DK3209819T3 - Genetic encoding of chemical post-translational modification for phage-displayed libraries - Google Patents
Genetic encoding of chemical post-translational modification for phage-displayed libraries Download PDFInfo
- Publication number
- DK3209819T3 DK3209819T3 DK15853468.5T DK15853468T DK3209819T3 DK 3209819 T3 DK3209819 T3 DK 3209819T3 DK 15853468 T DK15853468 T DK 15853468T DK 3209819 T3 DK3209819 T3 DK 3209819T3
- Authority
- DK
- Denmark
- Prior art keywords
- phage
- translational modification
- chemical post
- displayed libraries
- genetic encoding
- Prior art date
Links
- 230000002068 genetic effect Effects 0.000 title 1
- 230000004481 post-translational protein modification Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462067183P | 2014-10-22 | 2014-10-22 | |
| PCT/CA2015/051077 WO2016061695A1 (en) | 2014-10-22 | 2015-10-22 | Genetic encoding of chemical post-translational modification for phage-displayed libraries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3209819T3 true DK3209819T3 (da) | 2024-05-21 |
Family
ID=55759999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15853468.5T DK3209819T3 (da) | 2014-10-22 | 2015-10-22 | Genetic encoding of chemical post-translational modification for phage-displayed libraries |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10724034B2 (da) |
| EP (2) | EP4350056A3 (da) |
| JP (1) | JP6715831B2 (da) |
| AU (1) | AU2015336857B2 (da) |
| CA (1) | CA2965380A1 (da) |
| DK (1) | DK3209819T3 (da) |
| WO (1) | WO2016061695A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102521152B1 (ko) | 2016-11-16 | 2023-04-13 | 카탈로그 테크놀로지스, 인크. | 핵산-기반 데이터 저장용 시스템 |
| US20190352636A1 (en) * | 2017-01-31 | 2019-11-21 | The Governors Of The University Of Alberta | Display of molecules on silently genetically encoded nanoscale carriers for determining synergistic molecular interactions |
| CA3094077A1 (en) * | 2018-03-16 | 2019-09-19 | Catalog Technologies, Inc. | Chemical methods for nucleic acid-based data storage |
| KR20210096115A (ko) * | 2018-11-28 | 2021-08-04 | 더 거버너스 오브 더 유니버시티 오브 알버타 | 약물작용 발생단이 내재된 유전자-암호화된 거대고리형 펩타이드 라이브러리 |
| CA3143081A1 (en) | 2019-06-18 | 2020-12-24 | Eligo Bioscience | Bacterial delivery vehicles comprising tracer nucleic acid sequences |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006304110B2 (en) | 2005-10-12 | 2012-02-02 | The Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| DK2474613T3 (da) | 2008-02-05 | 2014-10-06 | Bicycle Therapeutics Ltd | Fremgangsmåder og sammensætninger |
| UA93922C2 (ru) | 2009-03-20 | 2011-03-25 | Михаил Викторович Разуменко | Способ получения пептидов, которые специфически распознают клетки определенного типа, и предназначены для терапевтических целей |
| TWI460620B (zh) | 2011-08-24 | 2014-11-11 | Pixart Imaging Inc | 人機介面裝置 |
| US20130196867A1 (en) | 2011-12-16 | 2013-08-01 | The University Of North Carolina At Chapel Hill | Combinatorial post-translationally-modified histone peptides, arrays thereof, and methods of using the same |
| EP2810069A4 (en) | 2012-02-03 | 2015-08-12 | Univ Alberta | METHOD FOR THE QUANTIFICATION OF PEPTIDE DERIVATIVE LIBRARIES BY PHAG DISPLAY |
| US10087485B2 (en) * | 2012-06-06 | 2018-10-02 | The Trustees Of Princeton University | DNA barcoding of designer mononucleosome and chromatin array libraries for the profiling of chromatin readers, writers, erasers, and modulators thereof |
-
2015
- 2015-10-22 EP EP24157340.1A patent/EP4350056A3/en active Pending
- 2015-10-22 JP JP2017522188A patent/JP6715831B2/ja active Active
- 2015-10-22 AU AU2015336857A patent/AU2015336857B2/en active Active
- 2015-10-22 EP EP15853468.5A patent/EP3209819B1/en active Active
- 2015-10-22 CA CA2965380A patent/CA2965380A1/en active Pending
- 2015-10-22 WO PCT/CA2015/051077 patent/WO2016061695A1/en active Application Filing
- 2015-10-22 US US15/520,958 patent/US10724034B2/en active Active
- 2015-10-22 DK DK15853468.5T patent/DK3209819T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015336857B2 (en) | 2020-04-09 |
| EP3209819B1 (en) | 2024-02-14 |
| AU2015336857A1 (en) | 2017-06-01 |
| EP4350056A2 (en) | 2024-04-10 |
| US20170355982A1 (en) | 2017-12-14 |
| US10724034B2 (en) | 2020-07-28 |
| EP3209819A1 (en) | 2017-08-30 |
| EP4350056A3 (en) | 2024-06-26 |
| CA2965380A1 (en) | 2016-04-28 |
| JP6715831B2 (ja) | 2020-07-01 |
| JP2017535260A (ja) | 2017-11-30 |
| WO2016061695A1 (en) | 2016-04-28 |
| EP3209819A4 (en) | 2018-05-16 |
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