DK3258960T3 - Leptospira-immunbeskyttende proteiner og fremgangsmåder til identifikation og anvendelse deraf - Google Patents

Leptospira-immunbeskyttende proteiner og fremgangsmåder til identifikation og anvendelse deraf Download PDF

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Publication number
DK3258960T3
DK3258960T3 DK16719949.6T DK16719949T DK3258960T3 DK 3258960 T3 DK3258960 T3 DK 3258960T3 DK 16719949 T DK16719949 T DK 16719949T DK 3258960 T3 DK3258960 T3 DK 3258960T3
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DK
Denmark
Prior art keywords
leptospira
immune
identifying
methods
protecting proteins
Prior art date
Application number
DK16719949.6T
Other languages
English (en)
Inventor
Natalia Ines Bomchil
Jean-Baptiste Claude
Lionel Pierre Christian Cupillard
Anass Jawhari
Elodie Mandon
Angeli Kodjo
Mathieu Picardeau
Azad Eshghi
Celia Fontana
Original Assignee
Boehringer Ingelheim Animal Health Usa Inc
Calixar
Genostar
Vetagro Sup
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health Usa Inc, Calixar, Genostar, Vetagro Sup, Pasteur Institut filed Critical Boehringer Ingelheim Animal Health Usa Inc
Application granted granted Critical
Publication of DK3258960T3 publication Critical patent/DK3258960T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0208Specific bacteria not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0225Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
DK16719949.6T 2015-02-20 2016-02-22 Leptospira-immunbeskyttende proteiner og fremgangsmåder til identifikation og anvendelse deraf DK3258960T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562118790P 2015-02-20 2015-02-20
PCT/US2016/018958 WO2016134373A2 (en) 2015-02-20 2016-02-22 Leptospira immunoprotective proteins and methods of identification and use thereof

Publications (1)

Publication Number Publication Date
DK3258960T3 true DK3258960T3 (da) 2021-04-19

Family

ID=55863168

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16719949.6T DK3258960T3 (da) 2015-02-20 2016-02-22 Leptospira-immunbeskyttende proteiner og fremgangsmåder til identifikation og anvendelse deraf

Country Status (10)

Country Link
US (1) US10525117B2 (da)
EP (1) EP3258960B1 (da)
AU (1) AU2016219787B2 (da)
CA (1) CA2977353A1 (da)
DK (1) DK3258960T3 (da)
ES (1) ES2864957T3 (da)
HK (1) HK1248541A1 (da)
NZ (1) NZ734938A (da)
PT (1) PT3258960T (da)
WO (1) WO2016134373A2 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230151064A1 (en) * 2020-02-07 2023-05-18 Yale University Leptospiral proteins and uses thereof
AU2022323324A1 (en) * 2021-08-06 2024-03-21 Yale University Leptospiral virulence modulating proteins and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
WO2004032599A2 (en) 2002-10-10 2004-04-22 Cornell Research Foundation, Inc. Novel immunogenic proteins of leptospira
EP2205625B1 (en) 2007-09-24 2012-09-12 Cornell University Immunogenic proteins from genome-derived outer membrane of leptospira and compositions and methods based thereon
CN101874898A (zh) 2010-06-21 2010-11-03 严杰 预防不同血清群问号钩端螺旋体感染的通用型三价基因重组疫苗及其制备方法

Also Published As

Publication number Publication date
CA2977353A1 (en) 2016-08-25
ES2864957T3 (es) 2021-10-14
NZ734938A (en) 2019-06-28
AU2016219787A1 (en) 2017-09-14
US20170021004A1 (en) 2017-01-26
AU2016219787B2 (en) 2019-05-30
EP3258960B1 (en) 2021-01-13
HK1248541A1 (zh) 2018-10-19
WO2016134373A3 (en) 2016-11-10
PT3258960T (pt) 2021-03-31
EP3258960A2 (en) 2017-12-27
US10525117B2 (en) 2020-01-07
WO2016134373A2 (en) 2016-08-25

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