DK186286A - BENZOIC ACID DERIVATIVES, PHARMACEUTICALS CONTAINING THESE DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE DERIVATIVES AND MEDICINAL PRODUCTS - Google Patents

BENZOIC ACID DERIVATIVES, PHARMACEUTICALS CONTAINING THESE DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE DERIVATIVES AND MEDICINAL PRODUCTS Download PDF

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Publication number
DK186286A
DK186286A DK186286A DK186286A DK186286A DK 186286 A DK186286 A DK 186286A DK 186286 A DK186286 A DK 186286A DK 186286 A DK186286 A DK 186286A DK 186286 A DK186286 A DK 186286A
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DK
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Prior art keywords
derivatives
procedures
preparation
benzoic acid
medicinal products
Prior art date
Application number
DK186286A
Other languages
Danish (da)
Other versions
DK186286D0 (en
Inventor
Werner Vollenberg
Oswald Zimmer
Gerriet Loschen
Erwin Kiesewetter
Ulrich Seipp
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of DK186286D0 publication Critical patent/DK186286D0/en
Publication of DK186286A publication Critical patent/DK186286A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/04—Acyclic alcohols with carbon-to-carbon triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

Forbindelserne er specifikt virkende, tilstrækkeligt stabile 5-lipoxygenase-inhibitorer og navnlig anvendelige i lægemiddelkompositioner til behandling af patologiske tilstande, ved hvilke leukotriener er delagtige som mediatorer.The compounds are specifically effective, sufficiently stable 5-lipoxygenase inhibitors and especially useful in drug compositions for the treatment of pathological conditions in which leukotrienes are involved as mediators.

DK186286A 1985-04-27 1986-04-23 BENZOIC ACID DERIVATIVES, PHARMACEUTICALS CONTAINING THESE DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE DERIVATIVES AND MEDICINAL PRODUCTS DK186286A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3515278 1985-04-27
DE19853515278 DE3515278A1 (en) 1985-04-27 1985-04-27 NEW BENZOESAEUR DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR PRODUCING THESE COMPOUNDS AND MEDICINAL PRODUCTS

Publications (2)

Publication Number Publication Date
DK186286D0 DK186286D0 (en) 1986-04-23
DK186286A true DK186286A (en) 1986-10-28

Family

ID=6269293

Family Applications (1)

Application Number Title Priority Date Filing Date
DK186286A DK186286A (en) 1985-04-27 1986-04-23 BENZOIC ACID DERIVATIVES, PHARMACEUTICALS CONTAINING THESE DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE DERIVATIVES AND MEDICINAL PRODUCTS

Country Status (15)

Country Link
EP (1) EP0199985A3 (en)
JP (1) JPS6242947A (en)
KR (1) KR860008155A (en)
AU (1) AU582433B2 (en)
DD (1) DD250313A5 (en)
DE (1) DE3515278A1 (en)
DK (1) DK186286A (en)
ES (1) ES8703402A1 (en)
FI (1) FI861414A (en)
GR (1) GR860442B (en)
HU (1) HU196163B (en)
IL (1) IL77989A (en)
PT (1) PT82393B (en)
SU (1) SU1450734A3 (en)
ZA (1) ZA861490B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642972B1 (en) * 1989-02-14 1994-08-05 Inst Nat Sante Rech Med AGENTS FOR THE DIAGNOSIS AND TREATMENT OF MELANOMAS, HALOGENATED AROMATIC DERIVATIVES SUITABLE FOR USE AS SUCH AGENTS AND THEIR PREPARATION
DE4023742A1 (en) * 1990-07-26 1992-01-30 Gruenenthal Gmbh SUBSTITUTED PHENYLACETYLENES, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR PRODUCING THESE COMPOUNDS AND MEDICINAL PRODUCTS
DE4120698A1 (en) * 1991-06-22 1992-12-24 Gruenenthal Gmbh New phenoxy-alkanol derivs. which are 5-lipoxygenase inhibitors - used to treat asthma, thrombosis, shock, ischaemic coronary infarction, etc.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE7897T1 (en) * 1979-09-05 1984-06-15 Glaxo Group Limited PHENOL DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US4331683A (en) * 1980-10-29 1982-05-25 Pfizer Inc. Carboxamide compounds as SRS-A antagonists
EP0056172B1 (en) * 1981-01-09 1985-04-03 FISONS plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
IE54269B1 (en) * 1981-12-30 1989-08-02 Ici America Inc Pharmaceutically active phenylcarboxylic acid derivatives
US4507498A (en) * 1982-04-09 1985-03-26 Hoffmann-La Roche Inc. Phenoxycarboxylic acids
DE3228629A1 (en) * 1982-07-31 1984-02-02 Reifenrath, Rainer Richard Otto, Dr., 3104 Unterlüß Pharmaceutical product for the treatment of the airways and process for its production
IL69691A (en) * 1982-09-23 1988-01-31 Merck Frosst Canada Inc Leukotriene antagonists,their preparation and pharmaceutical compositions containing them
DD242802A1 (en) * 1983-02-28 1987-02-11 Univ Berlin Humboldt PROCESS FOR PREPARING NEW W (2'-NAPHTHOXY) HYDROXAMIC ACIDS CONTAINING PHARMACEUTICAL PREPARATIONS AND THEIR SALTS
US4539419A (en) * 1983-05-02 1985-09-03 Hoffmann-La Roche Inc. Naphthalenyloxy substituted carboxylic acids
US4499295A (en) * 1983-05-09 1985-02-12 G. D. Searle & Co. Protease inhibitors

Also Published As

Publication number Publication date
PT82393B (en) 1987-09-10
HUT40611A (en) 1987-01-28
IL77989A (en) 1989-08-15
KR860008155A (en) 1986-11-12
HU196163B (en) 1988-10-28
GR860442B (en) 1986-06-16
DD250313A5 (en) 1987-10-08
EP0199985A3 (en) 1988-06-22
FI861414A0 (en) 1986-04-01
ES553731A0 (en) 1987-02-16
JPS6242947A (en) 1987-02-24
DK186286D0 (en) 1986-04-23
ZA861490B (en) 1986-10-29
DE3515278A1 (en) 1986-10-30
EP0199985A2 (en) 1986-11-05
ES8703402A1 (en) 1987-02-16
SU1450734A3 (en) 1989-01-07
AU5636686A (en) 1986-11-06
PT82393A (en) 1986-05-01
AU582433B2 (en) 1989-03-23
FI861414A (en) 1986-10-28

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