DK2744424T3 - Adaptivt roterende kateter til åbning af tilstoppede kar i kroppen - Google Patents

Adaptivt roterende kateter til åbning af tilstoppede kar i kroppen Download PDF

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Publication number
DK2744424T3
DK2744424T3 DK12823939.9T DK12823939T DK2744424T3 DK 2744424 T3 DK2744424 T3 DK 2744424T3 DK 12823939 T DK12823939 T DK 12823939T DK 2744424 T3 DK2744424 T3 DK 2744424T3
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DK
Denmark
Prior art keywords
tip
hollow shaft
vessel
distal end
rotating catheter
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DK12823939.9T
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English (en)
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Samuel Shiber
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Samuel Shiber
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Publication of DK2744424T3 publication Critical patent/DK2744424T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320758Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • A61B2017/22047Means for immobilising the guide wire in the patient
    • A61B2017/22048Balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22065Functions of balloons
    • A61B2017/22068Centering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22065Functions of balloons
    • A61B2017/22071Steering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320758Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
    • A61B2017/320766Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven eccentric
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08Accessories or related features not otherwise provided for
    • A61B2090/0801Prevention of accidental cutting or pricking
    • A61B2090/08021Prevention of accidental cutting or pricking of the patient or his organs

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)

Claims (14)

1. Roterende kateter (10) til åbning af en obstruktion (11) i et kropskar (12), omfattende i kombination; en motordrevet fleksibel hulaksel (14), der er anbragt drejeligt i en fleksibel slange (13), en aspirationskanal defineret mellem en indvendig diameter af den fleksible slange og en udvendig diameter af hulakslen, hvor mindst et distal afsnit af hulakslen kan bevæge sig frit radialt i aspirationskanalen, hvorved det gøres muligt for aspirationskanalen at indtage partikler, som er lige så store som, eller mindre end, en forskel mellem den indvendige og den udvendige diameter, hvor en relativ bevægelse mellem den roterende hulaksel og den fleksible slange gør det lettere for partiklerne at bevæge sig gennem aspirationskanalen og forhindrer partiklerne i at tilstoppe aspirationskanalen, a spids (20) kendetegnet ved, at den har et tilspidset tværsnit, hvor spidsen er fastgjort til en distal ende (39) af hulakslen, hvor spidsen har en rundet distal ende (36), hvor den rundede distale ende (36) af spidsen (20) definerer en boring (18), der er tilpasset til at passe ind over en føringstråd (15), hvor hulakslen og spidsen kan rotere og glide hen over føringstråden, hvor spidsen også har en første side (22) over for en anden side (24), hvor den første side er tilpasset til at ramme obstruktionen, når spidsen roterer i en første retning (40), hvor den første (22) og den anden side (24) er en tværsnitsafstand (91) fra hinanden for at definere en bredde af spidsen (20), hvor spidsen også har en basisdel (26) og en modsat krone (27), som er tilpasset til at glide atraumatisk mod en væg af karret, når spidsen roterer uden for den fleksible slange, hvor basisdelen (26) og den modsatte krone (27) er en tværsnitsafstand (90) væk for at definere en højde af spidsen (20), hvor kronen er forskudt (89) væk fra en længdeakse af hulakslen længere, end basisdelen er forskudt (88) væk fra længdeaksen, hvor bredden er mindre end højden.
2. Roterende kateter (10) ifølge krav 1, hvor føringstråden (15) kan trækkes tilbage proksimalt ud over en distal ende (36) af spidsen, og den roterende krone (27) glider mod væggen af karret (12) og forskyder den distale ende (36) af spidsen væk fra væggen af karret (13).
3. Roterende kateter ifølge krav 1, hvor mindst et distalt afsnit af hulakslen omfatter en spirallignende tråd.
4. Roterende kateter ifølge krav 1, hvor en distal endesektion (17) af hulakslen (14) er udstrakt ud af den distale ende af den fleksible slange (13) og er formet på forhånd til automatisk at indtage en buet form og øge en forskydning af spidsen som en reaktion på, at føringstråden trækkes tilbage inde fra den distale endesektion af hulakslen.
5. Roterende kateter ifølge krav 1, hvor aspirationskanalen er forbundet med et sugemiddel (37) ved hjælp af en boring (59), i hvilken en tæt siddende spiral (94), som er fastgjort til hulakslen (14), er anbragt drejeligt og er tilpasset til automatisk at muliggøre bevægelse af væske og partikler, når hulakslen og spiralen roterer, og til automatisk at modstå bevægelsen, når hulakslen og spiralen befinder sig i ro.
6. Roterende kateter ifølge krav 3, hvor den spirallignende tråd roteres i en retning, således at den spirallignende tråd transporterer partikler i overstørrelse distalt.
7. Roterende kateter ifølge et af kravene 1 til 5, hvor den fleksible slange (13) kan glide i forhold til hulakslen (14).
8. Roterende kateter ifølge et af kravene 1 til 5, hvor den fleksible slange (13) glides distalt, i forhold til hulakslen, for at reducere en spalte mellem en kant af den fleksible slange (13e) og spidsen for at forhindre kanten i at gå i indgreb med væggen af karret (12), mens det roterende kateter fremføres distalt i karret.
9. Roterende kateter ifølge et af kravene 1 til 5, hvor den fleksible slange (13) valgfrit kan glides distalt eller proksimalt, i forhold til hulakslen (14), for at afskærme spidsen (20) eller for at strække den ud af den distale ende af den fleksible slange, respektivt.
10. Roterende kateter ifølge et af kravene 1 til 5, hvor hulakslen (14) er roter-bar, frem og tilbage, i den første retning og en anden rotationsretning.
11. Roterende kateter ifølge et af kravene 1 til 5, hvor den anden side (24) er tilpasset til at ramme obstruktionen, når hulakslen roteres i den anden retning (41).
12. Roterende kateter ifølge krav 3, hvor en fleksibel føringstrådbeklædning (60) er anbragt i det mindste i et distalt afsnit af den spirallignende tråd.
13. Roterende kateter ifølge et af kravene 1 til 5, hvor den første side (22) og den anden side (24) er parallelle eller let buede eller vippede fra den parallelle position.
14. Roterende kateter ifølge krav 1, hvor det tilspidsede tværsnit lader aspirationspassager (22') og (24') være åbne langs med siderne henholdsvis (22) og (24).
DK12823939.9T 2011-08-17 2012-08-14 Adaptivt roterende kateter til åbning af tilstoppede kar i kroppen DK2744424T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161575289P 2011-08-17 2011-08-17
US201261686864P 2012-04-13 2012-04-13
PCT/US2012/050759 WO2013025697A1 (en) 2011-08-17 2012-08-14 Adaptive rotary catheter for opening obstructed bodily vessels

