DK1636261T3 - Thrombopoietinproteiner med forbedrede egenskaber - Google Patents
Thrombopoietinproteiner med forbedrede egenskaberInfo
- Publication number
- DK1636261T3 DK1636261T3 DK04740298T DK04740298T DK1636261T3 DK 1636261 T3 DK1636261 T3 DK 1636261T3 DK 04740298 T DK04740298 T DK 04740298T DK 04740298 T DK04740298 T DK 04740298T DK 1636261 T3 DK1636261 T3 DK 1636261T3
- Authority
- DK
- Denmark
- Prior art keywords
- tpo
- improved
- thrombopoietin
- proteins
- improved properties
- Prior art date
Links
- 102000036693 Thrombopoietin Human genes 0.000 title abstract 5
- 108010041111 Thrombopoietin Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 101000799461 Homo sapiens Thrombopoietin Proteins 0.000 abstract 2
- 241000282412 Homo Species 0.000 abstract 1
- 101000694103 Homo sapiens Thyroid peroxidase Proteins 0.000 abstract 1
- 102000009786 Immunoglobulin Constant Regions Human genes 0.000 abstract 1
- 108010009817 Immunoglobulin Constant Regions Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000053400 human TPO Human genes 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03014331 | 2003-06-26 | ||
| PCT/EP2004/006887 WO2005000891A2 (en) | 2003-06-26 | 2004-06-25 | Thrombopoietin proteins with improved properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1636261T3 true DK1636261T3 (da) | 2007-11-12 |
Family
ID=33547598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04740298T DK1636261T3 (da) | 2003-06-26 | 2004-06-25 | Thrombopoietinproteiner med forbedrede egenskaber |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7541439B2 (da) |
| EP (1) | EP1636261B1 (da) |
| AT (1) | ATE368687T1 (da) |
| DE (1) | DE602004007924T2 (da) |
| DK (1) | DK1636261T3 (da) |
| ES (1) | ES2289528T3 (da) |
| PL (1) | PL1636261T3 (da) |
| PT (1) | PT1636261E (da) |
| WO (1) | WO2005000891A2 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007098547A1 (en) * | 2006-03-01 | 2007-09-07 | Apollo Life Sciences Limited | A molecule and chimeric molecules thereof |
| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| US20090010966A1 (en) * | 2007-06-21 | 2009-01-08 | Angelica Therapeutics, Inc. | Modified diphtheria toxins |
| DK2190473T3 (da) | 2007-08-15 | 2013-03-25 | Circassia Ltd | Peptid med reduceret dimerdannelse |
| EP2268297A4 (en) * | 2008-02-29 | 2011-11-16 | Angelica Therapeutics Inc | MODIFIED TOXINS |
| KR101040396B1 (ko) * | 2009-01-20 | 2011-06-09 | 한올바이오파마주식회사 | 변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법 |
| JP6684490B2 (ja) | 2012-01-09 | 2020-04-22 | ザ・スクリップス・リサーチ・インスティテュート | 超長相補性決定領域及びその使用 |
| EP2943512A4 (en) | 2013-01-11 | 2016-06-01 | California Inst Biomedical Res | FUSION BOVINE ANTIBODIES |
| US10059750B2 (en) | 2013-03-15 | 2018-08-28 | Angelica Therapeutics, Inc. | Modified toxins |
| AU2015269210A1 (en) * | 2014-06-06 | 2016-12-08 | The California Institute For Biomedical Research | Methods of constructing amino terminal immunoglobulin fusion proteins and compositions thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6284471B1 (en) * | 1991-03-18 | 2001-09-04 | New York University Medical Center | Anti-TNFa antibodies and assays employing anti-TNFa antibodies |
| US6238890B1 (en) * | 1994-02-18 | 2001-05-29 | Washington University | Single chain forms of the glycoprotein hormone quartet |
| US5879673A (en) * | 1996-01-25 | 1999-03-09 | Genentech, Inc. | Administration of thrombopoietin on a single day only |
| US6458563B1 (en) * | 1996-06-26 | 2002-10-01 | Emory University | Modified factor VIII |
| RU2003127409A (ru) * | 2001-02-26 | 2005-04-10 | Мерк Патент ГмбХ (DE) | Модифицированный тромбопоэтин с уменьшенной иммуногенностью |
| CN100390282C (zh) * | 2001-12-04 | 2008-05-28 | 默克专利有限公司 | 具有调节的选择性的il-2融合蛋白 |
| EP1578772B1 (en) * | 2002-05-01 | 2010-05-12 | Danisco US Inc. | Cytokines and cytokine receptors with reduced immunogenicity |
-
2004
- 2004-06-25 AT AT04740298T patent/ATE368687T1/de not_active IP Right Cessation
- 2004-06-25 DE DE602004007924T patent/DE602004007924T2/de not_active Expired - Fee Related
- 2004-06-25 ES ES04740298T patent/ES2289528T3/es not_active Expired - Lifetime
- 2004-06-25 DK DK04740298T patent/DK1636261T3/da active
- 2004-06-25 EP EP04740298A patent/EP1636261B1/en not_active Expired - Lifetime
- 2004-06-25 WO PCT/EP2004/006887 patent/WO2005000891A2/en active IP Right Grant
- 2004-06-25 PT PT04740298T patent/PT1636261E/pt unknown
- 2004-06-25 PL PL04740298T patent/PL1636261T3/pl unknown
- 2004-06-25 US US10/561,097 patent/US7541439B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005000891A3 (en) | 2005-04-21 |
| PL1636261T3 (pl) | 2007-12-31 |
| PT1636261E (pt) | 2007-11-08 |
| US20060160995A1 (en) | 2006-07-20 |
| ES2289528T3 (es) | 2008-02-01 |
| WO2005000891A2 (en) | 2005-01-06 |
| EP1636261B1 (en) | 2007-08-01 |
| ATE368687T1 (de) | 2007-08-15 |
| DE602004007924D1 (de) | 2007-09-13 |
| US7541439B2 (en) | 2009-06-02 |
| DE602004007924T2 (de) | 2008-04-10 |
| EP1636261A2 (en) | 2006-03-22 |
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