DK189189A - AZELASTIC CONTAINED ACTIVE SUBSTANCES WITH CONTROLS - Google Patents
AZELASTIC CONTAINED ACTIVE SUBSTANCES WITH CONTROLSInfo
- Publication number
- DK189189A DK189189A DK189189A DK189189A DK189189A DK 189189 A DK189189 A DK 189189A DK 189189 A DK189189 A DK 189189A DK 189189 A DK189189 A DK 189189A DK 189189 A DK189189 A DK 189189A
- Authority
- DK
- Denmark
- Prior art keywords
- azelastic
- controls
- azelastine
- active substances
- release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Switches With Compound Operations (AREA)
- Polyurethanes Or Polyureas (AREA)
- Rotary Pumps (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Azelastine-containing pharmaceutical compositions with controlled release of active substance using a release-delaying component, there being 0.001 to 800 parts of release-delaying component for one part by weight of azelastine (as base), and it also being possible for the azelastine to be in the form of its physiologically tolerated salts, and the rate of azelastine release being between 0.05 and 5 mg per hour.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3813244 | 1988-04-20 | ||
DE3813244 | 1988-04-20 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK189189D0 DK189189D0 (en) | 1989-04-19 |
DK189189A true DK189189A (en) | 1989-10-21 |
DK172235B1 DK172235B1 (en) | 1998-02-02 |
Family
ID=6352451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK189189A DK172235B1 (en) | 1988-04-20 | 1989-04-19 | Azelastine-containing controlled-release drug |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0338444B1 (en) |
JP (1) | JP2950845B2 (en) |
AT (1) | ATE97572T1 (en) |
AU (1) | AU3318389A (en) |
CA (1) | CA1325976C (en) |
DE (1) | DE58906232D1 (en) |
DK (1) | DK172235B1 (en) |
ES (1) | ES2060685T3 (en) |
FI (1) | FI891865A (en) |
HK (1) | HK134494A (en) |
HU (1) | HU202403B (en) |
IE (1) | IE62778B1 (en) |
MC (1) | MC2025A1 (en) |
PT (1) | PT90308B (en) |
ZA (1) | ZA892877B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9003903D0 (en) * | 1990-12-07 | 1990-12-07 | Astra Ab | NEW PHARMACEUTICAL FORMULATIONS |
DE4207234A1 (en) * | 1992-03-07 | 1993-09-09 | Asta Medica Ag | NEW AMINOCARBONIC ACID DERIVATIVES WITH ANTIALLERGIC / ANTIASTHMIC EFFECT AND METHOD FOR THE PRODUCTION THEREOF |
JPH0710747A (en) * | 1993-04-28 | 1995-01-13 | Takeda Chem Ind Ltd | Solid preparation and its production |
GB9514842D0 (en) * | 1995-07-20 | 1995-09-20 | Smithkline Beecham Plc | Novel formulation |
JP4138910B2 (en) | 1997-07-02 | 2008-08-27 | 帝國製薬株式会社 | Transdermal preparation containing azelastine hydrochloride with good transdermal absorbability and low skin irritation |
UA67802C2 (en) * | 1998-10-23 | 2004-07-15 | Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А. | CONTROLLED-RELEASE FORMULATIONS FOR ORAL ADMINISTRATION CONTAINING cGMP PDE-5 INHIBITOR (VARIANTS), METHOD FOR ITS PREPARATION AND METHOD FOR TREATING ERECTILE DYSFUNCTION |
ID29852A (en) | 1998-11-02 | 2001-10-18 | Elan Corp Plc Cs | COMPLEXION OF MULTI PARTICULATION MODIFICATION |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
AU764453B2 (en) | 1999-10-29 | 2003-08-21 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
CN101317825A (en) | 2000-10-30 | 2008-12-10 | 欧罗赛铁克股份有限公司 | Controlled release hydrocodone formulations |
EP1396263A1 (en) * | 2002-08-09 | 2004-03-10 | Warner-Lambert Company | Film coating for tablets and caplets |
JP2006523613A (en) * | 2002-12-20 | 2006-10-19 | エスティ.ジェイムス アソシエイト エルエルシー/フェイバー リサーチ シリーズ | Coated particles for sustained release pharmaceutical administration |
DK2522365T3 (en) * | 2004-11-24 | 2017-02-06 | Meda Pharmaceuticals Inc | Compositions comprising azelastine and methods for its use |
MX2015013457A (en) | 2013-03-21 | 2016-05-16 | Eupraxia Pharmaceuticals USA LLC | Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith. |
US11351124B2 (en) | 2015-10-27 | 2022-06-07 | Eupraxia Pharmaceuticals Inc. | Sustained release of formulations of local anesthetics |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE49205T1 (en) * | 1984-09-14 | 1990-01-15 | Asta Pharma Ag | SUBSTITUTE BENZYLPHTHALAZINONE DERIVATIVES. |
-
1989
- 1989-04-11 MC MC892044A patent/MC2025A1/en unknown
- 1989-04-14 EP EP89106685A patent/EP0338444B1/en not_active Expired - Lifetime
- 1989-04-14 ES ES89106685T patent/ES2060685T3/en not_active Expired - Lifetime
- 1989-04-14 DE DE89106685T patent/DE58906232D1/en not_active Expired - Lifetime
- 1989-04-14 AT AT89106685T patent/ATE97572T1/en not_active IP Right Cessation
- 1989-04-19 PT PT90308A patent/PT90308B/en not_active IP Right Cessation
- 1989-04-19 HU HU891912A patent/HU202403B/en not_active IP Right Cessation
- 1989-04-19 ZA ZA892877A patent/ZA892877B/en unknown
- 1989-04-19 AU AU33183/89A patent/AU3318389A/en not_active Abandoned
- 1989-04-19 IE IE126389A patent/IE62778B1/en not_active IP Right Cessation
- 1989-04-19 DK DK189189A patent/DK172235B1/en not_active IP Right Cessation
- 1989-04-19 CA CA000597169A patent/CA1325976C/en not_active Expired - Lifetime
- 1989-04-19 FI FI891865A patent/FI891865A/en not_active Application Discontinuation
- 1989-04-20 JP JP1099031A patent/JP2950845B2/en not_active Expired - Lifetime
-
1994
- 1994-12-01 HK HK134494A patent/HK134494A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2950845B2 (en) | 1999-09-20 |
EP0338444B1 (en) | 1993-11-24 |
IE891263L (en) | 1989-10-20 |
EP0338444A1 (en) | 1989-10-25 |
FI891865A0 (en) | 1989-04-19 |
ZA892877B (en) | 1989-12-27 |
AU3318389A (en) | 1989-10-26 |
PT90308B (en) | 1994-10-31 |
DE58906232D1 (en) | 1994-01-05 |
ATE97572T1 (en) | 1993-12-15 |
CA1325976C (en) | 1994-01-11 |
HU202403B (en) | 1991-03-28 |
DK189189D0 (en) | 1989-04-19 |
JPH01311024A (en) | 1989-12-15 |
HUT49808A (en) | 1989-11-28 |
DK172235B1 (en) | 1998-02-02 |
FI891865A (en) | 1989-10-21 |
PT90308A (en) | 1989-11-10 |
MC2025A1 (en) | 1990-04-25 |
IE62778B1 (en) | 1995-02-22 |
ES2060685T3 (en) | 1994-12-01 |
HK134494A (en) | 1994-12-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |