DK2482884T3 - Lægemiddelfremføringsanordning og drivdel til en lægemiddelfremføringsanordning - Google Patents

Lægemiddelfremføringsanordning og drivdel til en lægemiddelfremføringsanordning Download PDF

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Publication number
DK2482884T3
DK2482884T3 DK10757779.3T DK10757779T DK2482884T3 DK 2482884 T3 DK2482884 T3 DK 2482884T3 DK 10757779 T DK10757779 T DK 10757779T DK 2482884 T3 DK2482884 T3 DK 2482884T3
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Denmark
Prior art keywords
dose
drive member
drug delivery
delivery device
piston rod
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Application number
DK10757779.3T
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English (en)
Inventor
David Plumptre
Catherine Anne Macdonald
Christopher Jones
Garen Kouyoumjian
Andrew Mark Lindsay
Robert Veasey
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Sanofi Aventis Deutschland
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Publication of DK2482884T3 publication Critical patent/DK2482884T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (14)

1. Drivdel til at drive en stempelstang i en lægemiddelfremføringsanordning, 5 hvilken drivdel (1) har en længdegående akse (100) med en distal retning (103) og en proksimal retning (104), hvor drivdelen (1) er konfigureret til at blive drevet i en rotationsbevægelse omkring den længdegående akse (100) ved hjælp af en aktueringsdel, hvor drivdelen (1) omfatter et spor 10 (12) med en kontaktflade (120) til overførsel af en drivende belastning fra aktueringsdelen til drivdelen (1), hvor sporet (12) omfatter både sektioner, der går i den distale retning (103), og sektioner, der går i den proksimale retning (104) af drivdelen (1), der er kendetegnet ved, at 15 drivdelen omfatter et påvirkningsspor (14) med en kontaktflade (140) til overførsel af en belastning fra en komponent af påvirkningsmidlet til drivdelen (1) til påvirkning af drivdelen (1) mod en rotation omkring den længdegående akse (100) . 20
2. Drivdel ifølge krav 1, hvor sporet (12) omfatter mindst én dosisindstillingssektion (122) og mindst én dosisdispenseringssektion (125), hvor aktueringsdelen i en samlet form af en 25 lægemiddelfremføringsanordning (4) kommer i kontakt med kontaktfladen (120) på dosisindstillingssektionen (122) til indstilling af en dosis og på dosisdispenseringssektionen (125) til dispensering af en dosis.
3. Drivdel ifølge krav 1, hvor påvirkningssporet (14) omfatter en første omdirigeringssektion (142), der skråner mod den længdegående akse (100) .
4. Drivdel ifølge krav 3, hvor påvirkningssporet (14) omfatter en anden omdirigeringssektion (143), der skråner mod den længdegående akse (100) på en måde modsat den første omdirigeringssektion (142) .
5. Drivdel ifølge krav 4, hvor den første (142) og anden omdirigeringssektion (143) 5 grænser op til hinanden til derved frembringelse af en forsænkning (144) i påvirkningssporet (14).
6.
Drivdel ifølge et hvilket som helst af kravene 1 til 5, der omfatter et koblingsmiddel, der er konfigureret til at 10 koble en stempelstang (5) til drivdelen (1), således at en relativ translationsbevægelse af drivdelen (1) og stempelstangen (5) muliggøres, og en relativt rotationsbevægelse forhindres. 15 7. Lægemiddelfremføringsanordning, der omfatter en drivdel (1) ifølge et hvilket som helst af ovennævnte krav og en aktueringsdel til at drive drivdelen (1) , hvilken anordning (4) er konfigureret til at dispensere en dosis af et 20 lægemiddel i en dosisdispenseringsoperation samt er konfigureret til at blive klargjort til en efterfølgende dosisdispenseringsoperation i en dosisindstillingsoperation.
8. Lægemiddelfremføringsanordning ifølge krav 7, der 25 omfatter et påvirkningsmiddel, der er konfigureret til at påvirke drivdelen (1) ved den ene eller begge af afslutningen af en dosisindstillingsoperation og en dosisdispenseringsoperation mod en rotation omkring den længdegående akse. 30
9. Lægemiddelfremføringsanordning ifølge et hvilket som helst af kravene 7 eller 8, hvor ved afslutningen af en dosisindstillingsoperation påvirkningen, der udøves af påvirkningsmidlet, resulterer i en 35 rotation af drivdelen (1) mod en position i forhold til aktueringsdelen, således at en efterfølgende dosisdispenseringsoperation muliggøres.
10.
Lægemiddelfremføringsanordning ifølge et hvilket som helst af kravene 7 til 9, der omfatter en stempelstang (5) , der er konfigureret til at blive drevet af drivdelen (1) i en 5 dosisdispenseringsoperation, hvor en relativ rotationsbevægelse mellem stempelstangen og drivdelen (1) forhindres, og en relativ aksial bevægelse muliggøres. 10 11. Lægemiddelfremføringsanordning ifølge krav 10, hvor ved afslutningen af en dosisdispenseringsoperation en vridning, der udøves af påvirkningsmidlet, resulterer i en rotation af drivdelen (1), således at stempelstangen (5) bevæges i den proksimale retning (104) til derved muliggørelse 15 af løsnen af en spuns (444) i en patron (442) mod den proksimale retning (104) af lægemiddelfremføringsanordningen (4) .
12.
Lægemiddelfremføringsanordning ifølge et hvilket som 20 helst af kravene 7 til 11, der omfatter en komponent med gevind, der er fastgjort til et hus på lægemiddelfremføringsanordningen, hvor komponenten med gevind er i gevindindgreb med stempelstangen (5).
25 13. Lægemiddelfremføringsanordning ifølge et hvilket som helst af kravene 7 til 12, der omfatter en dosisdel (46) , der kan betjenes af en bruger, hvilken dosisdel (46) fungerer som aktueringsdelen til drivning af drivdelen (1). 30 14. Lægemiddelfremføringsanordning ifølge krav 13, hvor dosisdelen (46) er konfigureret til at blive trukket til indstilling af en dosis og til at blive skubbet til dispensering af den indstillede dosis.
DK10757779.3T 2009-09-30 2010-09-29 Lægemiddelfremføringsanordning og drivdel til en lægemiddelfremføringsanordning DK2482884T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09171738 2009-09-30
PCT/EP2010/064395 WO2011039205A2 (en) 2009-09-30 2010-09-29 Drug delivery device and drive member for a drug delivery device