Publications (1)

Publication Number Publication Date
DK2744424T3 true DK2744424T3 (da) 2018-01-22

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US (1) US9700347B2 (da)
EP (1) EP2744424B1 (da)
DK (1) DK2744424T3 (da)
ES (1) ES2657019T3 (da)
WO (1) WO2013025697A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013025697A1 (en) * 2011-08-17 2013-02-21 Samuel Shiber Adaptive rotary catheter for opening obstructed bodily vessels
US9907567B2 (en) 2010-05-04 2018-03-06 Samuel Shiber Mechanical — pharmaceutical system for opening obstructed bodily vessels
US10952764B2 (en) 2010-05-04 2021-03-23 Samuel Shiber Rotary catheter drive unit containing seal-sets
US20150094733A1 (en) 2010-05-04 2015-04-02 Samuel Shiber Rotary catheter drive unit containing seal-sets
US9585667B2 (en) * 2010-11-15 2017-03-07 Vascular Insights Llc Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein
US20150094749A1 (en) * 2013-03-14 2015-04-02 Cardiovascular Systems, Inc. Devices, systems and methods for a piloting tip bushing for rotational atherectomy
US10271869B2 (en) 2014-03-01 2019-04-30 Rex Medical, L.P. Atherectomy device
US20160038341A1 (en) * 2014-08-08 2016-02-11 Acclarent, Inc. Tympanostomy tube delivery device with elastomeric brake
US10039493B2 (en) * 2014-08-13 2018-08-07 St. Jude Medical Coordination Center Bvba Sensor guide wire assembly with button-cell type battery
WO2016094386A1 (en) * 2014-12-11 2016-06-16 Cardiovascular Systems, Inc. Devices, systems and methods for a piloting tip bushing for rotational atherectomy
US10463389B2 (en) 2014-12-27 2019-11-05 Rex Medical, L.P. Atherectomy device
US10433868B2 (en) 2014-12-27 2019-10-08 Rex Medical, L.P. Artherectomy device
US11253292B2 (en) 2015-09-13 2022-02-22 Rex Medical, L.P. Atherectomy device
US10307175B2 (en) 2016-03-26 2019-06-04 Rex Medical, L.P Atherectomy device
US10821268B2 (en) * 2016-09-14 2020-11-03 Scientia Vascular, Llc Integrated coil vascular devices
WO2018204700A1 (en) 2017-05-03 2018-11-08 Medtronic Vascular, Inc. Tissue-removing catheter with guidewire isolation liner
US11690645B2 (en) 2017-05-03 2023-07-04 Medtronic Vascular, Inc. Tissue-removing catheter
US11819236B2 (en) 2019-05-17 2023-11-21 Medtronic Vascular, Inc. Tissue-removing catheter
CN110251203A (zh) * 2019-07-26 2019-09-20 张建军 一种具有可旋转内鞘管的输尿管软镜鞘套件
US12023056B2 (en) * 2020-08-12 2024-07-02 Terumo Kabushiki Kaisha Medical device
US11696793B2 (en) 2021-03-19 2023-07-11 Crossfire Medical Inc Vascular ablation
WO2022231966A1 (en) 2021-04-27 2022-11-03 Contego Medical, Inc. Thrombus aspiration system and methods for controlling blood loss
US20240149020A1 (en) 2022-11-04 2024-05-09 Controlled Delivery Systems, Inc. Catheters for the aspiration controlled delivery of closure agents

