DK2328622T3 - Radiolabelled annexins - Google Patents
Radiolabelled annexins Download PDFInfo
- Publication number
- DK2328622T3 DK2328622T3 DK09810266.8T DK09810266T DK2328622T3 DK 2328622 T3 DK2328622 T3 DK 2328622T3 DK 09810266 T DK09810266 T DK 09810266T DK 2328622 T3 DK2328622 T3 DK 2328622T3
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- DK
- Denmark
- Prior art keywords
- annexin
- subject
- radiolabelled
- leu
- ala
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
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- A61K51/087—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being an annexin, e.g. annexin V
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
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- A—HUMAN NECESSITIES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K49/00—Preparations for testing in vivo
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical & Material Sciences (AREA)
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- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08162959 | 2008-08-26 | ||
| PCT/NL2009/050513 WO2010024673A1 (en) | 2008-08-26 | 2009-08-26 | Radiolabeled annexins |
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| DK2328622T3 true DK2328622T3 (en) | 2015-02-02 |
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| DK09810266.8T DK2328622T3 (en) | 2008-08-26 | 2009-08-26 | Radiolabelled annexins |
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| JP (1) | JP5801196B2 (enExample) |
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| CA (1) | CA2735214C (enExample) |
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| ES (1) | ES2530228T3 (enExample) |
| NZ (1) | NZ591388A (enExample) |
| WO (1) | WO2010024673A1 (enExample) |
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| GB0914446D0 (en) * | 2009-08-18 | 2009-09-30 | King S College London | Bioconjugates and their uses in imaging |
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| CN1265572A (zh) | 1997-04-30 | 2000-09-06 | 莱兰斯坦福初级大学评议会 | 活体内造影细胞死亡的方法 |
| US6323313B1 (en) * | 1999-06-01 | 2001-11-27 | The University Of Washington | Annexin derivative with endogenous chelation sites |
| US7635676B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaccuticals, Inc. | Modified annexin proteins and methods for their use in organ transplantation |
| AU2003903504A0 (en) * | 2003-07-08 | 2003-07-24 | Johnson, Daniel | Improvements in sensor chips |
| CA2559167A1 (en) | 2004-03-11 | 2005-09-22 | Alavita, Inc. | Modified annexin proteins and methods for preventing thrombosis |
| US7511016B2 (en) | 2004-07-07 | 2009-03-31 | Mosamedix B.V. | Annexins, derivatives thereof, and annexin-cys variants, as well as therapeutic and diagnostic uses thereof |
| JP2006316004A (ja) | 2005-05-13 | 2006-11-24 | Kanazawa Univ | アポトーシスのイメージング剤 |
| NZ569078A (en) | 2005-12-12 | 2012-01-12 | Mosamedix Bv | Annexin derivatives suitable for pretargeting in therapy and diagnosis |
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2009
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- 2009-08-26 EP EP09810266.8A patent/EP2328622B1/en not_active Not-in-force
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- 2009-08-26 AU AU2009286244A patent/AU2009286244B2/en not_active Ceased
- 2009-08-26 US US13/060,667 patent/US8747808B2/en not_active Expired - Fee Related
- 2009-08-26 JP JP2011524925A patent/JP5801196B2/ja not_active Expired - Fee Related
- 2009-08-26 CA CA2735214A patent/CA2735214C/en not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2328622A1 (en) | 2011-06-08 |
| US20110251486A1 (en) | 2011-10-13 |
| WO2010024673A1 (en) | 2010-03-04 |
| JP5801196B2 (ja) | 2015-10-28 |
| EP2328622B1 (en) | 2014-12-17 |
| CA2735214A1 (en) | 2010-03-04 |
| AU2009286244B2 (en) | 2014-08-14 |
| AU2009286244A1 (en) | 2010-03-04 |
| ES2530228T3 (es) | 2015-02-27 |
| NZ591388A (en) | 2012-06-29 |
| CA2735214C (en) | 2020-02-18 |
| US8747808B2 (en) | 2014-06-10 |
| JP2012501322A (ja) | 2012-01-19 |
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