DK2274005T3 - Behandling af tumorsygdomme med angiotensin konverterende enzym 2 (ACE2) - Google Patents

Behandling af tumorsygdomme med angiotensin konverterende enzym 2 (ACE2)

Info

Publication number
DK2274005T3
DK2274005T3 DK09730771.4T DK09730771T DK2274005T3 DK 2274005 T3 DK2274005 T3 DK 2274005T3 DK 09730771 T DK09730771 T DK 09730771T DK 2274005 T3 DK2274005 T3 DK 2274005T3
Authority
DK
Denmark
Prior art keywords
ace2
treatment
converting enzyme
angiotensin converting
tumor diseases
Prior art date
Application number
DK09730771.4T
Other languages
Danish (da)
English (en)
Inventor
Evelyne Janzek-Hawlat
Hans Loibner
Manfred Schuster
Bernhard Peball
Original Assignee
Apeiron Biologics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apeiron Biologics Ag filed Critical Apeiron Biologics Ag
Application granted granted Critical
Publication of DK2274005T3 publication Critical patent/DK2274005T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813Exopeptidases (3.4.11. to 3.4.19)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/17Metallocarboxypeptidases (3.4.17)
    • C12Y304/17023Angiotensin-converting enzyme 2 (3.4.17.23)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK09730771.4T 2008-04-09 2009-04-07 Behandling af tumorsygdomme med angiotensin konverterende enzym 2 (ACE2) DK2274005T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0056608A AT506632A1 (de) 2008-04-09 2008-04-09 Behandlung von tumorerkrankungen
PCT/AT2009/000136 WO2009124330A2 (de) 2008-04-09 2009-04-07 Behandlung von tumorerkrankungen

Publications (1)

Publication Number Publication Date
DK2274005T3 true DK2274005T3 (da) 2013-08-19

Family

ID=41130316

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09730771.4T DK2274005T3 (da) 2008-04-09 2009-04-07 Behandling af tumorsygdomme med angiotensin konverterende enzym 2 (ACE2)

Country Status (12)

Country Link
US (1) US8946162B2 (OSRAM)
EP (2) EP2274005B1 (OSRAM)
JP (1) JP5650639B2 (OSRAM)
AT (1) AT506632A1 (OSRAM)
AU (1) AU2009235931B2 (OSRAM)
CA (1) CA2720616C (OSRAM)
DK (1) DK2274005T3 (OSRAM)
ES (1) ES2425308T3 (OSRAM)
NZ (1) NZ588435A (OSRAM)
PL (1) PL2274005T3 (OSRAM)
PT (1) PT2274005E (OSRAM)
WO (1) WO2009124330A2 (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT505262A1 (de) * 2007-06-12 2008-12-15 Apeiron Biolog Forschungs Und Rekombinantes ace2 polypeptid
CN104395750B (zh) * 2012-06-06 2017-06-30 阿托奎特诊断有限公司 测量血液样品中蛋白水解级联的肽降解产物的方法
US8557958B1 (en) 2012-06-18 2013-10-15 Tarix Pharmaceuticals Ltd. Compositions and methods for treatment of diabetes
US8633158B1 (en) 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
CA2897251C (en) * 2013-01-14 2022-07-12 Apeiron Biologics Ag Modified ace2 polypeptides
PL3079684T3 (pl) * 2013-12-11 2020-06-01 Alterras Therapeutics Gmbh Kompozycje i sposoby do leczenia chorób związanych z układem renina-angiotensyna
US9333233B2 (en) 2014-02-25 2016-05-10 Tarix Pharmaceuticals Ltd. Methods and compositions for the delayed treatment of stroke
US20200188473A1 (en) * 2017-05-02 2020-06-18 Beth Israel Deaconess Medical Center, Inc. Combination therapy for cancer
EP3717077A1 (en) * 2017-11-29 2020-10-07 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft Methods for modulating pigmentation by angiotensin-converting enzyme 2 modulation
WO2021190980A1 (en) 2020-03-22 2021-09-30 Quadrucept Bio Limited Multimers for viral strain evolution
US20230181759A1 (en) * 2020-04-01 2023-06-15 Washington University Compositions for treatment of viral respiratory infections and methods of use thereof
CN112626099A (zh) * 2020-09-29 2021-04-09 清华大学 使用原核细胞发酵表达血管紧张素转化酶2的方法
WO2022184659A1 (en) 2021-03-01 2022-09-09 Quadrucept Bio Limited Antibody domains & multimers
WO2023102156A1 (en) 2021-12-03 2023-06-08 Wisconsin Alumni Research Foundation Mutant ace2 proteins and methods of using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194556B1 (en) 1997-12-11 2001-02-27 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor
US6610497B1 (en) 1997-12-11 2003-08-26 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor
US6989363B1 (en) * 1997-12-11 2006-01-24 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor
WO2003072059A2 (en) * 2002-02-27 2003-09-04 Wake Forest University Angiotensin-(1-7) and angiotensin-(1-7) agonists for inhibition of cancer cell growth
EP2047867B1 (en) * 2002-06-19 2013-05-22 Apeiron Biologics AG ACE2 activation for treatment of heart, lung and kidney disease and hypertension
EP1374907A3 (en) 2002-06-24 2004-01-07 Ghanem Elias c/o Institut Jules Bordet Ghanem Drug transport and delivery system
EP1723962A1 (en) * 2005-05-19 2006-11-22 IMBA-Institut für Molekulare Biotechnologie GmbH Use of inhibitors of the renin-angiotensin system for the treatment of lung injuries
AT505262A1 (de) * 2007-06-12 2008-12-15 Apeiron Biolog Forschungs Und Rekombinantes ace2 polypeptid

Also Published As

Publication number Publication date
AU2009235931A1 (en) 2009-10-15
ES2425308T3 (es) 2013-10-14
AU2009235931B2 (en) 2015-07-23
US20110033524A1 (en) 2011-02-10
EP2274005B1 (de) 2013-05-29
AT506632A1 (de) 2009-10-15
WO2009124330A3 (de) 2009-12-10
JP5650639B2 (ja) 2015-01-07
CA2720616C (en) 2016-08-09
CA2720616A1 (en) 2009-10-15
WO2009124330A2 (de) 2009-10-15
NZ588435A (en) 2012-10-26
US8946162B2 (en) 2015-02-03
PT2274005E (pt) 2013-08-27
PL2274005T3 (pl) 2013-12-31
EP2274005A2 (de) 2011-01-19
JP2011516501A (ja) 2011-05-26
EP2644203A1 (de) 2013-10-02

Similar Documents

Publication Publication Date Title
DK2274005T3 (da) Behandling af tumorsygdomme med angiotensin konverterende enzym 2 (ACE2)
PL3050571T3 (pl) Preparat enzymu trawiennego do leczenia rzucawki
DK3130923T3 (da) Terapeutiske fremgangsmåder i forbindelse med cancerstamceller
DK2329012T3 (da) Behandling af slagtilfælde under anvendelse af isolerede placentaceller
DK3998078T3 (da) Dosisoptrapningenzymerstatningsterapi til behandling af mangel på sur sphingomyelinase
DK2620493T3 (da) Mesenkymale stamceller til behandling af CNS-sygdomme
BR112012001325A2 (pt) tratamento de distúrbios do fígado com inibidaores de pi3k
DK2120977T3 (da) Behandling af inflammatoriske sygdomme under anvendelse af placenta-stamceller
DK2300560T3 (da) Termisk behandling af biomasse
BRPI0909367A2 (pt) calçado e método de fabricação do mesmo
BR112012003103A2 (pt) tratamento de células de astrócitos tumorais com inibidor de receptores de endotelina
EP2276795A4 (en) Processing biomass
SG10201802522SA (en) Treatment of pluripotent cells
BRPI1012129A2 (pt) enantiômeros de compostos spiro-oxindol e sua utilização como agentes terapêuticos.
BRPI0919301A2 (pt) aparecimento e gerenciamento de controles específicos de janela
BRPI1014775A2 (pt) tratamento ex vivo de distúrbios imunológicos com inibidores de pkc-teta
BRPI0814894A2 (pt) Diferenciação de células-tronco embrionárias de ser humano.
EP2278999C0 (en) EAR PREPARATIONS FOR THE TREATMENT OF EAR DISEASES AND CONDITIONS
BRPI0811265A2 (pt) Tratamento de sinucleinopatias
DK2056807T3 (da) Behandling af inflammatoriske sygdomme
PT2257155T (pt) Criopreservação de células e tecidos biológicos
EP2382734A4 (en) VERIFICATION OF SOFTWARE APPLICATIONS
IL208979B (en) Humanized antibodies against human interferon-alpha
DK2477747T3 (da) Enzymatisk behandling af husholdningsaffald
EP2561069A4 (en) ENZYM FOR LYSOSOMAL STORAGE DISEASE