DK3240798T3 - Ny fremgangsmåde til effektiv rensning af humant serum-albumin - Google Patents

Ny fremgangsmåde til effektiv rensning af humant serum-albumin Download PDF

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Publication number
DK3240798T3
DK3240798T3 DK16732884.8T DK16732884T DK3240798T3 DK 3240798 T3 DK3240798 T3 DK 3240798T3 DK 16732884 T DK16732884 T DK 16732884T DK 3240798 T3 DK3240798 T3 DK 3240798T3
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DK
Denmark
Prior art keywords
humant
serum albumin
effective cleaning
new procedure
procedure
Prior art date
Application number
DK16732884.8T
Other languages
English (en)
Inventor
Rajyashri Ramakrishna Karur
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Application granted granted Critical
Publication of DK3240798T3 publication Critical patent/DK3240798T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • B01D15/125Pre-filtration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • B01D15/327Reversed phase with hydrophobic interaction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361Ion-exchange
    • B01D15/362Cation-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361Ion-exchange
    • B01D15/363Anion-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK16732884.8T 2015-01-01 2016-01-01 Ny fremgangsmåde til effektiv rensning af humant serum-albumin DK3240798T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3228CH2014 2015-01-01
PCT/IB2016/050001 WO2016108211A1 (en) 2015-01-01 2016-01-01 Novel method for efficient purification of human serum albumin

Publications (1)

Publication Number Publication Date
DK3240798T3 true DK3240798T3 (da) 2020-05-11

Family

ID=56284388

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16732884.8T DK3240798T3 (da) 2015-01-01 2016-01-01 Ny fremgangsmåde til effektiv rensning af humant serum-albumin

Country Status (12)

Country Link
US (2) US10377812B2 (da)
EP (1) EP3240798B8 (da)
CY (1) CY1122787T1 (da)
DK (1) DK3240798T3 (da)
ES (1) ES2780367T3 (da)
HR (1) HRP20200710T1 (da)
LT (1) LT3240798T (da)
PL (1) PL3240798T3 (da)
PT (1) PT3240798T (da)
RS (1) RS60210B1 (da)
SI (1) SI3240798T1 (da)
WO (1) WO2016108211A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10377812B2 (en) * 2015-01-01 2019-08-13 Navya Biologicals Pvt Ltd Method for efficient purification of human serum albumin
CN113461804A (zh) * 2021-08-09 2021-10-01 山东健通生物科技有限公司 减少重组人血白蛋白发酵过程中色素的方法
CN117143222A (zh) * 2023-09-11 2023-12-01 江苏帆博生物制品有限公司 一种牛血清白蛋白生产方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT382803B (de) * 1981-05-25 1987-04-10 Bucher Franz Verfahren und vorrichtung zur herstellung eines bewehrungsbuendels
IE922257A1 (en) 1991-07-12 1993-01-13 Gist Brocades Nv Process for the purification of serum albumin
FR2686620B1 (fr) * 1992-01-27 1995-06-23 Rhone Poulenc Rorer Sa Serum-albumine humaine, preparation et utilisation.
US5440018A (en) 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
CA2116385A1 (en) * 1993-02-25 1994-08-26 Akinori Sumi Human serum albumin and process for producing the same
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
ES2211889T3 (es) 1994-08-31 2004-07-16 Mitsubishi Pharma Corporation Procedimiento para la purificacion de albumina de suero recombinante.
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
CN101768206B (zh) 2008-12-31 2013-05-15 华北制药集团新药研究开发有限责任公司 一种重组人血清白蛋白的纯化方法及其应用
US10377812B2 (en) * 2015-01-01 2019-08-13 Navya Biologicals Pvt Ltd Method for efficient purification of human serum albumin

Also Published As

Publication number Publication date
US20190367582A1 (en) 2019-12-05
RS60210B1 (sr) 2020-06-30
US10981975B2 (en) 2021-04-20
PT3240798T (pt) 2020-05-07
US10377812B2 (en) 2019-08-13
ES2780367T3 (es) 2020-08-25
EP3240798A4 (en) 2018-11-14
EP3240798A1 (en) 2017-11-08
HRP20200710T1 (hr) 2020-07-24
US20170349645A1 (en) 2017-12-07
CY1122787T1 (el) 2021-05-05
EP3240798B8 (en) 2020-03-25
EP3240798B1 (en) 2020-02-12
PL3240798T3 (pl) 2020-11-02
WO2016108211A1 (en) 2016-07-07
SI3240798T1 (sl) 2020-07-31
LT3240798T (lt) 2020-04-10

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