DK2804634T3 - Kromatografiske medier til oplagring og indgivelse af terapeutiske biologiske stoffer og små molekyler - Google Patents

Kromatografiske medier til oplagring og indgivelse af terapeutiske biologiske stoffer og små molekyler Download PDF

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Publication number
DK2804634T3
DK2804634T3 DK13739077T DK13739077T DK2804634T3 DK 2804634 T3 DK2804634 T3 DK 2804634T3 DK 13739077 T DK13739077 T DK 13739077T DK 13739077 T DK13739077 T DK 13739077T DK 2804634 T3 DK2804634 T3 DK 2804634T3
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DK
Denmark
Prior art keywords
therapeutical
administration
storage
small molecules
biological materials
Prior art date
Application number
DK13739077T
Other languages
Danish (da)
English (en)
Inventor
John A Chickosky
Charles H Honeyman
Molly S Mcglaughlin
Amro Ragheb
Original Assignee
Merck Millipore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Millipore Ltd filed Critical Merck Millipore Ltd
Application granted granted Critical
Publication of DK2804634T3 publication Critical patent/DK2804634T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK13739077T 2012-01-19 2013-01-18 Kromatografiske medier til oplagring og indgivelse af terapeutiske biologiske stoffer og små molekyler DK2804634T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261588312P 2012-01-19 2012-01-19
PCT/US2013/022057 WO2013109825A1 (en) 2012-01-19 2013-01-18 Chromatographic media for storage and delivery of therapeutic biologics and small molecules

Publications (1)

Publication Number Publication Date
DK2804634T3 true DK2804634T3 (da) 2019-11-04

Family

ID=48797397

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13739077T DK2804634T3 (da) 2012-01-19 2013-01-18 Kromatografiske medier til oplagring og indgivelse af terapeutiske biologiske stoffer og små molekyler

Country Status (10)

Country Link
US (2) US20130189322A1 (cg-RX-API-DMAC7.html)
EP (1) EP2804634B1 (cg-RX-API-DMAC7.html)
JP (2) JP6552822B2 (cg-RX-API-DMAC7.html)
KR (1) KR102113296B1 (cg-RX-API-DMAC7.html)
AU (1) AU2013209620B2 (cg-RX-API-DMAC7.html)
CA (2) CA3124806C (cg-RX-API-DMAC7.html)
DK (1) DK2804634T3 (cg-RX-API-DMAC7.html)
ES (1) ES2750211T3 (cg-RX-API-DMAC7.html)
IN (1) IN2014DN06817A (cg-RX-API-DMAC7.html)
WO (1) WO2013109825A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN02055A (cg-RX-API-DMAC7.html) 2012-09-17 2015-08-14 Grace W R & Co
US9738683B2 (en) 2013-07-25 2017-08-22 Bio-Rad Laboratories, Inc. Enhanced functionality and delivery of a protein from a porous substrate
FR3012978A1 (fr) * 2013-11-12 2015-05-15 Biocarecell Filtre biocompatible et procede de fabrication d'un filtre biocompatible.
EP3094390B1 (en) 2014-01-16 2021-07-07 W.R. Grace & CO. - CONN. Affinity chromatography media and chromatography devices
PL3137209T3 (pl) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego
IS3008B (is) * 2014-05-14 2018-12-15 Calor ehf Stöðgandi lausnir fyrir prótín og peptíð
PL3302784T3 (pl) 2015-06-05 2022-01-17 W.R. Grace & Co.-Conn. Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania
CA3097058A1 (en) * 2018-04-16 2019-10-24 Merck Patent Gmbh Additives for protein formulations to improve thermal stability

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059654A (en) * 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
DE3682047D1 (de) * 1985-07-09 1991-11-21 Quadrant Bioresources Ltd Beschuetzung von proteinen und aehnlichem.
CA2073511A1 (en) * 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5159049A (en) * 1991-04-22 1992-10-27 Allen Robert C Method for stabilizing polyacrylamide gels
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
US6284282B1 (en) * 1998-04-29 2001-09-04 Genentech, Inc. Method of spray freeze drying proteins for pharmaceutical administration
SE9904475D0 (sv) * 1999-12-08 1999-12-08 Artursson Nucleic acid delivery system
US6896894B2 (en) * 2001-10-30 2005-05-24 Battelle Memorial Institute Proteins stabilized with polysaccharide gums
JP2005517012A (ja) * 2002-02-08 2005-06-09 アルカーメス コントロールド セラピューティクス,インコーポレイテッド 持続放出のためのポリマーベース組成物
US20040137004A1 (en) * 2002-03-19 2004-07-15 Glenn Gregory M Patch for transcutaneous immunization
US6666281B2 (en) 2002-03-19 2003-12-23 Deere & Company Bearing guard for a ground-working implement
ATE448866T1 (de) 2003-02-19 2009-12-15 Natrix Separations Inc Geträgerte poröse gele umfassende verbundmaterialien
US7785769B2 (en) * 2003-07-25 2010-08-31 The United States of America as reprsented by the Secretary of the Navy Immobilization of oligonucleotides and proteins in sugar-containing hydrogels
US8182694B2 (en) 2004-04-08 2012-05-22 Natrix Separations Inc. Membrane stacks
EP1758937B1 (en) * 2004-05-24 2009-09-02 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
EP1773485B1 (en) * 2004-06-07 2015-09-16 Natrix Separations Inc. Stable composite material comprising supported porous gels

Also Published As

Publication number Publication date
AU2013209620B2 (en) 2017-06-15
CA3124806C (en) 2023-09-26
US20200069602A1 (en) 2020-03-05
EP2804634A4 (en) 2015-07-22
EP2804634B1 (en) 2019-08-28
CA2861932C (en) 2021-09-14
KR20140117529A (ko) 2014-10-07
JP2015504092A (ja) 2015-02-05
WO2013109825A1 (en) 2013-07-25
ES2750211T3 (es) 2020-03-25
CA3124806A1 (en) 2013-07-27
KR102113296B1 (ko) 2020-06-02
JP6552822B2 (ja) 2019-07-31
EP2804634A1 (en) 2014-11-26
US20130189322A1 (en) 2013-07-25
AU2013209620A1 (en) 2014-08-28
CA2861932A1 (en) 2013-07-27
JP2019011341A (ja) 2019-01-24
IN2014DN06817A (cg-RX-API-DMAC7.html) 2015-05-22

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