DK2367001T3 - Biospecifikke bindingsreaktanter markeret med nye luminescerende lanthanidchelater og deres anvendelse - Google Patents

Biospecifikke bindingsreaktanter markeret med nye luminescerende lanthanidchelater og deres anvendelse

Info

Publication number
DK2367001T3
DK2367001T3 DK10183588.2T DK10183588T DK2367001T3 DK 2367001 T3 DK2367001 T3 DK 2367001T3 DK 10183588 T DK10183588 T DK 10183588T DK 2367001 T3 DK2367001 T3 DK 2367001T3
Authority
DK
Denmark
Prior art keywords
luminescing
reactants
marked
new
lanthanide chelates
Prior art date
Application number
DK10183588.2T
Other languages
Danish (da)
English (en)
Inventor
Harri Takalo
Jaana Rosenberg
Original Assignee
Dhr Finland Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dhr Finland Oy filed Critical Dhr Finland Oy
Application granted granted Critical
Publication of DK2367001T3 publication Critical patent/DK2367001T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/40—Rare earth chelates
DK10183588.2T 2003-02-13 2004-02-03 Biospecifikke bindingsreaktanter markeret med nye luminescerende lanthanidchelater og deres anvendelse DK2367001T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/365,637 US7018851B2 (en) 2003-02-13 2003-02-13 Biospecific binding reactants labeled with new luminescent lanthanide chelates and their use
EP04396007A EP1447666B8 (en) 2003-02-13 2004-02-03 Biospecific binding reactants labeled with new luminescent lanthanide chelates and their use

Publications (1)

Publication Number Publication Date
DK2367001T3 true DK2367001T3 (da) 2014-10-20

Family

ID=32681717

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10183588.2T DK2367001T3 (da) 2003-02-13 2004-02-03 Biospecifikke bindingsreaktanter markeret med nye luminescerende lanthanidchelater og deres anvendelse

Country Status (4)

Country Link
US (1) US7018851B2 (US20040166585A1-20040826-C00003.png)
EP (2) EP2367001B1 (US20040166585A1-20040826-C00003.png)
DK (1) DK2367001T3 (US20040166585A1-20040826-C00003.png)
ES (2) ES2391952T3 (US20040166585A1-20040826-C00003.png)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1658282B1 (en) * 2003-08-29 2010-10-27 Wallac Oy Novel chelating agents and chelates and their use
EP1848466A4 (en) * 2005-01-31 2012-11-21 Yeda Res & Dev MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS
EP2052252B1 (en) 2006-08-18 2010-11-10 Abacus Diagnostica OY Luminescent lanthanide labelling reagents and their use
WO2008025886A1 (en) * 2006-09-01 2008-03-06 Wallac Oy Metal chelates and chelating agents containing triazolyl subunits
JP5606435B2 (ja) * 2008-07-16 2014-10-15 ラジオメーター・メディカル・アー・ペー・エス トロンビン基質およびサンプル中の生体活性トロンビンのレベルを測定するためのアッセイ
US9944657B2 (en) * 2011-08-19 2018-04-17 Radiometer Turku Oy Luminescent lanthanide chelates having three chromophores an their use
EP2753674B1 (en) * 2011-08-19 2016-02-10 DHR Finland Oy Luminescent lanthanide chelates having three chromophores and their use
US9518186B2 (en) 2011-12-22 2016-12-13 Radiometer Turku Oy Luminescent lanthanide chelates with enhanced excitation properties
US20150307774A1 (en) 2012-09-24 2015-10-29 Qi Wang Chelates, chelating agents, conjugates derived thereof and their use
WO2014147288A1 (en) 2013-01-31 2014-09-25 Kaivogen Oy Luminescent triazacyclononane-based lanthanide chelate complexes as labelling reagents
EP3768665A1 (en) 2018-03-20 2021-01-27 Radiometer Turku Oy Luminescent lanthanide chelates and their use
FI128833B (en) 2019-12-09 2021-01-15 Abacus Diagnostica Oy Luminescent lanthanide (III) chelates
CN113238038B (zh) * 2021-05-11 2021-12-17 图凌(杭州)生物医药有限公司 用于免疫组织化学检测的抗体稀释液及其制备方法和应用

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US4859777A (en) 1981-07-01 1989-08-22 Eastman Kodak Company Terpyridine chelating agents
US4670572A (en) 1981-07-01 1987-06-02 Eastman Kodak Company Phenolic fluorescent labels
US4801722A (en) 1981-07-01 1989-01-31 Eastman Kodak Company Coumarin chelates
US4794191A (en) 1981-07-01 1988-12-27 Eastman Kodak Company Fluorescent chelates
FR2541282B1 (fr) 1983-02-23 1985-10-11 Roussel Uclaf Nouveaux derives de l'hydroxylamine, leur procede de preparation et leur application comme facteurs de croissance des vegetaux
GB8420521D0 (en) 1984-08-13 1984-09-19 Hsc Res Dev Corp Fluorescent label
FR2570703B1 (fr) 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4761481A (en) 1985-03-18 1988-08-02 Baxter Travenol Laboratories, Inc. Substituted pyridine derivatives
SE8502573D0 (sv) 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
US5032677A (en) 1987-11-06 1991-07-16 Baxter International Inc. Fluorescent poly(arylpyridine) rare earth chelates
US5055578A (en) 1987-11-06 1991-10-08 Baxter Diagnostics Inc. Fluorescent poly(arylpyridine) rare earth chelates
US4801772A (en) * 1988-03-02 1989-01-31 Westinghouse Electric Corp Current limiting circuit interrupter with insulating wedge
CA1340527C (en) 1988-05-31 1999-05-04 Lidia Vallarino Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
US5202423A (en) 1988-07-08 1993-04-13 Wallac Oy Terpyridine derivatives
US4920192A (en) * 1989-01-31 1990-04-24 Atlantic Richfield Company Polyurethane quasi prepolymer for proppant consolidation
US5216134A (en) 1989-10-23 1993-06-01 Wallac Oy Spectrofluorometric method and compounds that are of value for the method
EP0493745A1 (en) 1990-12-21 1992-07-08 Dojindo Laboratories Fluorescent compound, complex, reagent, and specific binding assay employing said reagent
FR2680787B1 (fr) 1991-08-30 1994-11-04 Cis Bio Int Complexes macrocycliques de terres rares et leur utilisation pour reduire les interferences dans un dosage par fluorescence.
ES2133312T3 (es) 1991-12-05 1999-09-16 Wallac Oy Quelatos de lantanidos luminiscentes.
US5457186A (en) 1993-10-13 1995-10-10 Wallac Oy Luminescent lanthanide chelates with decreased non-radiative energy loss
US5859215A (en) 1995-10-25 1999-01-12 Wallac Oy Biospecific binding reactants labelled with luminescent lanthanide chelates and their use
US6080839A (en) 1998-06-25 2000-06-27 Wallac Oy Labeling reactants and their use
DE60141871D1 (de) 2000-05-05 2010-06-02 Wallac Oy Oligonukleotidmarkierungsstoffe und ihre Verwendung

Also Published As

Publication number Publication date
US20040166585A1 (en) 2004-08-26
EP2367001B1 (en) 2014-07-30
EP1447666A3 (en) 2004-09-29
EP1447666A2 (en) 2004-08-18
ES2509218T3 (es) 2014-10-17
EP1447666B1 (en) 2012-07-25
US7018851B2 (en) 2006-03-28
EP1447666B8 (en) 2012-09-12
EP2367001A1 (en) 2011-09-21
ES2391952T3 (es) 2012-12-03

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