DK214681A - Fremgangsmaade til fremstilling af pyrazinyl1,2,4-oxadiazoler og kvaternaere salte deraf - Google Patents
Fremgangsmaade til fremstilling af pyrazinyl1,2,4-oxadiazoler og kvaternaere salte derafInfo
- Publication number
- DK214681A DK214681A DK214681A DK214681A DK214681A DK 214681 A DK214681 A DK 214681A DK 214681 A DK214681 A DK 214681A DK 214681 A DK214681 A DK 214681A DK 214681 A DK214681 A DK 214681A
- Authority
- DK
- Denmark
- Prior art keywords
- pyrazinyl1
- oxadiazoles
- procedure
- preparation
- quaternary salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/151,494 US4309540A (en) | 1980-05-19 | 1980-05-19 | Substituted pyrazinyl-1,2,4-oxadiazoles |
| US06/244,509 US4362724A (en) | 1980-05-19 | 1981-03-16 | Method of treating edema and hypertension and pharmaceutical composition therefor in which the active ingredient comprises a novel substituted pyrazinyl-1,2,4-oxadiazole and a kaliuretic diuretic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK214681A true DK214681A (da) | 1981-11-20 |
Family
ID=26848697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK214681A DK214681A (da) | 1980-05-19 | 1981-05-14 | Fremgangsmaade til fremstilling af pyrazinyl1,2,4-oxadiazoler og kvaternaere salte deraf |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4362724A (es) |
| EP (1) | EP0040422B1 (es) |
| AU (1) | AU536493B2 (es) |
| DE (1) | DE3161767D1 (es) |
| DK (1) | DK214681A (es) |
| ES (1) | ES502282A0 (es) |
| FI (1) | FI811421L (es) |
| GR (1) | GR74903B (es) |
| IE (1) | IE51288B1 (es) |
| NO (1) | NO811667L (es) |
| NZ (1) | NZ197055A (es) |
| PT (1) | PT73016B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US6858615B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| AU2013363218B2 (en) | 2012-12-17 | 2018-03-15 | Parion Sciences, Inc. | Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration |
| KR20150095870A (ko) | 2012-12-17 | 2015-08-21 | 패리온 사이언스 인코퍼레이티드 | 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물 |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL299931A (es) * | 1962-10-30 | |||
| MC641A1 (fr) * | 1967-03-08 | 1967-12-05 | Mauvernay Roland Yves | Nouveaux composés chimiques et procédé pour leur préparation |
| US4196292A (en) * | 1977-06-29 | 1980-04-01 | Merck & Co., Inc. | 6-Substituted amiloride derivatives |
| EP0009054A1 (en) * | 1978-09-19 | 1980-04-02 | Merck & Co. Inc. | N-Pyrazinecarbonyl-N'-substituted-sulfamoyl-guanidine and processes for preparing same |
-
1981
- 1981-03-16 US US06/244,509 patent/US4362724A/en not_active Expired - Fee Related
- 1981-05-06 AU AU70180/81A patent/AU536493B2/en not_active Ceased
- 1981-05-08 FI FI811421A patent/FI811421L/fi not_active Application Discontinuation
- 1981-05-11 NZ NZ197055A patent/NZ197055A/en unknown
- 1981-05-11 PT PT73016A patent/PT73016B/pt unknown
- 1981-05-14 DK DK214681A patent/DK214681A/da not_active Application Discontinuation
- 1981-05-14 GR GR64954A patent/GR74903B/el unknown
- 1981-05-15 NO NO811667A patent/NO811667L/no unknown
- 1981-05-18 DE DE8181103800T patent/DE3161767D1/de not_active Expired
- 1981-05-18 IE IE1102/81A patent/IE51288B1/en unknown
- 1981-05-18 EP EP81103800A patent/EP0040422B1/en not_active Expired
- 1981-05-18 ES ES502282A patent/ES502282A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8207528A1 (es) | 1982-10-01 |
| PT73016B (en) | 1983-08-08 |
| NO811667L (no) | 1981-11-20 |
| NZ197055A (en) | 1984-07-31 |
| US4362724A (en) | 1982-12-07 |
| IE811102L (en) | 1981-11-19 |
| IE51288B1 (en) | 1986-11-26 |
| PT73016A (en) | 1981-06-01 |
| AU536493B2 (en) | 1984-05-10 |
| GR74903B (es) | 1984-07-12 |
| EP0040422B1 (en) | 1983-12-28 |
| ES502282A0 (es) | 1982-10-01 |
| DE3161767D1 (en) | 1984-02-02 |
| AU7018081A (en) | 1981-11-26 |
| FI811421L (fi) | 1981-11-20 |
| EP0040422A1 (en) | 1981-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |