DK3113778T3 - PYRIDAZINO DERIVATIVES FOR USE IN PREVENTION OR TREATMENT OF AN ATAXIC DISORDER - Google Patents

PYRIDAZINO DERIVATIVES FOR USE IN PREVENTION OR TREATMENT OF AN ATAXIC DISORDER Download PDF

Info

Publication number
DK3113778T3
DK3113778T3 DK15709324.6T DK15709324T DK3113778T3 DK 3113778 T3 DK3113778 T3 DK 3113778T3 DK 15709324 T DK15709324 T DK 15709324T DK 3113778 T3 DK3113778 T3 DK 3113778T3
Authority
DK
Denmark
Prior art keywords
ethyl
hydroxypyridazin
hydroxy
trifluoromethyl
compound
Prior art date
Application number
DK15709324.6T
Other languages
Danish (da)
English (en)
Inventor
Sarah Almond
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50554599&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3113778(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Application granted granted Critical
Publication of DK3113778T3 publication Critical patent/DK3113778T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK15709324.6T 2014-03-06 2015-03-06 PYRIDAZINO DERIVATIVES FOR USE IN PREVENTION OR TREATMENT OF AN ATAXIC DISORDER DK3113778T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1403944.0A GB201403944D0 (en) 2014-03-06 2014-03-06 New use
PCT/GB2015/050654 WO2015132608A1 (en) 2014-03-06 2015-03-06 Pyridazine derivatives for use in the prevention or treatment of an ataxic disorder

Publications (1)

Publication Number Publication Date
DK3113778T3 true DK3113778T3 (en) 2018-07-30

Family

ID=50554599

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15709324.6T DK3113778T3 (en) 2014-03-06 2015-03-06 PYRIDAZINO DERIVATIVES FOR USE IN PREVENTION OR TREATMENT OF AN ATAXIC DISORDER

Country Status (32)

Country Link
US (1) US20170014407A1 (https=)
EP (1) EP3113778B1 (https=)
JP (1) JP6510549B2 (https=)
KR (1) KR20160126081A (https=)
CN (1) CN106102743A (https=)
AU (1) AU2015225954B2 (https=)
CA (1) CA2940342A1 (https=)
CL (1) CL2016002151A1 (https=)
CY (1) CY1120573T1 (https=)
DK (1) DK3113778T3 (https=)
EA (1) EA036438B1 (https=)
ES (1) ES2676905T3 (https=)
GB (1) GB201403944D0 (https=)
GE (2) GEAP201914284A (https=)
HR (1) HRP20181082T1 (https=)
IL (1) IL247435A0 (https=)
LT (1) LT3113778T (https=)
MA (1) MA39315A1 (https=)
MX (1) MX2016010524A (https=)
MY (1) MY202127A (https=)
PH (1) PH12016501751A1 (https=)
PL (1) PL3113778T3 (https=)
PT (1) PT3113778T (https=)
RS (1) RS57594B1 (https=)
SG (1) SG11201607106YA (https=)
SI (1) SI3113778T1 (https=)
SM (1) SMT201800367T1 (https=)
TR (1) TR201809537T4 (https=)
TW (1) TW201534591A (https=)
UA (1) UA123352C2 (https=)
WO (1) WO2015132608A1 (https=)
ZA (1) ZA201604611B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3115B1 (ar) 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao
GB201222711D0 (en) 2012-12-17 2013-01-30 Takeda Pharmaceutical Novel compounds
PT3137456T (pt) 2014-04-29 2021-08-06 Fmc Corp Herbicidas de piridazinona
TWI785022B (zh) 2017-03-28 2022-12-01 美商富曼西公司 新穎噠嗪酮類除草劑
US11213030B2 (en) 2017-06-30 2022-01-04 Fmc Corporation 4-(3,4-dihydronaphth-1-yl or 2H-chromen-4-yl)-5-hydroxy-2H-pyradizin-3-ones as herbicides
CN112569217B (zh) * 2019-09-30 2022-04-22 厦门大学 戊酸衍生物在治疗遗传性小脑共济失调中的应用
JP2021138648A (ja) 2020-03-04 2021-09-16 武田薬品工業株式会社 経口固形製剤
PE20232048A1 (es) 2021-03-01 2023-12-27 Neurocrine Biosciences Inc Uso de luvadaxistat para el tratamiento de deterioro cognitivo