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091880A (en) * 1975-10-17 1978-05-30 Concept Inc. Surgical wire inserter apparatus
US6440148B1 (en) * 1984-05-14 2002-08-27 Samuel Shiber Stent unclogging system with stepped spiral
US4842579B1 (en) * 1984-05-14 1995-10-31 Surgical Systems & Instr Inc Atherectomy device
US5306244A (en) * 1984-05-14 1994-04-26 Surgical Systems & Instruments, Inc. Method of guidewire insertion
US5135531A (en) * 1984-05-14 1992-08-04 Surgical Systems & Instruments, Inc. Guided atherectomy system
US5007896A (en) * 1988-12-19 1991-04-16 Surgical Systems & Instruments, Inc. Rotary-catheter for atherectomy
US5002553A (en) * 1984-05-14 1991-03-26 Surgical Systems & Instruments, Inc. Atherectomy system with a clutch
US4819634A (en) * 1984-05-14 1989-04-11 Surgical Systems & Instruments Rotary-catheter for atherectomy system
US4883458A (en) * 1987-02-24 1989-11-28 Surgical Systems & Instruments, Inc. Atherectomy system and method of using the same
US5653696A (en) 1984-05-14 1997-08-05 Surgical Systems & Instruments, Inc. Stent unclogging method
US5334211A (en) * 1984-05-14 1994-08-02 Surgical System & Instruments, Inc. Lumen tracking atherectomy system
US4732154A (en) * 1984-05-14 1988-03-22 Surgical Systems & Instruments, Inc. Rotary catheter system
US4886490A (en) * 1984-05-14 1989-12-12 Surgical Systems & Instruments, Inc. Atherectomy catheter system and method of using the same
US4894051A (en) * 1984-05-14 1990-01-16 Surgical Systems & Instruments, Inc. Atherectomy system with a biasing sleeve and method of using the same
CA1293663C (en) * 1986-01-06 1991-12-31 David Christopher Auth Transluminal microdissection device
US5116350B1 (en) 1987-03-17 1997-06-17 Cordis Corp Catheter system having distal tip for opening obstructions
US5042984A (en) * 1989-08-17 1991-08-27 Kensey Nash Corporation Catheter with working head having selectable impacting surfaces and method of using the same
US5030213A (en) 1989-08-21 1991-07-09 Rumberger William E Catheter router and method of use
US5467684A (en) 1992-03-25 1995-11-21 Sher; Arieh Rotary piston driving mechanism
US5681336A (en) * 1995-09-07 1997-10-28 Boston Scientific Corporation Therapeutic device for treating vien graft lesions
US5963276A (en) 1997-01-09 1999-10-05 Smartlight Ltd. Back projection transparency viewer with overlapping pixels
US6129734A (en) * 1997-01-21 2000-10-10 Shturman Cardiology Systems, Inc. Rotational atherectomy device with radially expandable prime mover coupling
SE9702680D0 (sv) 1997-07-11 1997-07-11 Astra Pharma Prod New formulation
US6183432B1 (en) * 1997-11-13 2001-02-06 Lumend, Inc. Guidewire and catheter with rotating and reciprocating symmetrical or asymmetrical distal tip
US20050119615A1 (en) * 2000-04-06 2005-06-02 Norborn Medical, Inc. Guidewire for crossing occlusions or stenoses
AU6279299A (en) * 1998-10-02 2000-04-26 Stereotaxis, Inc. Magnetically navigable and/or controllable device for removing material from body lumens and cavities
US6758851B2 (en) * 1999-02-02 2004-07-06 Samuel Shiber Vessel cleaner
US7316697B2 (en) * 1999-02-02 2008-01-08 Samuel Shiber Vessel cleaning system with asymmetrical auto retracting agitator
