DK3030231T3 - Ketonlegeme og ketonlegemeester til reducering af muskelnedbrydning - Google Patents

Ketonlegeme og ketonlegemeester til reducering af muskelnedbrydning Download PDF

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Publication number
DK3030231T3
DK3030231T3 DK14750206.6T DK14750206T DK3030231T3 DK 3030231 T3 DK3030231 T3 DK 3030231T3 DK 14750206 T DK14750206 T DK 14750206T DK 3030231 T3 DK3030231 T3 DK 3030231T3
Authority
DK
Denmark
Prior art keywords
ketone body
reducing muscle
master
muscle breakdown
ketone
Prior art date
Application number
DK14750206.6T
Other languages
English (en)
Inventor
Kieran Clarke
Peter Cox
Original Assignee
Tdeltas Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tdeltas Ltd filed Critical Tdeltas Ltd
Application granted granted Critical
Publication of DK3030231T3 publication Critical patent/DK3030231T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/121Ketones acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK14750206.6T 2013-08-07 2014-08-07 Ketonlegeme og ketonlegemeester til reducering af muskelnedbrydning DK3030231T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1314127.0A GB201314127D0 (en) 2013-08-07 2013-08-07 Ketone body and ketone body ester for reducing muscle breakdown
PCT/EP2014/067027 WO2015018913A1 (en) 2013-08-07 2014-08-07 Ketone body and ketone body ester for reducing muscle breakdown

Publications (1)

Publication Number Publication Date
DK3030231T3 true DK3030231T3 (da) 2021-09-13

Family

ID=49224294

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14750206.6T DK3030231T3 (da) 2013-08-07 2014-08-07 Ketonlegeme og ketonlegemeester til reducering af muskelnedbrydning

Country Status (10)

Country Link
US (1) US20150065571A1 (da)
EP (1) EP3030231B1 (da)
AU (4) AU2014304481A1 (da)
CA (1) CA2919778C (da)
DK (1) DK3030231T3 (da)
ES (1) ES2885678T3 (da)
GB (2) GB201314127D0 (da)
HK (1) HK1225965A1 (da)
SG (1) SG11201600419QA (da)
WO (1) WO2015018913A1 (da)

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CA2527940C (en) 2003-06-03 2016-03-22 Richard L. Veech Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives
EP2240017B1 (en) 2008-01-04 2019-03-13 Oxford University Innovation Limited Ketone bodies and ketone body esters as blood lipid lowering agents
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
GB201002983D0 (en) 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition
ES2752030T3 (es) 2012-11-05 2020-04-02 Us Health Cuerpos cetónicos para proteger los tejidos del daño por radiación ionizante
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
AU2014230120B2 (en) 2013-03-14 2018-06-21 Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Process for producing (R)-3hydroxybutyl (R)-3hydroxybutyrate
US9255059B2 (en) 2013-08-02 2016-02-09 Eastman Chemical Company Method for producing an alkyl 3-hydroxybutyrate
US9388114B2 (en) 2013-08-02 2016-07-12 Eastman Chemical Company Compositions including an alkyl 3-hydroxybutyrate
US9249378B2 (en) 2013-08-02 2016-02-02 Eastman Chemical Company Aqueous cleaning compositions having enhanced properties
US9163202B2 (en) 2013-08-02 2015-10-20 Eastman Chemical Company Aqueous cleaning compositions including an alkyl 3-hydroxybutyrate
US11103470B2 (en) 2017-11-22 2021-08-31 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US10736861B2 (en) 2016-03-11 2020-08-11 Axcess Global Sciences, Llc Mixed salt compositions for producing elevated and sustained ketosis
US10973792B2 (en) 2019-02-13 2021-04-13 Axcess Global Sciences, Llc Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use
US11185518B2 (en) 2017-12-19 2021-11-30 Axcess Global Sciences, Llc S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer
US10973786B2 (en) 2016-03-11 2021-04-13 Axcess Global Sciences, Llc R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions
US11241403B2 (en) 2016-03-11 2022-02-08 Axcess Global Sciences, Llc Beta-hydroxybutyrate mixed salt compositions and methods of use
US20190099394A1 (en) * 2016-03-21 2019-04-04 Csilla Ari D'Agostino Methods of improving motor function using ketone supplementation
US11026929B2 (en) 2016-04-19 2021-06-08 Keto Patent Group, Inc. Administration of berberine metabolites
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US20180057846A1 (en) 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
KR20190099469A (ko) * 2016-12-23 2019-08-27 카트호리이케 유니버시타이트 로이펜 중환자 치료의 처치에서 사용하기 위한 단독으로의 또는 조합으로의 3-히드록시부티레이트
US20180177753A1 (en) * 2016-12-23 2018-06-28 Neuroenergy Ventures, Inc. Glyceryl 3-hydroxybutyrates for migraine symptom management
US11760963B2 (en) * 2017-08-23 2023-09-19 KetoneAid Inc. Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol
GB201715654D0 (en) 2017-09-27 2017-11-08 Tdeltas Ltd Method of treatment
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US11452704B2 (en) * 2017-11-30 2022-09-27 University Of South Florida Prevention and treatment of muscle wasting with ketone supplementation
US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US11419836B2 (en) 2019-02-13 2022-08-23 Axcess Global Sciences, Llc Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions
US11129802B2 (en) 2018-08-27 2021-09-28 Axcess Global Sciences, Llc Compositions and methods for delivering cannabidiol and ketone bodies
US11241401B2 (en) 2020-02-06 2022-02-08 Axcess Global Sciences, Llc Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions
US10980772B2 (en) 2018-08-27 2021-04-20 Axcess Global Sciences, Llc Compositions and methods for delivering tetrahydrocannabinol and ketone bodies
US11806324B2 (en) * 2018-04-18 2023-11-07 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies
GB2575623B (en) * 2018-06-04 2022-10-26 Tdeltas Ltd 3-hydroxybutyrate esters for treating cancer cachexia
CN112203650A (zh) * 2018-06-21 2021-01-08 雀巢产品有限公司 使用烟酰胺腺嘌呤二核苷酸(nad+)前体和至少一种酮或酮前体的组合物和方法
GB2577723A (en) * 2018-10-04 2020-04-08 Tdeltas Ltd Compounds for new use
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11033553B2 (en) 2019-06-21 2021-06-15 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
GB201918657D0 (en) 2019-12-17 2020-01-29 Tdeltas Ltd Compounds for new use
US20230157323A1 (en) * 2021-11-19 2023-05-25 Ketoneaid, Inc. Ketone beverage containing a slow carbohydrate
GB202219317D0 (en) * 2022-12-20 2023-02-01 Amazentis Sa Methods for improving mitophagy in subjects
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance

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WO1987003806A1 (en) * 1985-12-18 1987-07-02 Veech Richard L Parenteral nutrition therapy with amino acids
EP2283834B1 (en) * 1997-03-17 2016-07-13 BTG International Limited Therapeutic compositions comprising ketone bodies or their precursors
EP1641444B1 (en) * 2003-06-02 2016-03-23 Isis Innovation Limited Treatment of muscle fatigue
CA2527940C (en) * 2003-06-03 2016-03-22 Richard L. Veech Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives
JP5773870B2 (ja) * 2008-08-21 2015-09-02 アイシス イノヴェイション リミテッド ヒドロキシ酪酸エステル及びその医学的使用
GB201002983D0 (en) * 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition
GB201206192D0 (en) * 2012-04-05 2012-05-23 Tdeltas Ltd Ketone bodies and ketone body esters and for maintaining or improving muscle power output
CN105050594B (zh) * 2013-03-19 2019-11-12 南佛罗里达大学 用于产生升高和持久的酮症的组合物和方法

Also Published As

Publication number Publication date
GB201414016D0 (en) 2014-09-24
GB201314127D0 (en) 2013-09-18
AU2014304481A1 (en) 2016-02-11
WO2015018913A1 (en) 2015-02-12
EP3030231B1 (en) 2021-06-23
ES2885678T3 (es) 2021-12-15
CA2919778C (en) 2022-07-19
HK1225965A1 (zh) 2017-09-22
AU2021240302A1 (en) 2021-10-28
CA2919778A1 (en) 2015-02-12
GB2517088B (en) 2017-11-29
AU2019283843A1 (en) 2020-01-16
SG11201600419QA (en) 2016-02-26
AU2021240302B2 (en) 2023-09-14
EP3030231A1 (en) 2016-06-15
US20150065571A1 (en) 2015-03-05
AU2023282251A1 (en) 2024-01-18
GB2517088A (en) 2015-02-11

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