DK3019525T3 - Antistoffer til beta2-glycoprotein i og terapeutiske anvendelser deraf - Google Patents

Antistoffer til beta2-glycoprotein i og terapeutiske anvendelser deraf Download PDF

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Publication number
DK3019525T3
DK3019525T3 DK14741228.2T DK14741228T DK3019525T3 DK 3019525 T3 DK3019525 T3 DK 3019525T3 DK 14741228 T DK14741228 T DK 14741228T DK 3019525 T3 DK3019525 T3 DK 3019525T3
Authority
DK
Denmark
Prior art keywords
antibodies
therapeutic uses
beta2 glycoprotein
beta2
glycoprotein
Prior art date
Application number
DK14741228.2T
Other languages
English (en)
Inventor
Francesco Tedesco
Pier Luigi Meroni
Daniele Sblattero
Original Assignee
Onconox Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onconox Aps filed Critical Onconox Aps
Application granted granted Critical
Publication of DK3019525T3 publication Critical patent/DK3019525T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK14741228.2T 2013-07-10 2014-07-07 Antistoffer til beta2-glycoprotein i og terapeutiske anvendelser deraf DK3019525T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361844505P 2013-07-10 2013-07-10
PCT/EP2014/064400 WO2015004038A1 (en) 2013-07-10 2014-07-07 ANTIBODIES TO β2-GLYCOPROTEIN I AND THERAPEUTIC USES THEREOF

Publications (1)

Publication Number Publication Date
DK3019525T3 true DK3019525T3 (da) 2019-07-01

Family

ID=51211192

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14741228.2T DK3019525T3 (da) 2013-07-10 2014-07-07 Antistoffer til beta2-glycoprotein i og terapeutiske anvendelser deraf

Country Status (7)

Country Link
US (1) US9777057B2 (da)
EP (1) EP3019525B1 (da)
JP (1) JP6440036B2 (da)
CA (1) CA2917661C (da)
DK (1) DK3019525T3 (da)
ES (1) ES2729317T3 (da)
WO (1) WO2015004038A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10098960B2 (en) 2015-04-03 2018-10-16 Ucl Business Plc Polymer conjugate
CN114716547B (zh) * 2022-05-18 2023-11-21 珠海丽禾医疗诊断产品有限公司 一种包括抗原结合结构域的结合蛋白及其生产方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9809839D0 (en) * 1998-05-09 1998-07-08 Glaxo Group Ltd Antibody
IL125262A0 (en) 1998-07-07 1999-03-12 Yeda Res & Dev Synthetic peptides and pharmaceutical compositions comprising them
CN102816238A (zh) 2011-07-28 2012-12-12 江苏大学 IgG1型抗人β2糖蛋白I单克隆抗体及其制备和应用

Also Published As

Publication number Publication date
CA2917661C (en) 2023-09-12
US9777057B2 (en) 2017-10-03
JP2016531092A (ja) 2016-10-06
EP3019525B1 (en) 2019-04-17
WO2015004038A1 (en) 2015-01-15
CA2917661A1 (en) 2015-01-15
US20160152696A1 (en) 2016-06-02
EP3019525A1 (en) 2016-05-18
JP6440036B2 (ja) 2018-12-19
ES2729317T3 (es) 2019-10-31

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