DK218583A - Pyrrolo(3,4-d)(2)benzazepinderivater, n-oxider og farmaceutisk acceptable salte deraf samt fremgangsmaade til deres fremstilling - Google Patents

Pyrrolo(3,4-d)(2)benzazepinderivater, n-oxider og farmaceutisk acceptable salte deraf samt fremgangsmaade til deres fremstilling Download PDF

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Publication number
DK218583A
DK218583A DK218583A DK218583A DK218583A DK 218583 A DK218583 A DK 218583A DK 218583 A DK218583 A DK 218583A DK 218583 A DK218583 A DK 218583A DK 218583 A DK218583 A DK 218583A
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DK
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Prior art keywords
pyrrolo
oxides
procedure
preparation
acceptable salts
Prior art date
Application number
DK218583A
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English (en)
Other versions
DK218583D0 (da
Inventor
Rodney Ian Fryer
Eugene J Trybulski
Armin Walser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK218583D0 publication Critical patent/DK218583D0/da
Publication of DK218583A publication Critical patent/DK218583A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK218583A 1982-05-18 1983-05-17 Pyrrolo(3,4-d)(2)benzazepinderivater, n-oxider og farmaceutisk acceptable salte deraf samt fremgangsmaade til deres fremstilling DK218583A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37940082A 1982-05-18 1982-05-18
US39314282A 1982-06-28 1982-06-28

Publications (2)

Publication Number Publication Date
DK218583D0 DK218583D0 (da) 1983-05-17
DK218583A true DK218583A (da) 1983-11-19

Family

ID=27008604

Family Applications (1)

Application Number Title Priority Date Filing Date
DK218583A DK218583A (da) 1982-05-18 1983-05-17 Pyrrolo(3,4-d)(2)benzazepinderivater, n-oxider og farmaceutisk acceptable salte deraf samt fremgangsmaade til deres fremstilling

Country Status (9)

Country Link
EP (1) EP0094668B1 (da)
AU (1) AU558354B2 (da)
CA (1) CA1202970A (da)
DE (1) DE3372369D1 (da)
DK (1) DK218583A (da)
IE (1) IE55134B1 (da)
IL (1) IL68711A (da)
NZ (1) NZ204242A (da)
PH (1) PH19004A (da)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
US4354973A (en) * 1980-08-05 1982-10-19 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepines

Also Published As

Publication number Publication date
DK218583D0 (da) 1983-05-17
AU558354B2 (en) 1987-01-29
IE831148L (en) 1983-11-18
EP0094668A3 (en) 1985-01-16
CA1202970A (en) 1986-04-08
NZ204242A (en) 1986-08-08
IE55134B1 (en) 1990-06-06
DE3372369D1 (de) 1987-08-13
EP0094668A2 (de) 1983-11-23
EP0094668B1 (de) 1987-07-08
AU1460583A (en) 1983-11-24
IL68711A (en) 1986-12-31
IL68711A0 (en) 1983-09-30
PH19004A (en) 1985-12-03

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AHB Application shelved due to non-payment