DK2189D0 - Kimaere antistoffer samt deres fremstilling og anvendelse - Google Patents

Kimaere antistoffer samt deres fremstilling og anvendelse

Info

Publication number
DK2189D0
DK2189D0 DK002189A DK2189A DK2189D0 DK 2189 D0 DK2189 D0 DK 2189D0 DK 002189 A DK002189 A DK 002189A DK 2189 A DK2189 A DK 2189A DK 2189 D0 DK2189 D0 DK 2189D0
Authority
DK
Denmark
Prior art keywords
preparation
chemical antibodies
antibodies
chemical
Prior art date
Application number
DK002189A
Other languages
English (en)
Other versions
DK2189A (da
DK172444B1 (da
Inventor
Norman Hardman
Laura Lee Gill
Ronald F J De Winter
Kathrin Wagner
Christoph Heusser
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888800077A external-priority patent/GB8800077D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK2189D0 publication Critical patent/DK2189D0/da
Publication of DK2189A publication Critical patent/DK2189A/da
Application granted granted Critical
Publication of DK172444B1 publication Critical patent/DK172444B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198900021A 1988-01-05 1989-01-04 Kimære monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, rekombinant DNA og fremgangsmåde t DK172444B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB888800077A GB8800077D0 (en) 1988-01-05 1988-01-05 Novel chimeric antibodies
GB8800077 1988-01-05
GB888820099A GB8820099D0 (en) 1988-01-05 1988-08-24 Novel chimeric antibodies
GB8820099 1988-08-24

Publications (3)

Publication Number Publication Date
DK2189D0 true DK2189D0 (da) 1989-01-04
DK2189A DK2189A (da) 1989-07-06
DK172444B1 DK172444B1 (da) 1998-07-27

Family

ID=26293262

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900021A DK172444B1 (da) 1988-01-05 1989-01-04 Kimære monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, rekombinant DNA og fremgangsmåde t

Country Status (10)

Country Link
EP (1) EP0323806B1 (da)
JP (1) JPH02154696A (da)
AU (1) AU625613B2 (da)
DE (1) DE3879452T2 (da)
DK (1) DK172444B1 (da)
ES (1) ES2053810T3 (da)
GR (1) GR3007853T3 (da)
HK (1) HK156695A (da)
IE (1) IE62440B1 (da)
PT (1) PT89384B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0407392B2 (en) * 1987-12-31 1998-10-28 Tanox Biosystems, Inc. UNIQUE ANTIGENIC EPITOPES ON IgE-BEARING B LYMPHOCYTES
IL89491A0 (en) * 1988-11-17 1989-09-10 Hybritech Inc Bifunctional chimeric antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
DE3900534A1 (de) * 1989-01-10 1990-07-12 Boehringer Mannheim Gmbh Diagnostischer nachweis unter verwendung von chimaeren antikoerpern
US5081235A (en) * 1989-07-26 1992-01-14 City Of Hope Chimeric anti-cea antibody
US5580774A (en) * 1989-07-31 1996-12-03 Eli Lilly And Company Chimeric antibodies directed against a human glycoprotein antigen
AU632843B2 (en) * 1989-08-10 1993-01-14 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Cat-mouse heterohybridoma and gene fragment coding for constant region of feline immunoglobulin
AU634314B2 (en) * 1989-11-13 1993-02-18 Green Cross Corporation, The Chimeric mouse-human a10 antibody with specificity to a human tumor cell antigen
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
WO1991014438A1 (en) * 1990-03-20 1991-10-03 The Trustees Of Columbia University In The City Of New York Chimeric antibodies with receptor binding ligands in place of their constant region
GB9014932D0 (en) * 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
GB2276169A (en) * 1990-07-05 1994-09-21 Celltech Ltd Antibodies specific for carcinoembryonic antigen
GB9020282D0 (en) 1990-09-17 1990-10-31 Gorman Scott D Altered antibodies and their preparation
US5612034A (en) * 1990-10-03 1997-03-18 Redcell, Inc. Super-globuling for in vivo extended lifetimes
GB9109645D0 (en) * 1991-05-03 1991-06-26 Celltech Ltd Recombinant antibodies
US6797492B2 (en) 1991-05-17 2004-09-28 Merck & Co., Inc. Method for reducing the immunogenicity of antibody variable domains
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
WO1992022653A1 (en) * 1991-06-14 1992-12-23 Genentech, Inc. Method for making humanized antibodies
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
GB9317423D0 (en) * 1993-08-21 1993-10-06 Imp Cancer Res Tech Monoclonal antibodies
EP0753065B1 (en) 1994-03-29 2003-05-14 Celltech Therapeutics Limited Antibodies against e-selectin
CU22615A1 (es) 1994-06-30 2000-02-10 Centro Inmunologia Molecular Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos
US5874540A (en) * 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
AU4373197A (en) * 1996-09-19 1998-04-14 Diagnocure Inc. Recombinant single chain antibodies directed against the gp54 cancer marker, composition comprising same and use thereof
DE19911329A1 (de) * 1998-03-27 2000-09-21 Benes Ivan Friedrich Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung
EP1598671A1 (en) * 1999-10-28 2005-11-23 Agensys, Inc. Diagnosis and therapy of cancer using SGP28-related molecules
EP1572131B1 (en) 2002-10-08 2016-07-06 Immunomedics, Inc. Antibody therapy
EP2210903A1 (en) * 2009-01-21 2010-07-28 Monoclonal Antibodies Therapeutics Anti-CD160 monoclonal antibodies and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations

