016218635B2/en active Active
- 2016-02-14 JP JP2017542389A patent/JP6896636B2/ja active Active
- 2016-02-14 WO PCT/CN2016/073773 patent/WO2016127948A1/zh not_active Ceased
-
2020
- 2020-09-28 US US17/035,497 patent/US20210085754A1/en active Pending
- 2020-10-13 AU AU2020256316A patent/AU2020256316B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3269731A4 (en) | 2018-08-15 |
| JP6896636B2 (ja) | 2021-06-30 |
| EP3269731B1 (en) | 2023-10-04 |
| AU2020256316A1 (en) | 2020-11-12 |
| CA3014538A1 (en) | 2016-08-18 |
| AU2016218635A1 (en) | 2017-10-05 |
| CN114249816A (zh) | 2022-03-29 |
| CN114249816B (zh) | 2024-09-06 |
| CN107428809A (zh) | 2017-12-01 |
| WO2016127948A1 (zh) | 2016-08-18 |
| US20180200337A1 (en) | 2018-07-19 |
| US20210085754A1 (en) | 2021-03-25 |
| JP2018507854A (ja) | 2018-03-22 |
| AU2016218635B2 (en) | 2020-07-23 |
| AU2020256316B2 (en) | 2021-10-07 |
| US10869910B2 (en) | 2020-12-22 |
| DK3269731T3 (da) | 2023-10-30 |
| EP3269731A1 (en) | 2018-01-17 |
| CN107428809B (zh) | 2021-10-01 |
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