US6482215B1 (en) * 1999-02-02 2002-11-19 Samuel Shiber Adjustable vessel cleaner and method
US6818002B2 (en) * 1999-02-02 2004-11-16 Samuel Shiber Vessel cleaner and barrier
US6143009A (en) * 1999-02-02 2000-11-07 Shiber; Samuel Flexible-agitator system and method
US6663613B1 (en) * 2000-01-25 2003-12-16 Bacchus Vascular, Inc. System and methods for clot dissolution
WO2001054595A1 (en) * 2000-01-31 2001-08-02 Rex Medical, Lp Atherectomy device and methods
US7344546B2 (en) * 2000-04-05 2008-03-18 Pathway Medical Technologies Intralumenal material removal using a cutting device for differential cutting
CA2403925C (en) * 2000-04-05 2008-09-16 Stx Medical, Inc. Intralumenal material removal systems and methods
US6416523B1 (en) * 2000-10-03 2002-07-09 Scimed Life Systems, Inc. Method and apparatus for creating channels through vascular total occlusions
US6500186B2 (en) * 2001-04-17 2002-12-31 Scimed Life Systems, Inc. In-stent ablative tool
US20040102719A1 (en) 2002-11-22 2004-05-27 Velocimed, L.L.C. Guide wire control catheters for crossing occlusions and related methods of use
GB2426456B (en) * 2005-05-26 2010-10-27 Leonid Shturman Rotational device with eccentric abrasive element and method of use
GB2426458A (en) * 2005-05-26 2006-11-29 Leonid Shturman Atherectomy device
US8007506B2 (en) * 2006-06-30 2011-08-30 Atheromed, Inc. Atherectomy devices and methods
US20090018566A1 (en) * 2006-06-30 2009-01-15 Artheromed, Inc. Atherectomy devices, systems, and methods
GB0613980D0 (en) * 2006-07-13 2006-08-23 Shturman Leonid Rotational Atherectomy Device with Fluid Inflatable Elements supported by Fluid Bearings
US8597313B2 (en) * 2007-06-11 2013-12-03 Cardiovascular Systems, Inc. Eccentric abrading head for high-speed rotational atherectomy devices
US8236016B2 (en) * 2007-10-22 2012-08-07 Atheromed, Inc. Atherectomy devices and methods
US8551128B2 (en) * 2007-12-06 2013-10-08 Cardiovascular Systems, Inc. Rotational atherectomy device with pre-curved drive shaft
US9101387B2 (en) * 2008-06-05 2015-08-11 Cardiovascular Systems, Inc. Directional rotational atherectomy device with offset spinning abrasive element
US8632557B2 (en) * 2009-05-12 2014-01-21 Cardiovascular Systems, Inc. Rotational atherectomy device and method to improve abrading efficiency
US20130103046A1 (en) * 2010-05-04 2013-04-25 Samuel Shiber Rotary catheter for removing obstructions from bodily vessels
WO2013025697A1 (en) * 2011-08-17 2013-02-21 Samuel Shiber Adaptive rotary catheter for opening obstructed bodily vessels
US20150094733A1 (en) * 2010-05-04 2015-04-02 Samuel Shiber Rotary catheter drive unit containing seal-sets
US9907567B2 (en) * 2010-05-04 2018-03-06 Samuel Shiber Mechanical — pharmaceutical system for opening obstructed bodily vessels
US20120172905A1 (en) * 2010-12-30 2012-07-05 Kimberly-Clark, Inc. Tissue Removal Apparatus and Method of Manufacturing Same
CN103957825B (zh) * 2011-10-13 2018-12-07 阿瑟罗迈德公司 粥样斑块切除装置、系统和方法

Also Published As

Publication number Publication date
EP2744424A1 (en) 2014-06-25
ES2657019T3 (es) 2018-03-01
US9700347B2 (en) 2017-07-11
EP2744424A4 (en) 2015-04-22
EP2744424B1 (en) 2017-11-08
US20140200599A1 (en) 2014-07-17
WO2013025697A1 (en) 2013-02-21

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