Publications (1)

Publication Number Publication Date
DK2482884T3 true DK2482884T3 (da) 2016-02-08

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Country Link
US (1) US9533107B2 (da)
EP (1) EP2482884B1 (da)
JP (1) JP5768051B2 (da)
CN (1) CN102548600B (da)
AU (1) AU2010303049B2 (da)
BR (1) BR112012007120A2 (da)
CA (1) CA2773011A1 (da)
DK (1) DK2482884T3 (da)
HK (1) HK1168819A1 (da)
IL (1) IL218830A0 (da)
WO (1) WO2011039205A2 (da)

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Publication number Publication date
EP2482884A2 (en) 2012-08-08
IL218830A0 (en) 2012-06-28
US9533107B2 (en) 2017-01-03
AU2010303049B2 (en) 2014-11-20
CN102548600B (zh) 2014-06-25
AU2010303049A1 (en) 2012-04-19
JP2013506444A (ja) 2013-02-28
JP5768051B2 (ja) 2015-08-26
WO2011039205A2 (en) 2011-04-07
BR112012007120A2 (pt) 2016-07-12
CA2773011A1 (en) 2011-04-07
WO2011039205A3 (en) 2011-05-26
EP2482884B1 (en) 2015-11-04
HK1168819A1 (zh) 2013-01-11
US20120283655A1 (en) 2012-11-08
CN102548600A (zh) 2012-07-04

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