DK2203464T3 - Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor - Google Patents

Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor

Info

Publication number
DK2203464T3
DK2203464T3 DK08797301.2T DK08797301T DK2203464T3 DK 2203464 T3 DK2203464 T3 DK 2203464T3 DK 08797301 T DK08797301 T DK 08797301T DK 2203464 T3 DK2203464 T3 DK 2203464T3
Authority
DK
Denmark
Prior art keywords
analyte
identifying
biological sample
mass spectrometric
stress factor
Prior art date
Application number
DK08797301.2T
Other languages
English (en)
Inventor
Christopher William Ward Beecher
Original Assignee
Iroa Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iroa Technologies Llc filed Critical Iroa Technologies Llc
Application granted granted Critical
Publication of DK2203464T3 publication Critical patent/DK2203464T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/109163—Inorganic standards or controls
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DK08797301.2T 2007-08-06 2008-08-06 Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor DK2203464T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95425307P 2007-08-06 2007-08-06
US97692307P 2007-10-02 2007-10-02
US12/186,381 US7820963B2 (en) 2007-08-06 2008-08-05 Method for generation and use of isotopic patterns in mass spectral data of simple organisms
PCT/US2008/072358 WO2009021056A1 (en) 2007-08-06 2008-08-06 Method for generation and use of isotopic patterns in mass spectral data of simple organisms

Publications (1)

Publication Number Publication Date
DK2203464T3 true DK2203464T3 (da) 2014-02-03

Family

ID=40341714

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08797301.2T DK2203464T3 (da) 2007-08-06 2008-08-06 Massespektrometrisk fremgangsmåde til identificering af en analyt fra en biologisk prøve, som er påvirket af en stressfaktor

Country Status (7)

Country Link
US (2) US7820963B2 (da)
EP (2) EP2647996B1 (da)
AU (1) AU2008283904B2 (da)
CA (1) CA2702845C (da)
DK (1) DK2203464T3 (da)
ES (1) ES2453109T3 (da)
WO (1) WO2009021056A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820964B2 (en) * 2007-08-06 2010-10-26 Metabolic Analyses, Inc Method for generation and use of stable isotope patterns in mass spectral data
US8536520B2 (en) * 2007-08-06 2013-09-17 Iroa Technologies Llc Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US7820963B2 (en) * 2007-08-06 2010-10-26 Metabolic Alayses, Inc. Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US8969251B2 (en) * 2007-10-02 2015-03-03 Methabolic Analyses, Inc. Generation and use of isotopic patterns in mass spectral phenotypic comparison of organisms
EP2798658B1 (en) * 2011-12-30 2017-03-01 DH Technologies Development Pte. Ltd. Systems and methods for sequencing peptides by mass spectrometry
EP3283877B1 (en) * 2015-04-14 2024-10-09 Waters Technologies Corporation Structural elucidation of isotopically labeled analytes
CN110392830B (zh) * 2017-02-24 2024-04-16 伊罗亚科技有限公司 用于改进的精度、鉴定和定量的iroa代谢组学工作流程
CA3104627A1 (en) * 2018-06-22 2019-12-26 Iroa Technologies, Llc Method to correct ion source inefficiencies makes sample-to-sample normalization possible

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087815A (en) * 1989-11-08 1992-02-11 Schultz J Albert High resolution mass spectrometry of recoiled ions for isotopic and trace elemental analysis
DK0787492T3 (da) * 1990-03-16 2004-02-02 Us Secretary United States Dep Anvendelse af nitroxider og oxazolidiner til beskyttelse mod ioniserende stråling og oxidativt stress
US5912178A (en) * 1994-02-16 1999-06-15 Wisconsin Alumni Research Foundation Passive measurement of isotopes to monitor health
EP0979306A4 (en) * 1997-02-14 2004-09-01 Univ George Washington ASSAY FOR THE MEASUREMENT OF DNA SYNTHESIS RATES
US6790673B1 (en) 1998-01-29 2004-09-14 Duquesne University Of The Holy Ghost Speciated isotope dilution mass spectrometry of reactive species and related methods
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses
US6391649B1 (en) * 1999-05-04 2002-05-21 The Rockefeller University Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy
US7368710B2 (en) * 2000-02-09 2008-05-06 Xceleron Limited Sample preparation method
WO2002066952A2 (en) 2000-10-19 2002-08-29 Target Discovery, Inc Mass defect labeling for the determination of oligomer sequences
US7045296B2 (en) * 2001-05-08 2006-05-16 Applera Corporation Process for analyzing protein samples
JP3615182B2 (ja) * 2001-11-26 2005-01-26 株式会社東芝 光近接効果補正方法及び光近接効果補正システム
DE60325482D1 (de) * 2002-08-22 2009-02-05 Applera Corp Verfahren zur charakterisierung von biomolekülen mittels resultat-gesteuerter strategie
US6906320B2 (en) 2003-04-02 2005-06-14 Merck & Co., Inc. Mass spectrometry data analysis techniques
US20070158542A1 (en) 2003-05-15 2007-07-12 Electrophoretics Limited Mass spectrometry
AU2004256368B2 (en) * 2003-07-11 2010-08-05 Tatiana A. Egorova-Zachernyuk Compositions and methods for stable isotope labelling of biological compounds
WO2005059566A1 (ja) 2003-12-16 2005-06-30 National Institute Of Advanced Industrial Science And Technology 酸化ストレスマーカー及びその測定法
WO2006096704A2 (en) * 2005-03-07 2006-09-14 Invitrogen Corporation Isotopically-labeled proteome standards
US7465276B2 (en) * 2005-11-30 2008-12-16 Wisconsin Alumni Research Foundation Identification of disease characteristics using isotope ratios in breath
US7794952B2 (en) * 2005-12-15 2010-09-14 George Mason University Biomarker isolation and use thereof to characterize physiological state
US7653496B2 (en) 2006-02-02 2010-01-26 Agilent Technologies, Inc. Feature selection in mass spectral data
US7820964B2 (en) 2007-08-06 2010-10-26 Metabolic Analyses, Inc Method for generation and use of stable isotope patterns in mass spectral data
US7820963B2 (en) 2007-08-06 2010-10-26 Metabolic Alayses, Inc. Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US8536520B2 (en) * 2007-08-06 2013-09-17 Iroa Technologies Llc Method for generation and use of isotopic patterns in mass spectral data of simple organisms
US8969251B2 (en) * 2007-10-02 2015-03-03 Methabolic Analyses, Inc. Generation and use of isotopic patterns in mass spectral phenotypic comparison of organisms
DK2205342T3 (da) 2007-10-02 2014-03-03 Iroa Technologies Llc Generering og anvendelse af isotopiske mønstre i massespektrometrisk fænotypesammenligning af organismer

Also Published As

Publication number Publication date
CA2702845A1 (en) 2009-02-12
EP2203464A4 (en) 2010-09-22
WO2009021056A1 (en) 2009-02-12
US20110084204A1 (en) 2011-04-14
US8168945B2 (en) 2012-05-01
EP2647996B1 (en) 2015-06-03
CA2702845C (en) 2015-09-22
AU2008283904B2 (en) 2013-10-24
EP2203464B1 (en) 2013-12-25
AU2008283904A1 (en) 2009-02-12
US20090039246A1 (en) 2009-02-12
ES2453109T3 (es) 2014-04-04
US7820963B2 (en) 2010-10-26
EP2647996A1 (en) 2013-10-09
EP2203464A1 (en) 2010-07-07

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