Also Published As

Publication number Publication date
DK2189A (da) 1989-07-06
DK172444B1 (da) 1998-07-27
EP0323806B1 (en) 1993-03-17
IE62440B1 (en) 1995-02-08
EP0323806A1 (en) 1989-07-12
GR3007853T3 (da) 1993-08-31
IE890019L (en) 1989-07-05
DE3879452D1 (de) 1993-04-22
PT89384A (pt) 1990-02-08
HK156695A (en) 1995-10-13
AU625613B2 (en) 1992-07-16
AU2759588A (en) 1989-07-06
DE3879452T2 (de) 1993-07-15
ES2053810T3 (es) 1994-08-01
JPH02154696A (ja) 1990-06-14
PT89384B (pt) 1993-09-30

Similar Documents

Publication Publication Date Title
DK2189D0 (da) Kimaere antistoffer samt deres fremstilling og anvendelse
DK575687D0 (da) Bicycliske forbindelser samt deres fremstilling og anvendelse
DK317588A (da) 2-anilino-pyrimidin-derivat samt deres fremstilling og anvendelse
DK391785A (da) Monoklonale antistoffer samt deres fremstilling og anvendelse
DK381287A (da) Polypeptider samt deres fremstilling og anvendelse
DK420785D0 (da) 13-halogen- eller 13-hydroxymilbemyciner samt deres fremstilling og anvendelse
DK35884A (da) Lactampeptider samt deres fremstilling og anvendelse
DK248285A (da) Polypeptider samt deres fremstilling og anvendelse
DK533087A (da) Anthracyklinglykosider, deres fremstilling, mellemprodukter deraf samt praeparater indeholdende disse og deres anvendelse
DK289287D0 (da) 1-phenylalkylimidazol-4- og/eller -5-carboxamider samt deres fremstiling og anvendelse
DK172486D0 (da) Heterocyclyl-penem-forbindelser samt deres fremstilling og anvendelse
DK189584D0 (da) (5alfa)-20-spirox-1-en-3-oner samt deres fremstilling og anvendelse
DK634089D0 (da) Polyhydroxybenzyloxypropanolaminer og deres anvendelse
DK25989D0 (da) 4-alkyl-1,4-dihydropyridiner samt deres fremstilling og anvendelse
DK35984D0 (da) Lactampeptider samt deres fremstilling og anvendelse
DK8887D0 (da) Substituerede 1,3,5-oxadiazin-2-oner samt deres fremstilling og anvendelse
DK206686A (da) Acylaminomethyl-penem-forbindelser samt deres fremstilling og anvendelse
DK437986D0 (da) 1-amino-3-phenyl-propan-2-ol-derivater samt deres fremstilling og anvendelse
DK403889D0 (da) Benzazolderivater samt deres fremstilling og anvendelse
DK13588A (da) Heterocyclylalkyl-2-penem-forbindelser samt deres fremstilling og anvendelse
DK447687A (da) Urdamycin g og derivater deraf samt deres fremstilling og anvendelse
DK439188A (da) Sulfonerede chlorbenzidiner samt deres fremstilling og anvendelse
DK117587A (da) 5-acyloxy-13beta-alkyl-milbemycin-derivater samt deres fremstilling og anvendelse
DK432187D0 (da) Penemforbindelser samt deres fremstilling og anvendelse
DK482385D0 (da) Fluorerede resorcinolethere samt deres fremstilling og anvendelse

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed