DK258988A - Individuelle isomere af endo-bicyclo(2.21)heptyladenosin - Google Patents

Individuelle isomere af endo-bicyclo(2.21)heptyladenosin

Info

Publication number
DK258988A
DK258988A DK258988A DK258988A DK258988A DK 258988 A DK258988 A DK 258988A DK 258988 A DK258988 A DK 258988A DK 258988 A DK258988 A DK 258988A DK 258988 A DK258988 A DK 258988A
Authority
DK
Denmark
Prior art keywords
heptyladenosine
endo
bicyclo
individual isomers
isomers
Prior art date
Application number
DK258988A
Other languages
English (en)
Other versions
DK258988D0 (da
Inventor
Bharat Kalidas Trivedi
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK258988D0 publication Critical patent/DK258988D0/da
Publication of DK258988A publication Critical patent/DK258988A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK258988A 1987-05-13 1988-05-11 Individuelle isomere af endo-bicyclo(2.21)heptyladenosin DK258988A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/049,178 US4837207A (en) 1987-05-13 1987-05-13 Diastereoisomers of n6 -endo-bicyclo[2.2.1]heptyladenosine as antihypertensives with selective action

Publications (2)

Publication Number Publication Date
DK258988D0 DK258988D0 (da) 1988-05-11
DK258988A true DK258988A (da) 1988-11-14

Family

ID=21958440

Family Applications (1)

Application Number Title Priority Date Filing Date
DK258988A DK258988A (da) 1987-05-13 1988-05-11 Individuelle isomere af endo-bicyclo(2.21)heptyladenosin

Country Status (11)

Country Link
US (1) US4837207A (da)
EP (1) EP0291051A3 (da)
JP (1) JPS63287794A (da)
KR (1) KR880013966A (da)
AU (1) AU1530888A (da)
DK (1) DK258988A (da)
FI (1) FI882210A (da)
NZ (1) NZ224580A (da)
PH (1) PH25482A (da)
PT (1) PT87462B (da)
ZA (1) ZA882919B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992535A (en) * 1988-10-26 1991-02-12 G. D. Searle & Co. Methods of making novel R and S diastereomers of N6 -[(2-hydroxypropyl)aryl]adenosines
JPH0725785B2 (ja) * 1989-01-11 1995-03-22 日本臓器製薬株式会社 アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
US5055569A (en) * 1989-10-19 1991-10-08 G. D. Searle & Co. N-(6)-substituted adenosine compounds
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
US5426101A (en) * 1992-09-30 1995-06-20 Merrell Dow Pharmaceuticals Inc. 2-substituted adenosines with A-2 receptor affinity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7203984A (da) * 1971-04-10 1972-10-12
DE2230160A1 (de) * 1972-06-21 1974-01-31 Merck Patent Gmbh Adenosinderivat
US4501735A (en) * 1983-12-05 1985-02-26 Warner-Lambert Company N6-(1- and 2-benzocycloalkyl) adenosines
US4714697A (en) * 1985-09-09 1987-12-22 Warner Lambert Company N6 -bicycloadenosines and methods of use
AU579412B2 (en) * 1984-10-26 1988-11-24 Warner-Lambert Company N` - substituted adenosines
CA1254888A (en) * 1984-10-26 1989-05-30 Bharat Trivedi N.sup.6-bicycloadenosines

Also Published As

Publication number Publication date
DK258988D0 (da) 1988-05-11
EP0291051A2 (en) 1988-11-17
JPS63287794A (ja) 1988-11-24
PT87462B (pt) 1992-08-31
US4837207A (en) 1989-06-06
EP0291051A3 (en) 1990-03-14
ZA882919B (en) 1989-12-27
KR880013966A (ko) 1988-12-22
PT87462A (pt) 1989-05-31
AU1530888A (en) 1988-11-17
FI882210A0 (fi) 1988-05-11
NZ224580A (en) 1990-12-21
PH25482A (en) 1991-07-01
FI882210A (fi) 1988-11-14

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment