DK1711473T3 - Substituting N-cyclohexyl heterocyclic compounds as well as their physiologically compatible salts and physiologically functional derivatives - Google Patents

Substituting N-cyclohexyl heterocyclic compounds as well as their physiologically compatible salts and physiologically functional derivatives

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Publication number
DK1711473T3
DK1711473T3 DK05707002T DK05707002T DK1711473T3 DK 1711473 T3 DK1711473 T3 DK 1711473T3 DK 05707002 T DK05707002 T DK 05707002T DK 05707002 T DK05707002 T DK 05707002T DK 1711473 T3 DK1711473 T3 DK 1711473T3
Authority
DK
Denmark
Prior art keywords
physiologically
substituting
cyclohexyl
well
heterocyclic compounds
Prior art date
Application number
DK05707002T
Other languages
Danish (da)
Inventor
Lothar Schwink
Thomas Boehme
Matthias Gossel
Siegfried Stengelin
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1711473T3 publication Critical patent/DK1711473T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/08Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK05707002T 2004-01-25 2005-01-25 Substituting N-cyclohexyl heterocyclic compounds as well as their physiologically compatible salts and physiologically functional derivatives DK1711473T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004003811A DE102004003811A1 (en) 2004-01-25 2004-01-25 Substituted N-cyclohexylimidazolinones, processes for their preparation and their use as medicaments
PCT/EP2005/000700 WO2005070898A1 (en) 2004-01-25 2005-01-25 Substituted n-cyclohexyl imidazolinones having an mch-modulatory effect

Publications (1)

Publication Number Publication Date
DK1711473T3 true DK1711473T3 (en) 2008-05-26

Family

ID=34745115

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05707002T DK1711473T3 (en) 2004-01-25 2005-01-25 Substituting N-cyclohexyl heterocyclic compounds as well as their physiologically compatible salts and physiologically functional derivatives

Country Status (26)

Country Link
EP (1) EP1711473B1 (en)
JP (1) JP2007518771A (en)
KR (1) KR20060128955A (en)
CN (1) CN1934090B (en)
AR (1) AR047453A1 (en)
AT (1) ATE383342T1 (en)
AU (1) AU2005206308A1 (en)
BR (1) BRPI0507104A (en)
CA (1) CA2554233A1 (en)
CY (1) CY1107429T1 (en)
DE (2) DE102004003811A1 (en)
DK (1) DK1711473T3 (en)
ES (1) ES2297667T3 (en)
HR (1) HRP20080077T3 (en)
IL (1) IL176917A0 (en)
MA (1) MA28345A1 (en)
MY (1) MY139107A (en)
NO (1) NO20063757L (en)
PE (1) PE20051091A1 (en)
PL (1) PL1711473T3 (en)
PT (1) PT1711473E (en)
RS (1) RS50543B (en)
RU (1) RU2006130626A (en)
TW (1) TW200604182A (en)
UY (1) UY28726A1 (en)
WO (1) WO2005070898A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2008129679A (en) 2005-12-21 2010-01-27 Янссен Фармацевтика Н.В. (Be) NEW SUBSTITUTED PYRAZINONIC DERIVATIVES FOR USE IN SIT-1-MEDIATED DISEASES
RU2009108280A (en) 2006-08-08 2010-09-20 Санофи-Авентис (Fr) Arylamino-arylalkyl-substituted imidazolidine-2,4-dione, methods for their preparation containing these compounds and their use
AU2007328979B2 (en) 2006-12-05 2013-05-09 Janssen Pharmaceutica N.V. Novel substituted diaza spiro pyridinone derivatives for use in MCH-1 mediated diseases
KR100893394B1 (en) * 2007-05-11 2009-04-17 한국화학연구원 Imidazole derivatives having aryl piperidine substituents, method for the preparation thereof, and pharmaceutical compositions containing them
UY31968A (en) 2008-07-09 2010-01-29 Sanofi Aventis NEW HETEROCYCLIC DERIVATIVES, THEIR PROCESSES FOR THEIR PREPARATION, AND THEIR THERAPEUTIC USES
DE102008060967A1 (en) * 2008-12-06 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Substituted phenylsulfonyltriazolones and their use
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
SG178880A1 (en) 2009-08-26 2012-04-27 Sanofi Sa Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
EP2683699B1 (en) 2011-03-08 2015-06-24 Sanofi Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2012120052A1 (en) 2011-03-08 2012-09-13 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
US8809324B2 (en) 2011-03-08 2014-08-19 Sanofi Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
WO2012120057A1 (en) 2011-03-08 2012-09-13 Sanofi Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
WO2012120054A1 (en) 2011-03-08 2012-09-13 Sanofi Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8809325B2 (en) 2011-03-08 2014-08-19 Sanofi Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
PL223830B1 (en) 2012-04-03 2016-11-30 Univ Jagielloński Derivatives of aromatic imidazolidinones and their use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2312637T3 (en) * 2001-12-04 2009-03-01 Schering Corporation DERIVATIVES OF N-ARIL-N`-ARILCICLOALQUIL-UREA AS MCH ANTAGONISTS FOR THE TREATMENT OF OBESITY.
DE10233817A1 (en) * 2002-07-25 2004-02-12 Aventis Pharma Deutschland Gmbh Substituted diaryl heterocycles, process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
UY28726A1 (en) 2005-08-31
ES2297667T3 (en) 2008-05-01
AR047453A1 (en) 2006-01-18
TW200604182A (en) 2006-02-01
AU2005206308A1 (en) 2005-08-04
KR20060128955A (en) 2006-12-14
RS50543B (en) 2010-05-07
RU2006130626A (en) 2008-02-27
PL1711473T3 (en) 2008-05-30
IL176917A0 (en) 2006-12-10
DE502005002497D1 (en) 2008-02-21
WO2005070898A1 (en) 2005-08-04
CA2554233A1 (en) 2005-08-04
MA28345A1 (en) 2006-12-01
JP2007518771A (en) 2007-07-12
CN1934090A (en) 2007-03-21
BRPI0507104A (en) 2007-06-19
DE102004003811A1 (en) 2005-08-11
EP1711473A1 (en) 2006-10-18
ATE383342T1 (en) 2008-01-15
CN1934090B (en) 2010-04-07
HRP20080077T3 (en) 2008-03-31
MY139107A (en) 2009-08-28
NO20063757L (en) 2006-10-11
EP1711473B1 (en) 2008-01-09
CY1107429T1 (en) 2012-12-19
PT1711473E (en) 2008-03-07
PE20051091A1 (en) 2006-01-23

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