DK2986313T3 - Stabile, protraherendede glp-1/glucagonreceptor-co-agonister til medicinsk anvendelse - Google Patents
Stabile, protraherendede glp-1/glucagonreceptor-co-agonister til medicinsk anvendelseInfo
- Publication number
- DK2986313T3 DK2986313T3 DK14719715.6T DK14719715T DK2986313T3 DK 2986313 T3 DK2986313 T3 DK 2986313T3 DK 14719715 T DK14719715 T DK 14719715T DK 2986313 T3 DK2986313 T3 DK 2986313T3
- Authority
- DK
- Denmark
- Prior art keywords
- protrahering
- glp
- agonists
- stable
- medical use
- Prior art date
Links
- 108010063919 Glucagon Receptors Proteins 0.000 title 1
- 102100040890 Glucagon receptor Human genes 0.000 title 1
- 108010086246 Glucagon-Like Peptide-1 Receptor Proteins 0.000 title 1
- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title 1
- 102100040918 Pro-glucagon Human genes 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13164272 | 2013-04-18 | ||
| US201361814969P | 2013-04-23 | 2013-04-23 | |
| EP13196656 | 2013-12-11 | ||
| PCT/EP2014/058084 WO2014170496A1 (en) | 2013-04-18 | 2014-04-22 | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2986313T3 true DK2986313T3 (da) | 2019-08-12 |
Family
ID=67547758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14719715.6T DK2986313T3 (da) | 2013-04-18 | 2014-04-22 | Stabile, protraherendede glp-1/glucagonreceptor-co-agonister til medicinsk anvendelse |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JP2019167361A (da) |
| DK (1) | DK2986313T3 (da) |
| ES (1) | ES2754048T3 (da) |
| HR (1) | HRP20191258T1 (da) |
| HU (1) | HUE045573T2 (da) |
| IL (1) | IL241762B (da) |
| PT (1) | PT2986313T (da) |
| SA (1) | SA515370004B1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025073288A1 (en) * | 2023-10-03 | 2025-04-10 | Innovent Biologics (Suzhou) Co., Ltd. | Methods of treating adolescent obesity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110039230A (ko) * | 2008-06-17 | 2011-04-15 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 생리학적 ｐＨ 완충액에서 강화된 용해도 및 안정성을 나타내는 글루카곤 유사체 |
| EP2552950A1 (en) * | 2010-03-26 | 2013-02-06 | Novo Nordisk A/S | Novel glucagon analogues |
| CN104093735B (zh) * | 2011-09-23 | 2018-07-06 | 诺沃—诺迪斯克有限公司 | 新的胰高血糖素类似物 |
| MY174727A (en) * | 2013-04-18 | 2020-05-11 | Novo Nordisk As | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
-
2014
- 2014-04-22 HU HUE14719715A patent/HUE045573T2/hu unknown
- 2014-04-22 DK DK14719715.6T patent/DK2986313T3/da active
- 2014-04-22 ES ES14719715T patent/ES2754048T3/es active Active
- 2014-04-22 HR HRP20191258TT patent/HRP20191258T1/hr unknown
- 2014-04-22 PT PT14719715T patent/PT2986313T/pt unknown
-
2015
- 2015-09-21 IL IL241762A patent/IL241762B/en not_active IP Right Cessation
- 2015-10-14 SA SA515370004A patent/SA515370004B1/ar unknown
-
2019
- 2019-05-22 JP JP2019096049A patent/JP2019167361A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20191258T1 (hr) | 2019-10-18 |
| ES2754048T3 (es) | 2020-04-15 |
| PT2986313T (pt) | 2019-09-10 |
| IL241762B (en) | 2020-03-31 |
| JP2019167361A (ja) | 2019-10-03 |
| SA515370004B1 (ar) | 2018-04-15 |
| HUE045573T2 (hu) | 2020-01-28 |
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