DK1957461T3 - Bisamidhæmmere the hedgehog-signalling - Google Patents

Bisamidhæmmere the hedgehog-signalling Download PDF

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Publication number
DK1957461T3
DK1957461T3 DK06844364.7T DK06844364T DK1957461T3 DK 1957461 T3 DK1957461 T3 DK 1957461T3 DK 06844364 T DK06844364 T DK 06844364T DK 1957461 T3 DK1957461 T3 DK 1957461T3
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chloro
phenyl
nicotinamide
methyl
alkyl
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DK06844364.7T
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Danish (da)
English (en)
Inventor
Richard A Goldsmith
Daniel P Sutherlin
Kirk D Robarge
Alan G Olivero
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Genentech Inc
Curis Inc
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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DK06844364.7T 2005-11-14 2006-11-14 Bisamidhæmmere the hedgehog-signalling DK1957461T3 (en)

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EP1957461A1 (en) 2008-08-20
WO2007059157A1 (en) 2007-05-24
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CA2629814A1 (en) 2007-05-24
ES2604539T3 (es) 2017-03-07
US8101610B2 (en) 2012-01-24
JP2013079283A (ja) 2013-05-02
EP1957461B1 (en) 2016-11-02
US20080269215A1 (en) 2008-10-30
AU2006315467A1 (en) 2007-05-24
JP2009516685A (ja) 2009-04-23

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