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2262322T3 (es) * 1998-06-10 2006-11-16 Meiji Seika Kaisha, Ltd. Tratamiento de la degenaracion espinocereberal y comoposiciones utiles para el tratamiento de degeneracion espinocerebelar.
AU2002339696A1 (en) * 2001-12-03 2003-06-17 Genset S.A. Treatment of cns disorders using d-amino acid oxidase and d-aspartate oxidase inhibitors
JO3115B1 (ar) * 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao

Also Published As

Publication number Publication date
GB201403944D0 (en) 2014-04-23
ES2676905T3 (es) 2018-07-26
SG11201607106YA (en) 2016-09-29
EA036438B1 (ru) 2020-11-11
UA123352C2 (uk) 2021-03-24
PL3113778T3 (pl) 2018-11-30
GEP20196984B (en) 2019-06-25
SMT201800367T1 (it) 2018-09-13
JP6510549B2 (ja) 2019-05-08
RS57594B1 (sr) 2018-11-30
TW201534591A (zh) 2015-09-16
PT3113778T (pt) 2018-07-11
EA201691566A1 (ru) 2016-12-30
PH12016501751A1 (en) 2017-02-06
US20170014407A1 (en) 2017-01-19
CA2940342A1 (en) 2015-09-11
AU2015225954A1 (en) 2016-07-07
EP3113778A1 (en) 2017-01-11
IL247435A0 (en) 2016-11-30
LT3113778T (lt) 2018-08-27
CN106102743A (zh) 2016-11-09
EP3113778B1 (en) 2018-06-06
MA39315A1 (fr) 2017-09-29
CL2016002151A1 (es) 2016-12-30
KR20160126081A (ko) 2016-11-01
WO2015132608A1 (en) 2015-09-11
HRP20181082T1 (hr) 2018-09-07
TR201809537T4 (tr) 2018-07-23
JP2017507156A (ja) 2017-03-16
AU2015225954B2 (en) 2020-06-18
SI3113778T1 (en) 2018-08-31
ZA201604611B (en) 2017-09-27
CY1120573T1 (el) 2019-07-10
GEAP201914284A (en) 2019-02-25
MY202127A (en) 2024-04-05
MX2016010524A (es) 2016-10-31

Similar Documents

Publication Publication Date Title
DK3113778T3 (en) PYRIDAZINO DERIVATIVES FOR USE IN PREVENTION OR TREATMENT OF AN ATAXIC DISORDER
JP5675650B2 (ja) 向精神薬の働きを向上させるソルビン酸、安息香酸及びその誘導体
West et al. Transient inactivation of basolateral amygdala during selective satiation disrupts reinforcer devaluation in rats.
EP1408976B3 (en) Treatment for attention-deficit hyperactivity disorder
AU2002322539A1 (en) Treatment for attention-deficit hyperactivity disorder
EA014576B1 (ru) Комбинированные препараты, содержащие бифепрунокс и l-допу
Eckley et al. Acepromazine and chlorpromazine as pharmaceutical-grade alternatives to chlorprothixene for pupillary light reflex imaging in mice
Barr et al. Repeated electroconvulsive shock attenuates the depressive-like effects of d-amphetamine withdrawal on brain reward function in rats
HK1230925A1 (en) Pyridazine derivatives for use in the prevention or treatment of an ataxic disorder
Júnior et al. Effects of constant intravenous infusion of detomidine alone or combined with butorphanol or methadone for standing sedation in horses: a randomized clinical trial
US20080318926A1 (en) Methods of Treating Mood Disorders Using Pyridyloxymethyl and Benzisoxazole Azabicyclic Derivatives
WO2022079304A1 (en) Compositions and uses thereof
CN107648235B (zh) 普纳替尼在制备治疗缺血/再灌注损伤药物中的应用
Vets et al. SAGI DENENBERG
Evans THE CHALLENGE
EP4208161A1 (en) Compositions and uses thereof
US20230062537A1 (en) Therapy of oxygen pulses for treating neurodegenerative disorders such as Parkinson Disease (PD), Alzheimer’s Disease (AD), Amiotrophic Lateral Sclerosis (ALS) or Motor Neuron Disease (MND) and other dementias, and Lymphedema, Arthritis and Depression
Brumley The ontogeny of interlimb coordination during serotonin-induced hindlimb stepping in the perinatal rat
Cole Highlights from the 14th International Congress of Parkinson´ s Disease and Movement Disorders: Future treatments
McFadden The long-term effects of dopaminergic manipulations in the preadolescent rodent
Hunter Glutamate and escape performance in a neurometabolic stress conception of helplessness
UA9407U (en) Method for treating diabetic retinopathy