DK2717692T3 - Tetrahydrocannabinol-11-syrer til anvendelse til behandling af fibrotiske sygdomme - Google Patents

Tetrahydrocannabinol-11-syrer til anvendelse til behandling af fibrotiske sygdomme Download PDF

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Publication number
DK2717692T3
DK2717692T3 DK12796691T DK12796691T DK2717692T3 DK 2717692 T3 DK2717692 T3 DK 2717692T3 DK 12796691 T DK12796691 T DK 12796691T DK 12796691 T DK12796691 T DK 12796691T DK 2717692 T3 DK2717692 T3 DK 2717692T3
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DK
Denmark
Prior art keywords
tetrahydrocannabinol
treatment
acids used
fibrotic diseases
fibrotic
Prior art date
Application number
DK12796691T
Other languages
English (en)
Inventor
Robert B Zurier
Enrico Selvi
Original Assignee
Corbus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corbus Pharmaceuticals Inc filed Critical Corbus Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2717692T3 publication Critical patent/DK2717692T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK12796691T 2011-06-04 2012-06-01 Tetrahydrocannabinol-11-syrer til anvendelse til behandling af fibrotiske sygdomme DK2717692T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161493435P 2011-06-04 2011-06-04
US13/485,044 US20120309820A1 (en) 2011-06-04 2012-05-31 Methods of treating fibrotic diseases using tetrahydrocannabinol-11-oic acids
PCT/US2012/040380 WO2012170290A1 (en) 2011-06-04 2012-06-01 Methods of treating fibrotic diseases using tetrahydrocannabinol-11-oic acids

Publications (1)

Publication Number Publication Date
DK2717692T3 true DK2717692T3 (da) 2019-11-11

Family

ID=47262154

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12796691T DK2717692T3 (da) 2011-06-04 2012-06-01 Tetrahydrocannabinol-11-syrer til anvendelse til behandling af fibrotiske sygdomme

Country Status (8)

Country Link
US (3) US20120309820A1 (da)
EP (2) EP2717692B1 (da)
DK (1) DK2717692T3 (da)
ES (1) ES2753639T3 (da)
HU (1) HUE047419T2 (da)
PL (1) PL2717692T3 (da)
PT (1) PT2717692T (da)
WO (1) WO2012170290A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2956133A4 (en) * 2013-02-12 2016-12-21 Corbus Pharmaceuticals Inc ULTRAPURIC TETRAHYDROCANNABINOL-11-OIC ACIDS
JP6307290B2 (ja) * 2013-03-06 2018-04-04 東京応化工業株式会社 レジスト組成物、レジストパターン形成方法
WO2015200049A1 (en) 2014-06-26 2015-12-30 Island Breeze Systems Ca, Llc Mdi related products and methods of use
EP3399974A4 (en) * 2016-01-08 2019-09-04 Colonaryconcepts LLC FOOD-BASED DELIVERY OF CANNABINOIDS
US20190060300A1 (en) * 2016-03-04 2019-02-28 Sharon Anavi-Goffer Self-Emulsifying Compositions of CB2 Receptor Modulators
CN109715152A (zh) * 2016-04-29 2019-05-03 柯巴斯医药有限公司 医治感染的方法
US20210284621A1 (en) * 2018-05-31 2021-09-16 Corbus Pharmaceuticals, Inc. Cannabinoids and uses thereof
US20210267959A1 (en) * 2018-07-17 2021-09-02 The Regents Of The University Of California Methods of treating renal disease
GB201905371D0 (en) 2019-04-16 2019-05-29 Mission Therapeutics Ltd Novel compounds
GB201905375D0 (en) 2019-04-16 2019-05-29 Mission Therapeutics Ltd Novel compounds
GB201912674D0 (en) 2019-09-04 2019-10-16 Mission Therapeutics Ltd Novel compounds
JP2023520727A (ja) 2020-04-08 2023-05-18 ミッション セラピューティクス リミティド Usp30阻害剤として活性を有するn-シアノピロリジン
EP4157834A1 (en) 2020-05-28 2023-04-05 Mission Therapeutics Limited N-(1-cyano-pyrrolidin-3-yl)-5-(3-(trifluoromethyl)phenyl)oxazole-2-carboxamide derivatives and the corresponding oxadiazole derivatives as usp30 inhibitors for the treatment of mitochondrial dysfunction
CN115698001A (zh) 2020-06-04 2023-02-03 特殊治疗有限公司 具有作为usp30抑制剂活性的n-氰基吡咯烷类化合物
WO2021249909A1 (en) 2020-06-08 2021-12-16 Mission Therapeutics Limited 1-(5-(2-cyanopyridin-4-yl)oxazole-2-carbonyl)-4-methylhexahydropyrrolo[3,4-b]pyr role-5(1h)-carbonitrile as usp30 inhibitor for use in the treatment of mitochondrial dysfunction, cancer and fibrosis
GB202016800D0 (en) 2020-10-22 2020-12-09 Mission Therapeutics Ltd Novel compounds
WO2023099561A1 (en) 2021-12-01 2023-06-08 Mission Therapeutics Limited Substituted n-cyanopyrrolidines with activity as usp30 inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7507767B2 (en) * 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
AU2003303376A1 (en) * 2002-12-19 2004-07-22 University Of Massachusetts Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators
US8058227B2 (en) * 2006-10-03 2011-11-15 Medical University Of South Carolina Method of treating fibrosis in a subject in need thereof comprising administering a composition comprising a CSD
US8877188B2 (en) * 2010-05-04 2014-11-04 The Brigham And Women's Hospital, Inc. Detection and treatment of non-dermal fibrosis

Also Published As

Publication number Publication date
EP2717692B1 (en) 2019-08-07
EP2717692A4 (en) 2015-02-18
ES2753639T3 (es) 2020-04-13
US20120309820A1 (en) 2012-12-06
WO2012170290A1 (en) 2012-12-13
US20160367518A1 (en) 2016-12-22
HUE047419T2 (hu) 2020-04-28
EP3620211A1 (en) 2020-03-11
PL2717692T3 (pl) 2020-06-15
PT2717692T (pt) 2019-11-18
EP2717692A1 (en) 2014-04-16
US20180116999A1 (en) 2018-05-03

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